Zu "K13294" wurden 3 Artikel gefunden!
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BAY 60-7550
Artikelnummer: Cay10011135-1
The second messengers cAMP and cGMP are important mediators of signal transduction and hence a wide range of cellular processes including vasodilation and synaptic plasticity. Type 2 cyclic nucleotide phosphodiesterases (PDE2) isoforms inactivate cAMP and cGMP by hydrolyzing the phosphodiester bond. BAY 60-7550 is a...
| Schlagworte: | 2-[(3,4-dimethoxyphenyl)methyl]-7-[(1R)-1-hydroxyethyl]-4-phenylbutyl]-5-methyl-imidazo[5,1-f][1,2,4]triazin-4(1H)-one |
| Anwendung: | PDE2 inhibitor |
| CAS | 439083-90-6 |
| MW: | 476.6 D |
ab 128,00 €
Bucladesine (sodium salt)
Artikelnummer: Cay14408-50
Bucladesine is a cell-permeable, cyclic nucleotide derivative that mimics the action of endogenous cyclic adenosine monophosphate (cAMP) and is a phosphodiesterase inhibitor. Because it mimics cAMP and can induce normal physiological responses when added to cells in experimental conditions, bucladesine is widely...
| Schlagworte: | DC 2797, N-(1-oxobutyl)-cyclic 3',5'-(hydrogen phosphate) 2'-butanoate-adenosine, monosodium salt |
| Anwendung: | Cell-permeable cAMP mimic |
| CAS | 16980-89-5 |
| MW: | 491.4 D |
ab 49,00 €
BAY-60-7550
Artikelnummer: BPS-27215
BAY-60-7550 is a potent inhibitor of PDE2. It is more selective for PDE2 than PDE1 by 50-fold. Similarly, it is 100-fold more selective for PDE4B, PDE5B, PDE7B, PDE8A, PDE9A, PDE10A, and PDE11A.
| Anwendung: | PDE2 inhibitor |
| MW: | 476.6 D |
827,00 €
