Zu "K12351" wurden 42 Artikel gefunden!
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NEU
Recombinant yeast SUMO Protease
Artikelnummer: SCC-MB9018
SUMO (Small Ubiquitin-like MOdifiers) Protease 1 (Ulp1, UBI-specific protease 1 from Saccharomyces cerevisiae) is a highly active cysteine protease. Rather than recognizing a short sequence such as TEV, Thrombin or Enterokinease, SUMO protease specifically recognizes the tertiary structure of the hSUMO1-3 and yeast...
| Schlagworte: | rScUlp1, ISC1, Neutral sphingomyelinase, Inositol phosphosphingolipids phospholipase C |
ab 263,00 €
Human NSMASE (Neutral Sphingomyelinase) Microsample ELISA...
Artikelnummer: ELK-ELK3304MS.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human NSMASE. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human NSMASE....
| Schlagworte: | SMPD2, Neutral sphingomyelinase, Sphingomyelin phosphodiesterase 2, Lyso-platelet-activating factor-phospholipase C |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 374,00 €
Rat NSMASE (Neutral Sphingomyelinase) Microsample ELISA Kit
Artikelnummer: ELK-ELK6191MS.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat NSMASE. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat NSMASE. Next,...
| Schlagworte: | Smpd2, Neutral sphingomyelinase, Sphingomyelin phosphodiesterase 2, Lyso-platelet-activating factor-phospholipase C |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 374,00 €
GW 4869 (hydrochloride hydrate)
Artikelnummer: Cay13127-1
Neutral sphingomyelinases mediate the release of ceramide from sphingomyelin in cellular membranes and can be activated by certain stresses. Ceramide can act as a signaling molecule in its own right, or it can be further processed to generate sphingosine (and sphingosine-1-phosphate). GW 4869 is an inhibitor of...
| Schlagworte: | 3,3'-(1,4-phenylene)bis[N-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-dihydrochloride-2-propenamide |
| Anwendung: | Neutral sphingomyelinase inhibitor |
| CAS | 6823-69-4 |
| MW: | 577.5 D |
ab 55,00 €
Altenusin
Artikelnummer: AG-CN2-0143-M001
Isolated from Penicillium sp. Antibiotic. Antifungal penicillide. Non-competitive, specific neutral sphingomyelinase (N-SMase) inhibitor. Strong pp60c-Src inhibitor. Inhibits cFMS receptor tyrosine kinase (CSF-1/m-CSF receptor tyrosine kinase) which is implicated in cancer and bone diseases. Myosin light chain...
| Schlagworte: | MS 341 |
| Anwendung: | N-SMase inhibitor |
| CAS | 31186-12-6 |
| MW: | 290,3 D |
ab 154,00 €
GW4869
Artikelnummer: TGM-T3640-5mg
Description: GW4869 (GW69A) is a selective and non-competitive inhibitor of neutral sphingomyelinase N-SMase (IC50=1 µM). GW4869 also inhibits exosome synthesis/release and is commonly used in exosome-related studies.Usually prepared as a suspension for experiments. Target: Phospholipase. Smiles:...
| Schlagworte: | GW554869A , GW69A , GW 4869 |
| Anwendung: | Neutral sphingomyelinase inhibitor |
| CAS | 6823-69-4 |
| MW: | 577.5 D |
ab 64,00 €
Anti-SMPD2 / nSMase
Artikelnummer: ARG59500.100
Protein function: Converts sphingomyelin to ceramide. Hydrolyze 1-acyl-2- lyso-sn-glycero-3-phosphocholine (lyso-PC) and 1-O-alkyl-2-lyso- sn-glycero-3-phosphocholine (lyso-platelet-activating factor). The physiological substrate seems to be Lyso-PAF. [The UniProt Consortium]
| Schlagworte: | Anti-SMPD2, Anti-nSMase, Anti-N-SMase, EC=3.1.4.12, Anti-Lyso-PAF-PLC, Anti-Neutral sphingomyelinase, Anti-Sphingomyelin... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse, rat |
707,00 €
Anti-SMPD2 / nSMase
Artikelnummer: ARG59535.100
Protein function: Converts sphingomyelin to ceramide. Hydrolyze 1-acyl-2- lyso-sn-glycero-3-phosphocholine (lyso-PC) and 1-O-alkyl-2-lyso- sn-glycero-3-phosphocholine (lyso-platelet-activating factor). The physiological substrate seems to be Lyso-PAF. [The UniProt Consortium]
| Schlagworte: | Anti-SMPD2, Anti-nSMase, Anti-N-SMase, EC=3.1.4.12, Anti-Lyso-PAF-PLC, Anti-Neutral sphingomyelinase, Anti-Sphingomyelin... |
| Anwendung: | FC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
616,00 €
Anti-SMPD2
Artikelnummer: E-AB-19030.120
This gene encodes a protein which was initially identified as a sphingomyelinase based on sequence similarity between bacterial sphingomyelinases and a yeast protein. Subsequent studies showed that its biological function is less likely to be as a sphingomyelinase and instead as a lysophospholipase. Protein...
| Schlagworte: | Anti-SMPD2, Anti-nSMase, Anti-N-SMase, EC=3.1.4.12, Anti-Lyso-PAF-PLC, Anti-Neutral sphingomyelinase, Anti-Sphingomyelin... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Anti-SMPD2
Artikelnummer: E-AB-52945.120
This gene encodes a protein which was initially identified as a sphingomyelinase based on sequence similarity between bacterial sphingomyelinases and a yeast protein. Subsequent studies showed that its biological function is less likely to be as a sphingomyelinase and instead as a lysophospholipase. Protein...
| Schlagworte: | Anti-SMPD2, Anti-nSMase, Anti-N-SMase, EC=3.1.4.12, Anti-Lyso-PAF-PLC, Anti-Neutral sphingomyelinase, Anti-Sphingomyelin... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Anti-SMPD2
Artikelnummer: ATA-HPA018125.100
Protein function: Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Hydrolyze...
| Schlagworte: | Anti-nSMase, Anti-N-SMase, Anti-nSMase1, Anti-Lyso-PAF-PLC, Anti-Neutral sphingomyelinase, Anti-Sphingomyelin... |
| Anwendung: | ICC, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 246,00 €
Rat NSMASE (Neutral Sphingomyelinase) ELISA Kit
Artikelnummer: ELK-ELK6191.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat NSMASE. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat NSMASE. Next,...
| Schlagworte: | Smpd2, nSMase, N-SMase, EC=3.1.4.12, Lyso-PAF-PLC, Neutral sphingomyelinase, Sphingomyelin phosphodiesterase 2,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 374,00 €