- Suchergebnis für K12367
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Zu "K12367" wurden 21 Artikel gefunden!
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Artikelnummer: G-CAB3595.100
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
398,00 €
Artikelnummer: A305-399A
Protein function: Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation...
| Schlagworte: | Anti-DOCK2, Anti-KIAA0209, Anti-Dedicator of cytokinesis protein 2 |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Artikelnummer: A305-400A
Protein function: Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation...
| Schlagworte: | Anti-DOCK2, Anti-KIAA0209, Anti-Dedicator of cytokinesis protein 2 |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Artikelnummer: Cay17386-10
CPYPP is an inhibitor of the Rac activators dedicator of cytokinesis 2 (DOCK2, IC50 = 22.8 µM for DOCK2 guanine nucleotide exchange factor (GEF) activity), DOCK5, and DOCK180. It is selective for these DOCK-A subfamily proteins over the DOCK-D subfamily member DOCK9. CPYPP (100 µM) prevents chemokine-induced Rac...
| Schlagworte: | 4-[3-(2-chlorophenyl)-2-propen-1-ylidene]-1-phenyl-3,5-pyrazolidinedione |
| Anwendung: | DOCK2 / DOCK5 / DOCK180 inhibitor |
| CAS | 310460-39-0 |
| MW: | 324.8 D |
ab 105,00 €
Artikelnummer: ATA-HPA036469.100
Protein function: Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation...
| Schlagworte: | Anti-DOCK2, Anti-KIAA0209, Anti-Dedicator of cytokinesis protein 2 |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
491,00 €
Artikelnummer: TGM-T8527-100mg
Description: CPYPP is an inhibitor of DOCK2-Rac1 interaction. CPYPP binds to DOCK2 DHR-2 domain and inhibits the guanine nucleotide exchange factor (GEF) activity of DOCK2DHR-2 for Rac1 in a dose-dependent manner(IC50 : 22.8 µM). CPYPP also inhibits DOCK180, DOCK5 and less DOCK9. Target: Others. Smiles:...
| Anwendung: | DOCK2 / DOCK5 / DOCK180 inhibitor |
| CAS | 310460-39-0 |
| MW: | 324.76 D |
ab 38,00 €
Artikelnummer: G-AGMB06217.100
DOCK2 Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF),...
| Schlagworte: | Anti-DOCK2, Anti-Dedicator of cytokinesis protein 2 |
| Anwendung: | IHC-P |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 353,00 €
Artikelnummer: G-AGMB00481.100
DOCK2 Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF),...
| Schlagworte: | Anti-DOCK2, Anti-Dedicator of cytokinesis protein 2 |
| Anwendung: | WB, IHC-P |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 134,00 €
Artikelnummer: G-AGMB02099.100
DOCK2 Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF),...
| Schlagworte: | Anti-DOCK2, Anti-Dedicator of cytokinesis protein 2 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 134,00 €
Artikelnummer: ABS-RC-16245.100
Protein function: Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation...
| Schlagworte: | Anti-DOCK2, Anti-KIAA0209, Anti-Dedicator of cytokinesis protein 2 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 206,00 €
Artikelnummer: ABS-PP-10659-L.100
Protein function: Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation...
| Schlagworte: | Dedicator of cytokinesis protein 2, Recombinant Human DOCK2 Protein |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 12.5 kD |
ab 115,00 €
Artikelnummer: D8080-05M.100
DOCK2 (Dedicator of cytokinesis protein 2) is a member of the DOCK-A family, DOCK180 superfamily of proteins. Its predicted molecular weight is 210kD, although it may run approximately at 190kD in SDS-PAGE. It is found in hematopoietic cell types, and regulates the activity of the GTPases Rac-1 and -2. Human DOCK2...
| Schlagworte: | Anti-Dedicator of cytokinesis protein 2 |
| Anwendung: | WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | goat, human |
1.039,00 €