Zu "K13129" wurden 50 Artikel gefunden!

1 von 5 Seiten
Für die Filterung wurden keine Ergebnisse gefunden!
-10 %
Rabattaktion
Human SMN1 (Survival Of Motor Neuron 1, Centromeric) ELISA Kit
Human SMN1 (Survival Of Motor Neuron 1, Centromeric)...

Artikelnummer: ELK-ELK0922.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human SMN1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human SMN1. Next,...
Schlagworte: SMN, SMN1, SMNC, SMN2, Gemin-1, Component of gems 1, Survival motor neuron protein
Anwendung: ELISA
Spezies-Reaktivität: human
365,00 € ab 328,50 €
Bewerten
Risdiplam
Risdiplam

Artikelnummer: Cay29028-5

Risdiplam is a survival of motor neuron-2 (SMN2) splicing modifier. It enhances SMN2 splicing (EC1.5x = 40 nM) and increases SMN protein levels (EC1.5x = 163 nM) in cellular assays. Risdiplam (3 mg/kg) increases brain and quadricep muscle SMN protein levels in the adult C/C-allele mouse model of mild spinal muscular...
Schlagworte: RG-7916, RO7034067,...
Anwendung: SMN2 splicing modifier
CAS 1825352-65-5
MW: 401.5 D
ab 50,00 €
Bewerten
Anti-SMN1
Anti-SMN1

Artikelnummer: A301-863A

Protein function: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2,...
Schlagworte: Anti-SMN, Anti-SMN1, Anti-SMN2, Anti-SMNC, Anti-Gemin-1, Anti-Component of gems 1, Anti-Survival motor neuron protein
Anwendung: WB, IP
Wirt: Rabbit
Spezies-Reaktivität: human
ab 164,00 €
Bewerten
LMI070
LMI070

Artikelnummer: Cay26757-1

LMI070 is an SMN2 splice modulator. It selectively enhances SMN2 splicing by stabilizing the complex formed by the U1 small nuclear ribonucleic protein (snRNP) and SMN2 pre-mRNA. LMI070 (3-30 mg/kg) increases the expression of the full-length SMN2 trancript and, at doses ranging from 0.3 to 30 mg/kg, increases SMN...
Schlagworte: Branaplam, NVS-SM1, 5-(1H-pyrazol-4-yl)-2-[6-[(2,2,6,6-tetramethyl-4-piperidinyl)oxy]-3-pyridazinyl]-phenol
Anwendung: SMN2 splice modulator
CAS 1562338-42-4
MW: 393.5 D
ab 60,00 €
Bewerten
-10 %
Anti-Survival Motor Neuron Protein (human), clone 7B10
Anti-Survival Motor Neuron Protein (human), clone 7B10

Artikelnummer: AG-20T-0003-C200

Monoclonal Antibody. Recognizes a sequence of up to 9 amino acids in the N-terminal domain of human SMN. Isotype: Mouse IgG1. Clone: 7B10. Applications: IP, WB. Liquid. In PBS. The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the...
Schlagworte: Anti-SMN, Anti-SMN1, Anti-SMNC, Anti-SMN2, Anti-Gemin-1, Anti-Component of gems 1, Anti-Survival motor neuron protein
Anwendung: IP, WB
Wirt: Mouse
Spezies-Reaktivität: human
330,00 € 297,00 €
Bewerten
Anti-SMN1 / SMN2, Internal
Anti-SMN1 / SMN2, Internal

Artikelnummer: ARG64148.100

Protein function: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2,...
Schlagworte: Anti-SMN, Anti-SMN2, Anti-SMNC, Anti-SMN1, Anti-Gemin-1, Anti-Component of gems 1, Anti-Survival motor neuron protein
Anwendung: ELISA, WB
Wirt: Goat
Spezies-Reaktivität: human
784,00 €
Bewerten
Anti-SMN1
Anti-SMN1

Artikelnummer: A301-862A

Protein function: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2,...
Schlagworte: Anti-SMN, Anti-SMN1, Anti-SMN2, Anti-SMNC, Anti-Gemin-1, Anti-Component of gems 1, Anti-Survival motor neuron protein
Anwendung: WB, IP
Wirt: Rabbit
Spezies-Reaktivität: human
ab 164,00 €
Bewerten
SMN tudor domain (human recombinant)
SMN tudor domain (human recombinant)

Artikelnummer: Cay14136-100

Tudor domains are small protein structural motifs of ~50 amino acids related to the "Royal family" of methyl readers, which also includes chromo, MBT, PWWP, and Agenet-like domains. Tudor domains occur either alone, in tandem, or with other domains and are found in many proteins that are involved in RNA metabolism,...
Schlagworte: SMN, SMN1, SMN2, SMNC, Gemin-1, Gemin-1, Component of gems 1, Component of gems 1, Survival motor neuron protein, Survival...
Anwendung: Binding assays
Exprimiert in: E.coli
Ursprungsart: human
MW: 42,6 kD
465,00 €
Bewerten
Mouse SMN1 / Survival of Motor Neuron 1, Telomeric ELISA Kit
Mouse SMN1 / Survival of Motor Neuron 1, Telomeric ELISA Kit

Artikelnummer: G-MOFI01117.96

Anwendung: ELISA
Spezies-Reaktivität: mouse
694,00 €
Bewerten
Anti-SMN1/2 / Survival of Motor Neuron 1/2
Anti-SMN1/2 / Survival of Motor Neuron 1/2

Artikelnummer: NSJ-R32249

0.5mg/ml if reconstituted with 0.2ml sterile DI water. The Survival of Motor Neuron gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of...
Schlagworte: Anti-SMN, Anti-SMNC, Anti-SMN1, Anti-SMN2, Anti-Gemin-1, Anti-Component of gems 1, Anti-Survival motor neuron protein,...
Anwendung: WB, IHC (paraffin)
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
755,00 €
Bewerten
Anti-SMN
Anti-SMN

Artikelnummer: NSJ-R33427-100UG

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Survival of motor neuron, SMN1, SMN2 Protein function: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome....
Schlagworte: Anti-SMN, Anti-SMN1, Anti-SMNC, Anti-SMN2, Anti-Gemin-1, Anti-Component of gems 1, Anti-Survival motor neuron protein, SMN...
Anwendung: WB, ELISA (peptide)
Wirt: Goat
Spezies-Reaktivität: human
755,00 €
Bewerten
Cuspin-1
Cuspin-1

Artikelnummer: Cay18526-10

The Survival of Motor Neurons (SMN) protein participates in RNA splicing. Decreases in SMN, typically a consequence of defects in the smn1 gene, result in the death of motor neurons and lead to the neurodegenerative disease, spinal muscular atrophy (SMA). Cuspin-1 is a small molecule upregulator of SMN that has been...
Schlagworte: Chemical Upregulator of SMN Protein-1, (5-bromo-3-pyridinyl)(4-methylphenyl)-methanone
Anwendung: SMN upregulator
CAS 337932-29-3
MW: 276.1 D
ab 77,00 €
Bewerten
1 von 5 Seiten