Zu "K12828" wurden 28 Artikel gefunden!
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Pladienolide B
Artikelnummer: Cay16538-100
Spliceosomes mediate the processing of pre-mRNA into mature mRNA. Each spliceosome is a multiunit complex containing several proteins and RNA molecules that work in unison to repeatedly cleave and rejoin segments of mRNA.{27002, 27000} Pladienolide B is a macrocyclic lactone that selectively binds splicing factor 3b...
| Schlagworte: | (4R,7R,8S,9E,11S,12S)-8-(acetyloxy)-4,7-dihydroxy-12-[(1E,3E,5S)-6-[(2R,3R)-3-[(1R,2S)-2-hydroxy-1-methylbutyl]-2-oxiranyl... |
| Anwendung: | mRNA splicing inhibitor, splicing factor 3B inhibitor |
| CAS | 445493-23-2 |
| MW: | 536.7 D |
ab 177,00 €
Anti-SF3b155/SAP155
Artikelnummer: A300-996A
Protein function: Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also...
| Schlagworte: | Anti-SF3B1, Anti-SAP155, Anti-SAP 155, Anti-SF3b155, Anti-Splicing factor 3B subunit 1, Anti-Spliceosome-associated... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-SF3b155/SAP155
Artikelnummer: A300-997A
Protein function: Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also...
| Schlagworte: | Anti-SF3B1, Anti-SAP155, Anti-SAP 155, Anti-SF3b155, Anti-Splicing factor 3B subunit 1, Anti-Spliceosome-associated... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-SF3b155/SAP155 (IHC)
Artikelnummer: IHC-00214
Protein function: Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also...
| Schlagworte: | Anti-SF3B1, Anti-SAP155, Anti-SAP 155, Anti-SF3b155, Anti-Splicing factor 3B subunit 1, Anti-Spliceosome-associated... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-SF3B1
Artikelnummer: ATA-HPA050275.100
Protein function: Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex (PubMed:27720643). SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of...
| Schlagworte: | Anti-SF3B1, Anti-SAP155, Anti-SF3b155, Anti-SAP 155, Anti-Splicing factor 3B subunit 1, Anti-Spliceosome-associated... |
| Anwendung: | WB, IHC, ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
Anti-SF3B1
Artikelnummer: CSB-PA004648.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-SF3B1, Anti-SAP155, Anti-SAP 155, Anti-SF3b155, Anti-Splicing factor 3B subunit 1, Anti-Spliceosome-associated... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 126,00 €
Anti-SF3B1 Recombinant Monoclonal, clone 6C7
Artikelnummer: CSB-RA102629A0HU.100
Isotype: Rabbit IgG. Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Affinity-chromatography. Target Name: SF3B1. Antigen Species: Human
| Schlagworte: | Anti-SF3B1, Anti-SAP155, Anti-SAP 155, Anti-SF3b155, Anti-Splicing factor 3B subunit 1, Anti-Spliceosome-associated... |
| Anwendung: | ELISA, WB, IHC, IF, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 201,00 €
![Anti-SF3B1 [R01-8T1] Monoclonal Antibody](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg "Anti-SF3B1 [R01-8T1] Monoclonal Antibody")
Anti-SF3B1 [R01-8T1] Monoclonal Antibody
Artikelnummer: G-AGMB02672.100
SF3B1 Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: Component of the 17S U2 SnRNP complex of the spliceosome, a large ribonucleoprotein complex that removes introns from transcribed pre-mRNAs (PubMed:12234937, PubMed:27720643, PubMed:32494006,...
| Schlagworte: | Anti-SF3B1, Anti-Splicing factor 3B subunit 1, Anti-Spliceosome-associated protein 155, Anti-Pre-mRNA-splicing factor SF3b... |
| Anwendung: | WB, IHC-P, ICC/IF, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 134,00 €
Anti-SF3B1 [R08-6I2] Monoclonal Antibody
Artikelnummer: G-AGMB02549.100
SF3B1 Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: Component of the 17S U2 SnRNP complex of the spliceosome, a large ribonucleoprotein complex that removes introns from transcribed pre-mRNAs (PubMed:12234937, PubMed:27720643, PubMed:32494006,...
| Schlagworte: | Anti-SF3B1, Anti-Splicing factor 3B subunit 1, Anti-Spliceosome-associated protein 155, Anti-Pre-mRNA-splicing factor SF3b... |
| Anwendung: | WB, IHC-P, ICC/IF, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 134,00 €
Anti-Recombinant SF3B1, clone R08-6I2
Artikelnummer: E-AB-81510.100
This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence...
| Schlagworte: | Anti-SF3B1, Anti-SAP155, Anti-SAP 155, Anti-SF3b155, Anti-Splicing factor 3B subunit 1, Anti-Spliceosome-associated... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, hamster |
ab 195,00 €
SF3B1 (human), recombinant protein
Artikelnummer: ABS-PP-5960-L.100
Protein function: Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex (PubMed:27720643). SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of...
| Schlagworte: | Splicing factor 3B subunit 1, Pre-mRNA-splicing factor SF3b 155 kDa subunit, SF3b155, Spliceosome-associated protein 155,... |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 34 kD |
ab 115,00 €
H3B-8800
Artikelnummer: Cay42106-1
An inhibitor of the SF3B complex, binds to SF3B complexes containing wild-type SF3B (IC50 = 1.4 nM) or various SF3B mutations (IC50s = 0.3-1.8 nM), inhibits SF3B1-induced splicing of canonical and aberrant pre-mRNA junctions in HEK293T nuclear extracts overexpressing SF3B1K700E, selectively inhibits the growth of,...
| Schlagworte: | 4-methyl-1-piperazinecarboxylic acid,... |
| Anwendung: | SF3B complex inhibitor |
| CAS | 1825302-42-8 |
| MW: | 555.71 D |
ab 177,00 €