Zu "K12344" wurden 33 Artikel gefunden!
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Finasteride
Artikelnummer: Cay14938-50
Finasteride is a 4-azasteroid competitive inhibitor of 5alpha-reductase type II (IC50 = 4.2 nM) and a derivative of testosterone. It is 100-fold selective for 5alpha-reductase type II over type I. Finasteride (10 µM) does not affect the growth of androgen-refractory PC3 prostate cancer cells but increases the...
| Schlagworte: | MK-906,... |
| Anwendung: | Type II 5alpha-reductase inhibitor |
| CAS | 98319-26-7 |
| MW: | 372.5 D |
ab 56,00 €
Elaiophylin
Artikelnummer: BVT-0185-M001
Antibiotic, Active against Gram-positive bacteria, protozoa and tumors, Testosterone 5alpha-reductase inhibitor, Nitric oxide synthase (NOS) inhibitor, Immunosuppressive, Enhances the antifungal activity of rapamycin. Isolated from Streptomyces sp. MT-1.
| Schlagworte: | Antibiotic 255-E, Antibiotic 5001B, Antibiotic 56-62, Antibiotic 846I, SNA 4606-3, Gopalamicin, Salbomycin, Azalomycin B |
| Anwendung: | Testosterone 5alpha-reductase inhibitor, Nitric oxide synthase (NOS) inhibitor |
| CAS | 37318-06-2 |
| MW: | 1025,3 D |
105,00 €
Finasteride
Artikelnummer: AG-CR1-3589-M025
White to off-white solid. Soluble in DMSO, DMF, ethanol or methanol. Sparingly soluble in water. Potent, specific and competitive inhibitor of type II 5alpha-reductase (enzyme which converts testosterone to the more potent 5alpha-dihydrotestosterone), Anticancer compound, Apoptosis modulator, Enhances the action of...
| Schlagworte: | MK 906, L-652,931, BRN 4269024 |
| Anwendung: | Type II 5alpha-reductase inhibitor |
| CAS | 98319-26-7 |
| MW: | 372,5 D |
ab 17,00 €
Pantoprazole-d6
Artikelnummer: Cay28483-1
Pantoprazole-d6 is intended for use as an internal standard for the quantification of pantoprazole (Cay-21345) by GC- or LC-MS. Pantoprazole is a proton pump inhibitor that inhibits H+/K+-ATPase activity in porcine gastric membrane vesicles with an IC50 value of 6.8 µM. It reduces basal gastric acid secretion in...
| Schlagworte: | 6-(difluoromethoxy)-2-[[[3,4-di(methoxy-d3)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole |
| Anwendung: | GC-MS, LC-MS, internal standard, quantification, type II 5alpha-reductase inhibitor |
| CAS | 922727-65-9 |
| MW: | 389.4 D |
720,00 €
Anti-SRD5A2 / 5-alpha reductase 2, N-terminal
Artikelnummer: ARG63698.100
Protein function: Converts testosterone (T) into 5-alpha- dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology. [The UniProt Consortium]
| Schlagworte: | Anti-SRD5A2, Anti-S5AR 2, Anti-SR type 2, EC=1.3.1.22, Anti-5 alpha-SR2, Anti-Type II 5-alpha reductase, Anti-Steroid... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Anti-SRD5A2, C-terminal
Artikelnummer: ARG64868.100
Protein function: Converts testosterone (T) into 5-alpha- dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology. [The UniProt Consortium]
| Schlagworte: | Anti-SRD5A2, Anti-S5AR 2, Anti-SR type 2, EC=1.3.1.22, Anti-5 alpha-SR2, Anti-Type II 5-alpha reductase, Anti-Steroid... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Dutasteride
Artikelnummer: LKT-D8276.25
5-alpha-Reductase inhibitor.
| Schlagworte: | Avodart |
| Anwendung: | 5alpha-reductase 1 inhibitor, 5alpha-reductase 2 inhibitor |
| CAS | 164656-23-9 |
| MW: | 528.53 D |
ab 176,00 €
Anti-SRD5A2
Artikelnummer: NSJ-R34532-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Steroid 5 alpha-reductase 2 Protein function: Converts testosterone (T) into 5-alpha- dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids....
| Schlagworte: | Anti-S5AR 2, Anti-SRD5A2, Anti-SR type 2, Anti-5 alpha-SR2, EC=1.3.1.22, Anti-Type II 5-alpha reductase, Anti-Steroid... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
Anti-SRD5A2
Artikelnummer: NSJ-R35507-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Steroid-5-alpha-reductase, alpha polypeptide 2 Protein function: Converts testosterone (T) into 5-alpha- dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding...
| Schlagworte: | Anti-S5AR 2, Anti-SRD5A2, Anti-SR type 2, Anti-5 alpha-SR2, EC=1.3.1.22, Anti-Type II 5-alpha reductase, Anti-Steroid... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
Dutasteride
Artikelnummer: Cay15956-50
Dutasteride is a dual inhibitor of 5alpha-reductase types I and II (Kis = 6 and 7 nM, respectively). Its inhibition is time-dependent inhibitor with apparent Ki values of 17 and 4.3 nM at 10- and 30-minute reaction times, respectively. Dutasteride decreases prostate weight in a rat model of benign prostatic...
| Schlagworte: | N-[2,5-bis(trifluoromethyl)phenyl]-2,4aR,4bS,5,6,6aS,7S,8,9,9aS,9bS,10,11,11aR-tetradecahydro-4a,6a-dimethyl-2-oxo-1H-inde... |
| Anwendung: | 5alpha-reductase 1 / 2 inhibitor |
| CAS | 164656-23-9 |
| MW: | 528.5 D |
ab 102,00 €
Finasteride
Artikelnummer: LKT-F3354.100
Finasteride is a synthetic 4-azasteroid. It is a specific inhibitor of the enzyme steroid 5-alpha-reductase which is responsible for the conversion of testosterone into the potent androgen 5alpha-dihydrotestosterone.
| Anwendung: | Steroid 5-alpha-reductase inhibitor |
| CAS | 98319-26-7 |
| MW: | 372,54 D |
ab 187,00 €
Finasteride-d9
Artikelnummer: Cay28482-1
Finasteride-d9 is intended for use as an internal standard for the quantification of finasteride (Cay-14938) by GC- or LC-MS. Finasteride is a 4-azasteroid competitive inhibitor of 5alpha-reductase type II (IC50 = 4.2 nM) and a derivative of testosterone. It is 100-fold selective for 5alpha-reductase type II over...
| Schlagworte: | (4aR,4bS,6aS,7S,9aS,9bS,11aR)-4a,6a-dimethyl-N-(2-(methyl-d3)propan-2-yl-1,1,1,3,3,3-d6)-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,... |
| Anwendung: | GC-MS, LC-MS, internal standard, quantification, type II 5alpha-reductase inhibitor |
| CAS | 1131342-85-2 |
| MW: | 381.6 D |
ab 235,00 €