Zu "K12316" wurden 60 Artikel gefunden!
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Hericerin
Artikelnummer: Cay39057-1
An isoindolinone with diverse biological activities, inhibits alpha-glucosidase (IC50 = 5.3 µM), cytotoxic to A549 and HeLa cancer cells (IC50s = 49 and 40.5 µM, respectively), induces neurite outgrowth in Neuro2a cells at 25 µM, increases NGF production in C6 cells at 50 µM. Formulation: A solid. InChI:...
| Schlagworte: | Isohericerin, 5-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-2,3-dihydro-4-hydroxy-6-methoxy-2-(2-phenylethyl)-1H-isoindol-1-one |
| Anwendung: | Bioactive isoindolinone |
| CAS | 140381-53-9 |
| MW: | 419.56 D |
ab 89,00 €
Castanospermine
Artikelnummer: Cay11313-5
Glucosidases catalyze the cleavage of individual glucosyl residues from various glycoconjugates, including complex carbohydrates and glycoproteins. Castanospermine is an inhibitor of both alpha- and beta-glucosidases, inhibiting lysosomal and neutral alpha-glucosidases with Ki values of 0.1 and 10 µM, respectively,...
| Schlagworte: | 1,6,7,8-Tetrahydroxyoctahydroindolizine, 6,7-Diepicastanospermine, 6-Epicastanospermine, NSC 625381,... |
| Anwendung: | Glycosidase inhibitor |
| CAS | 79831-76-8 |
| MW: | 189.2 D |
ab 65,00 €
Miglitol
Artikelnummer: Cay15014-50
Miglitol is an inhibitor of alpha-glucosidases (IC50s = 0.35, 0.11, 1.3, and 1.2 µM for human lysosomal alpha-glucosidase and rat sucrase, maltase, and isomaltase, respectively). It is selective for human alpha- over beta-glucosidase (IC50 = 84 µM). Miglitol (10 mg/kg) decreases blood glucose levels in...
| Schlagworte: | BAY-1099, Diastabol, Glyset, Seibule, 1-(2-hydroxyethyl)-2R-(hydroxymethyl)-3R,4R,5S-piperidinetriol |
| Anwendung: | alpha-glucosidase inhibitor |
| CAS | 72432-03-2 |
| MW: | 207.2 D |
ab 122,00 €
Miglitol
Artikelnummer: AG-CR1-3635-M010
White solid. Soluble in water or DMSO. Anti-diabetic agent with antihyperglycemic activity. alpha-Glucosidase inhibitor. Inhibits lysosomal alpha-glucosidase, sucrase, maltase and isomaltase (IC50= 0.35, 0.11, 1.3, and 1.2&mu,M, respectively) as well as maltase-glucoamylase (IC50 = 1.0&mu,M), alpha-Glucosidase...
| Schlagworte: | (2R,3R,4R,5S)-1-(2-Hydroxyethyl)-2-(2-hydroxymethyl)-3,4,5-piperidinetriol, BAY-1099, Diastabol, Glyset, Seibule |
| Anwendung: | alpha-Glucosidase inhibitor |
| CAS | 72432-03-2 |
| MW: | 207,2 D |
ab 44,00 €
Deoxynojirimycin
Artikelnummer: BVT-0112-M001
Soluble in DMSO or water. Isolated from Streptomyces sp. Polyhydroxylated piperidine alkaloid. alpha-Glucosidase I and II inhibitor. Antidiabetic. Antihyperglycaemic activity. Animal feedstuff additive. Antiviral. Shows anti-HIV activity.
| Schlagworte: | 1,5-Dideoxy-1,5-imino-D-glucitol, Moranoline, DNJ |
| Anwendung: | alpha-glucosidase inhibitor |
| CAS | 19130-96-2 |
| MW: | 163,2 D |
ab 20,00 €
Resorufin alpha-D-glucopyranoside
Artikelnummer: ABD-14022
Ex: 571 nm. Em: 585 nm. Soluble in: DMSO. Resorufin alpha-D-glucopyranoside is a sensitive fluorogenic substrate that generates a red fluorescent product (resorufin) upon interaction with alpha-glucosidase. It is used for measuring alpha-glucosidase activities and high throughput screening of alpha-glucosidase...
| Anwendung: | Fluorogenic alpha-glucosidase substrate |
| CAS | 136565-96-3 |
| MW: | 375,33 D |
554,00 €
Human Lysosomal alpha-Glucosidase / GAA ELISA Kit
Artikelnummer: G-HUFI00534.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Mouse Lysosomal alpha-Glucosidase / GAA ELISA Kit
Artikelnummer: G-MOFI00197.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
698,00 €
Voglibose
Artikelnummer: Cay14179-100
Voglibose is an inhibitor of alpha-glucosidases (IC50s = 5.6, 0.11, 0.16, and 0.07 µM for human lysosomal alpha-glucosidase and rat maltase, isomaltase, and sucrase, respectively). It is selective for human alpha- over beta-glucosidase (IC50 = >1,000 µM). Voglibose (0.2 mg/kg) decreases body weight and food intake...
| Schlagworte: | AO-128, 3,4-dideoxy-4-[[2-hydroxy-1-(hydroxymethyl)ethyl]amino]-2-C-(hydroxymethyl)-D-epi-inositol |
| Anwendung: | alpha-glucosidase inhibitor |
| CAS | 83480-29-9 |
| MW: | 267.3 D |
ab 49,00 €
alpha Glucosidase Activity Assay Kit (Colorimetric)
Artikelnummer: ARG82166.100
Protein function: Essential for the degradation of glycogen in lysosomes (PubMed:1856189, PubMed:7717400, PubMed:14695532, PubMed:18429042). Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans (PubMed:29061980). [The UniProt Consortium]
| Schlagworte: | GAA |
| Anwendung: | Detection, Quantification |
| Spezies-Reaktivität: | human, mouse, rat |
1.299,00 €
4-Methylumbelliferyl-alpha-D-Glucopyranoside
Artikelnummer: Cay26810-100
4-Methylumbelliferyl-alpha-D-glucopyranoside is a fluorogenic substrate for alpha-glucosidase. 4-Methylumbelliferyl-alpha-D-glucopyranoside is cleaved by alpha-glucosidase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low...
| Schlagworte: | 4-Methylumbelliferyl-alpha-D-Glucose, 4-Methylumbelliferyl-alpha-D-Glucoside, 4-MU-alpha-D-Glucopyranoside,... |
| Anwendung: | Fluorogenic alpha-glucosidase substrate |
| CAS | 17833-43-1 |
| MW: | 338.3 D |
ab 67,00 €
Anti-GAA
Artikelnummer: ARG58730.100
Protein function: Essential for the degradation of glycogen in lysosomes (PubMed:1856189, PubMed:7717400, PubMed:14695532, PubMed:18429042). Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans (PubMed:29061980). [The UniProt Consortium]
| Schlagworte: | Anti-GAA |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
707,00 €