Zu "K12800" wurden 80 Artikel gefunden!
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Anti-NLRP3/NALP3, clone Cryo-2
Artikelnummer: AG-20B-0014-C100
Recognizes mouse and human NLRP3/NALP3. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the...
| Schlagworte: | NACHT-, LRR- and PYD-containing Protein 3, NLRP3, Cryopyrin, Cold Autoinflammatory Syndrome 1 Protein |
| Anwendung: | IHC, IP, WB, ICC, ChIP |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human , mouse |
374,00 €
Human NLRP3 (NLR Family, Pyrin Domain Containing Protein...
Artikelnummer: ELK-ELK5399.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human NLRP3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human NLRP3. Next,...
| Schlagworte: | CLR1.1, Cryopyrin, Caterpiller protein 1.1, PYRIN-containing APAF1-like protein 1, Angiotensin/vasopressin receptor... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Rat NLRP3 (NLR Family, Pyrin Domain Containing Protein 3)...
Artikelnummer: ELK-ELK7621.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat NLRP3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat NLRP3. Next,...
| Schlagworte: | NACHT, LRR and PYD domains-containing protein 3 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 365,00 €
Mouse NLRP3 (NLR Family, Pyrin Domain Containing Protein...
Artikelnummer: ELK-ELK8421.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse NLRP3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse NLRP3. Next,...
| Schlagworte: | Cryopyrin, PYRIN-containing APAF1-like protein 1, NACHT, LRR and PYD domains-containing protein 3, Cold autoinflammatory... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
NLRP3 Knockdown THP-1 Cell Pool
Artikelnummer: BPS-82121
NLRP3 Knockdown THP-1 Cell Pool is a cell pool of THP-1 human monocytic cells. This cell pool was generated by using NLRP3 Human shRNA Lentivirus (BPS Bioscience #82122) to create a THP-1 cell pool with stable knockdown of NLRP3 (NLR family pyrin domain containing 3). THP-1 cells are the most commonly used model...
| Schlagworte: | CLR1.1, Cryopyrin, Caterpiller protein 1.1, PYRIN-containing APAF1-like protein 1, Angiotensin/vasopressin receptor... |
| Anwendung: | NLRP3 knockdown effect on cellular function studies |
| Spezies-Reaktivität: | human |
1.817,00 €
NLRP3 Human shRNA Lentivirus
Artikelnummer: BPS-82122
The NLRP3 shRNA Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce nearly all types of mammalian cells, including primary and non-dividing cells. These particles contain 3 shRNAs (Short hairpin RNA) targeting human NLRP3 driven by a U6 promoter,...
| Schlagworte: | CLR1.1, Cryopyrin, Caterpiller protein 1.1, PYRIN-containing APAF1-like protein 1, Angiotensin/vasopressin receptor... |
| Anwendung: | NLRP3 knockdown cell pool / cell line generation (puromycin selection/limiting dilution) |
| Spezies-Reaktivität: | human |
1.389,00 €
MCC950 . Na
Artikelnummer: AG-CR1-3615-M001
Crystalline solid. Soluble in water (10mg/ml), DMSO (10mg/ml), dimethyl formamide or ethanol (1mg/ml). Chemical. CAS: 256373-96-3. Formula: C20H23N2NaO5S. MW: 426.5. Synthetic. Potent, selective and orally available NLRP3 inflammasome inhibitor. Blocks the release of IL-1beta in macrophages primed with LPS and...
| Schlagworte: | MCC950, CP-456,773, CRID3, 1-(1,2,3,5,6,7-Hexahydro- s-indacen-4-yl)-3-[4-(1-hydroxy-1-methyl-ethyl)-furan-2-sulfonyl]urea |
| Anwendung: | NLRP3 inflammasome inhibitor |
| CAS | 256373-96-3 |
| MW: | 426,5 D |
ab 39,00 €
MCC950
Artikelnummer: Cay17510-1
MCC950 is an inhibitor of NOD-like receptor protein 3 (NLRP3) inflammasome activation. It inhibits ATP-induced IL-1beta release in LPS-primed mouse bone marrow-derived macrophages (BMDMs, IC50 = 7.5 nM), as well as cytosolic LPS-induced IL-1beta release in Pam3CSK4-primed mouse BMDMs at 0.1 and 1 µM, indicating...
| Schlagworte: | CP 456,773, N-[[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-2-furansulfonamide |
| Anwendung: | NLRP3 inhibitor |
| CAS | 210826-40-7 |
| MW: | 404.5 D |
ab 109,00 €
NALP3 (delPYD), FLAG-Tag
Artikelnummer: BPS-100454
Human NLR Family Pyrin Domain Containing 3 (NLRP3), also known as NALP3, Cold Autoinflammatory Syndrome 1 Protein (CIAS1), cryopyrin and PYPAF1, Genbank Accession No. NM_004895, a.a. 134-1036(end) with N-terminal FLAG-tag, expressed in a HEK293 expression system. MW = 105 kDa.
| Schlagworte: | CLR1.1, Cryopyrin, Caterpiller protein 1.1, PYRIN-containing APAF1-like protein 1, Angiotensin/vasopressin receptor... |
| Anwendung: | Immunotherapy studies |
| Exprimiert in: | human cells |
| Ursprungsart: | human |
| MW: | 120 kD |
745,00 €
Anti-NLRP3/NALP3 (mouse), clone Cryo-1
Artikelnummer: AG-20B-0006-C100
Recognizes mouse NLRP3/NALP3. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like...
| Schlagworte: | NACHT-, LRR- and PYD-containing Protein 3, NLRP3, Cryopyrin, Cold Autoinflammatory Syndrome 1 Protein |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | mouse |
462,00 €
Monosodium urate (crystals)
Artikelnummer: AG-CR1-3950-2002
NLRP3/NALP3 inflammasome activator. Specially crystallized and tested for biological activity. Stimulates the caspase-1 activating NLRP3/NALP3 inflammasome, resulting in the production of active IL-1beta and IL-18.
| Schlagworte: | MSU (crystals), Uric acid (crystals) |
| Anwendung: | NLRP3/NALP3 inflammasome activator |
| Wirt: | Synthetic |
| CAS | 1198-77-2 |
| MW: | 167,1 D |
ab 92,00 €
NALP3 (CIAS1) Human Recombinant Protein
Artikelnummer: BPS-80117
Human NLR Family Pyrin Domain Containing 3 (NLRP3), also known as NALP3, Cold Autoinflammatory Syndrome 1 Protein (CIAS1), cryopyrin and PYPAF1 (Genbank Accession No. NM_004895), a.a. 2-1036(end) with N-terminal His-FLAG-tag, expressed in a baculovirus infected Sf9 cell expression system. MW = 120 kDa (calculated)....
| Schlagworte: | CLR1.1, Cryopyrin, Caterpiller protein 1.1, PYRIN-containing APAF1-like protein 1, Angiotensin/vasopressin receptor... |
| Anwendung: | Protein function studies, inhibitor screening |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 120 kD |
818,00 €