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Zu "K12584" wurden 17 Artikel gefunden!
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Artikelnummer: A305-426A
Protein function: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) with up to 10 nucleotide substrates...
| Schlagworte: | Anti-DCS1, Anti-DCPS, Anti-DCS-1, Anti-HINT-5, Anti-HSPC015, EC=3.6.1.59, Anti-m7GpppX diphosphatase, Anti-Decapping... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Artikelnummer: A305-444A
Protein function: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) with up to 10 nucleotide substrates...
| Schlagworte: | Anti-DCS1, Anti-DCPS, Anti-DCS-1, Anti-HINT-5, Anti-HSPC015, EC=3.6.1.59, Anti-m7GpppX diphosphatase, Anti-Decapping... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Artikelnummer: ATA-HPA039632.100
Protein function: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) with up to 10 nucleotide substrates...
| Schlagworte: | Anti-DCS1, Anti-DCPS, Anti-DCS-1, Anti-HINT-5, Anti-HSPC015, EC=3.6.1.59, Anti-m7GpppX diphosphatase, Anti-Decapping... |
| Anwendung: | WB, IHC, ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 369,00 €
Artikelnummer: ATA-HPA058597.100
Protein function: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) with up to 10 nucleotide substrates...
| Schlagworte: | Anti-DCS1, Anti-DCPS, Anti-DCS-1, Anti-HINT-5, Anti-HSPC015, EC=3.6.1.59, Anti-m7GpppX diphosphatase, Anti-Decapping... |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 369,00 €
Artikelnummer: Cay36589-1
RG3039 is an inhibitor of mRNA decapping scavenger enzyme (DcpS, IC50 = 0.069 nM). It prevents denervation of the neuromuscular junction (NMJ) and decreases in NMJ synaptic transmission and myofiber size of the longissimus muscle in a mouse model of spinal muscular atrophy (SMA) induced by knockout of the gene...
| Schlagworte: | 5-[[1-[(2,6-dichlorophenyl)methyl]-4-piperidinyl]methoxy]-2,4-quinazolinediamine |
| Anwendung: | DcpS (m7GpppX diphosphatase) inhibitor |
| CAS | 1005504-62-0 |
| MW: | 432.4 D |
ab 53,00 €
Artikelnummer: TGM-T3336-100mg
Description: Rg3039 (PF-06687859) is a potent DcpS inhibitor. DcpS is a therapeutic target for spinal muscular atrophy. Spinal muscular atrophy (SMA) is caused by deletion or mutation of both copies of the SMN1 gene which produces an essential protein known as SMN. RG3039 improves motor function in SMA mice. RG3039...
| Schlagworte: | PF-06687859 |
| Anwendung: | DcpS (m7GpppX diphosphatase) inhibitor |
| CAS | 1005504-62-0 |
| MW: | 432.35 D |
ab 31,00 €
Artikelnummer: 351180.50
Recombinant protein corresponding to aa1-337 from human DCPS, fused to His-tag at N-terminal expressed in E. coli. Protein function: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. Hydrolyzes cap...
| Schlagworte: | DCS1, DCPS, DCS-1, HINT-5, HSPC015, EC=3.6.1.59, m7GpppX diphosphatase, Decapping scavenger enzyme, Histidine triad... |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 40.8 kD |
ab 606,00 €
Artikelnummer: ABS-PP-3854-L.100
Protein function: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) with up to 10 nucleotide substrates...
| Schlagworte: | m7GpppX diphosphatase, DCS-1, Decapping scavenger enzyme, Hint-related 7meGMP-directed hydrolase, Histidine triad... |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 39.5 kD |
ab 115,00 €
Artikelnummer: 034515.200
Necessary for the complete degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA fragments shorter than 10 nucleotides that are produced by 3'->5' exosome-mediated mRNA decay. Releases m7GMP. Can also degrade m7GDP to m7GMP. Has...
| Schlagworte: | Anti-DCPS, Anti-DCS1, Anti-DCS-1, Anti-HINT-5, Anti-HSPC015, EC=3.6.1.59, Anti-m7GpppX diphosphatase, Anti-Decapping... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
865,00 €
Artikelnummer: ATA-APrEST80526.100
Protein function: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) with up to 10 nucleotide substrates...
| Schlagworte: | DCS1, DCPS, DCS-1, HINT-5, HSPC015, EC=3.6.1.59, m7GpppX diphosphatase, Decapping scavenger enzyme, Histidine triad... |
| Anwendung: | Control antigen |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
264,00 €
Artikelnummer: ATA-APrEST91931.100
Protein function: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) with up to 10 nucleotide substrates...
| Schlagworte: | DCS1, DCPS, DCS-1, HINT-5, HSPC015, EC=3.6.1.59, m7GpppX diphosphatase, Decapping scavenger enzyme, Histidine triad... |
| Anwendung: | Control antigen |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
264,00 €
Artikelnummer: G-CAB10299.20
Protein function: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) with up to 10 nucleotide substrates...
| Schlagworte: | Anti-DCS1, Anti-DCPS, Anti-DCS-1, Anti-HINT-5, Anti-HSPC015, EC=3.6.1.59, Anti-m7GpppX diphosphatase, Anti-Decapping... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
103,00 €