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Zu "K13304" wurden 25 Artikel gefunden!
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Artikelnummer: Cay41170-1
SGK3-PROTAC1 is a proteolysis-targeting chimera (PROTAC) containing the serum/glucocorticoid-regulated kinase 3 (SGK3) inhibitor 308-R conjugated to VHL ligand 1 (Cay-21591) via an alkyl linker with two PEG units. It inhibits SGK3, SGK1, and p70 ribosomal S6 kinase 1 (S6K1, IC50s = 0. 0. and 1. µM, respectively) but...
| Schlagworte: | Serum/Glucocorticoid-regulated Kinase 3-PROTAC1, Serum/Glucocorticoid-regulated Kinase 3-Proteolysis-targeting Chimera 1,... |
| Anwendung: | SGK3 degradation driving PROTAC |
| CAS | 2381320-35-8 |
| MW: | 1157.38 D |
ab 340,00 €
Artikelnummer: ARG55791.100
Protein function: Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, proliferation, survival and migration. Up-regulates Na(+) channels: SCNN1A/ENAC and SCN5A, K(+) channels: KCNA3/KV1.3, KCNE1, KCNQ1 and KCNH2/HERG, epithelial...
| Schlagworte: | Anti-CISK, Anti-SGK3, EC=2.7.11.1, Anti-Cytokine-independent survival kinase, Anti-Serine/threonine-protein kinase Sgk3,... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
616,00 €
Artikelnummer: BPS-40273
Recombinant full-length human SGK3, also known as CISK and SGKL, (Genbank Accession No. NM_013257) with an N-terminal GST-tag, expressed in Sf9 insect cells using a baculovirus expression system.
| Schlagworte: | SGK3, CISK, EC=2.7.11.1, Serine/threonine-protein kinase Sgk3, Cytokine-independent survival kinase,... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 82 kD |
901,00 €
Artikelnummer: ATA-HPA027146.100
Protein function: Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, proliferation, survival and migration. Up-regulates Na(+) channels: SCNN1A/ENAC and SCN5A, K(+) channels: KCNA3/KV1.3, KCNE1, KCNQ1 and KCNH2/HERG, epithelial...
| Schlagworte: | Anti-SGK3, Anti-CISK, EC=2.7.11.1, Anti-Serine/threonine-protein kinase Sgk3, Anti-Cytokine-independent survival kinase,... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 246,00 €
Artikelnummer: NSJ-F54957-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. SGK3, a Ser/Thr protein kinase, is similar to serum- and glucocorticoid-induced protein kinase (SGK), but this gene product is not induced by serum or glucocorticoids. Expression is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also...
| Schlagworte: | Anti-CISK, Anti-SGK3, EC=2.7.11.1, Anti-Cytokine-independent survival kinase, Anti-Serine/threonine-protein kinase Sgk3,... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Artikelnummer: TGM-TMPY-04561-50ug
Description: Serine / threonine-protein kinase Sgk3, also known as Serum / glucocorticoid-regulated kinase 3, Serum / glucocorticoid-regulated kinase-like and SGK3, is a cytoplasmic vesicle protein that belongs to the protein kinase superfamily and AGC Ser/Thr protein kinase family. SGK3 contains one AGC-kinase...
| Schlagworte: | SGKL, SGK2, CISK, serum/glucocorticoid regulated kinase family, member 3 |
| MW: | 85 kD |
433,00 €
Artikelnummer: TGM-TMPY-04561-10ug
Description: Serine / threonine-protein kinase Sgk3, also known as Serum / glucocorticoid-regulated kinase 3, Serum / glucocorticoid-regulated kinase-like and SGK3, is a cytoplasmic vesicle protein that belongs to the protein kinase superfamily and AGC Ser/Thr protein kinase family. SGK3 contains one AGC-kinase...
| Schlagworte: | SGKL , serum/glucocorticoid regulated kinase family, member 3 , SGK2 , CISK |
| MW: | 85 kD |
ab 72,00 €
Artikelnummer: ABS-PP-9282-L.100
Protein function: Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, proliferation, survival and migration. Up-regulates Na(+) channels: SCNN1A/ENAC and SCN5A, K(+) channels: KCNA3/KV1.3, KCNE1, KCNQ1 and KCNH2/HERG, epithelial...
| Schlagworte: | Serine/threonine-protein kinase Sgk3, Cytokine-independent survival kinase, Serum/glucocorticoid-regulated kinase 3,... |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 19.5 kD |
ab 115,00 €
Artikelnummer: S1010-85W.50
SGKL/SGK3, also known as CISK for cytokine-independent survival kinase, is a SGK type protein kinase. The protein contains a lipid-binding phox homology (PX) domain, which is required for targeting SGKL/SGK3 protein to the endosomal compartment. SGKL/SGK3 functions downstream of the phosphoinositide 3-kinase (PI3K)...
| Schlagworte: | Anti-CISK, EC=2.7.11.1, Anti-Serine/threonine-protein kinase Sgk3, Anti-Cytokine-independent survival kinase,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
802,00 €
Artikelnummer: VHPS-8330
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | DKFZp781N0293, Putative uncharacterized protein DKFZp781N0293 |
| Anwendung: | RNA quantification |
45,00 €
Artikelnummer: 041663.200
Sgk3 is involved in the activation of potassium channels (By similarity). Mediates cell IL-3-dependent survival signals. Can inhibit pro-apoptotic FOXO3A in vitro. Applications: Suitable for use in Western Blot and ELISA. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000, Optimal dilutions...
| Schlagworte: | Anti-Sgk3, Anti-Cisk, EC=2.7.11.1, Anti-Serine/threonine-protein kinase Sgk3, Anti-Cytokine-independent survival kinase,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
865,00 €
Artikelnummer: 041665.200
SGK3, a Ser/Thr protein kinase, is similar to serum- and glucocorticoid-induced protein kinase (SGK), but this gene product is not induced by serum or glucocorticoids. Expression is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK. Applications: Suitable for use...
| Schlagworte: | Anti-SGK3, Anti-CISK, EC=2.7.11.1, Anti-Serine/threonine-protein kinase Sgk3, Anti-Cytokine-independent survival kinase,... |
| Anwendung: | ELISA, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
865,00 €