Zu "K13129" wurden 75 Artikel gefunden!
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NEU
Anti-Recombinant Gemin 1, clone C122811
Artikelnummer: E-AN303191L.100
Protein function: The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs (PubMed:18984161, PubMed:9845364). Most spliceosomal snRNPs contain a common set of Sm proteins...
| Schlagworte: | Anti-SMN2, Anti-SMN1, Anti-Gemin-1, Anti-Component of gems 1, Anti-Survival motor neuron protein, Recombinant Gemin 1... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human,mouse,rat |
ab 171,00 €
NEU
Anti-Recombinant Gemin 1, clone C112113
Artikelnummer: E-AN302493L.100
Protein function: The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs (PubMed:18984161, PubMed:9845364). Most spliceosomal snRNPs contain a common set of Sm proteins...
| Schlagworte: | Anti-SMN2, Anti-SMN1, Anti-Gemin-1, Anti-Component of gems 1, Anti-Survival motor neuron protein, Recombinant Gemin 1... |
| Anwendung: | WB, IHC, IF, IP, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human,mouse,rat |
ab 171,00 €
Human SMN1 (Survival Of Motor Neuron 1, Centromeric)...
Artikelnummer: ELK-ELK0922MS.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human SMN1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human SMN1. Next,...
| Schlagworte: | SMN1, SMN2, Gemin-1, Component of gems 1, Survival motor neuron protein |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 374,00 €
Human SMN2 (Survival Of Motor Neuron 2, Centromeric)...
Artikelnummer: ELK-ELK3655MS.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human SMN2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human SMN2. Next,...
| Schlagworte: | SMN1, SMN2, Gemin-1, Component of gems 1, Survival motor neuron protein |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 374,00 €
SMN1 Protein, Mouse, Recombinant (His & Myc)
Artikelnummer: TGM-TMPH-02920-10ug
Description: SMN1 Protein, Mouse, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 35.3 kDa and the accession number is P97801.
| Schlagworte: | Smn1 , Survival motor neuron protein , Smn |
| MW: | 35.3 kD |
ab 157,00 €
Risdiplam
Artikelnummer: Cay29028-5
Risdiplam is a survival of motor neuron-2 (SMN2) splicing modifier. It enhances SMN2 splicing (EC1.5x = 40 nM) and increases SMN protein levels (EC1.5x = 163 nM) in cellular assays. Risdiplam (3 mg/kg) increases brain and quadricep muscle SMN protein levels in the adult C/C-allele mouse model of mild spinal muscular...
| Schlagworte: | RG-7916, RO7034067,... |
| Anwendung: | SMN2 splicing modifier |
| CAS | 1825352-65-5 |
| MW: | 401.5 D |
ab 58,00 €
Anti-SMN1
Artikelnummer: A301-863A
Protein function: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2,...
| Schlagworte: | Anti-SMN, Anti-SMN1, Anti-SMN2, Anti-SMNC, Anti-Gemin-1, Anti-Component of gems 1, Anti-Survival motor neuron protein |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
LMI070
Artikelnummer: Cay26757-1
LMI070 is an SMN2 splice modulator. It selectively enhances SMN2 splicing by stabilizing the complex formed by the U1 small nuclear ribonucleic protein (snRNP) and SMN2 pre-mRNA. LMI070 (3-30 mg/kg) increases the expression of the full-length SMN2 trancript and, at doses ranging from 0.3 to 30 mg/kg, increases SMN...
| Schlagworte: | Branaplam, NVS-SM1, 5-(1H-pyrazol-4-yl)-2-[6-[(2,2,6,6-tetramethyl-4-piperidinyl)oxy]-3-pyridazinyl]-phenol |
| Anwendung: | SMN2 splice modulator |
| CAS | 1562338-42-4 |
| MW: | 393.5 D |
ab 69,00 €
Branaplam
Artikelnummer: TGM-T4641-2mg
Description: Branaplam (LMI 070) is a highly potent, selective and orally active small molecule SMN2 splicing modulator. Target: Potassium Channel, Others, DNA/RNA Synthesis. Smiles: CC1(C)CC(CC(C)(C)N1)Oc1ccc(nn1)-c1ccc(cc1O)-c1cn[nH]c1. References: Palacino J, et al. SMN2 splice modulators enhance U1-pre-mRNA...
| Schlagworte: | LMI 070, NVS-SM1 |
| Anwendung: | Targets survival motor neuron protein (SMN) |
| CAS | 1562338-42-4 |
| MW: | 393.48 D |
ab 40,00 €
Anti-Survival Motor Neuron Protein (human), clone 7B10
Artikelnummer: AG-20T-0003-C200
Monoclonal Antibody. Recognizes a sequence of up to 9 amino acids in the N-terminal domain of human SMN. Isotype: Mouse IgG1. Clone: 7B10. Applications: IP, WB. Liquid. In PBS. The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the...
| Schlagworte: | Anti-SMN, Anti-SMN1, Anti-SMNC, Anti-SMN2, Anti-Gemin-1, Anti-Component of gems 1, Anti-Survival motor neuron protein |
| Anwendung: | IP, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
385,00 €
Anti-SMN1 / SMN2, Internal
Artikelnummer: ARG64148.100
Protein function: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2,...
| Schlagworte: | Anti-SMN, Anti-SMN2, Anti-SMNC, Anti-SMN1, Anti-Gemin-1, Anti-Component of gems 1, Anti-Survival motor neuron protein |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Anti-SMN1
Artikelnummer: A301-862A
Protein function: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2,...
| Schlagworte: | Anti-SMN, Anti-SMN1, Anti-SMN2, Anti-SMNC, Anti-Gemin-1, Anti-Component of gems 1, Anti-Survival motor neuron protein |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €