Zu "K12316" wurden 55 Artikel gefunden!
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Castanospermine
Artikelnummer: TGM-TQ0308-10mg
Description: Castanospermine (1,6,7,8-Tetrahydroxyoctahydroindolizine) is a natural compound that inhibits alpha- and beta-glucosidases, especially glucosidase l. Target: Glucosidase. Smiles: OC1CCN2CC(O)C(O)C(O)C12. References: Bryan G, Anthony C et al. The structural basis of the inhibition of human glycosidases...
| Schlagworte: | (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine, 1,6,7,8-Tetrahydroxyoctahydroindolizine |
| Anwendung: | Glycosidase inhibitor |
| CAS | 79831-76-8 |
| MW: | 189.21 D |
ab 33,00 €
N-Nonyldeoxynojirimycin
Artikelnummer: TGM-TP1080-10mg
Description: N-Nonyldeoxynojirimycin (NN-DNJ) is an inhibitor of acid alpha-glucosidase and alpha-1,6-glucosidase with IC50 values of 0.42 µM and 8.4 µM, respectively. Smiles: CCCCCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO. References: Andersson U, et al. Inhibition of glycogen breakdown by imino sugars in vitro and...
| Schlagworte: | NN-DNJ, Nonyl-DNJ |
| Anwendung: | Acid alpha-glucosidase inhibitor, alpha-1,6-glucosidase inhibitor |
| CAS | 81117-35-3 |
| MW: | 289.41 D |
ab 88,00 €
2,3-Indolobetulonic Acid
Artikelnummer: TGM-T37782-10mg
Description: 2,3-Indolobetulonic acid is pentacyclic triterpenoid derivative of betulonic acid and an inhibitor of alpha-glucosidase (IC50= 1.8 µM).1. Target: Others. Smiles: [H][C@]12[C@@H](CC[C@@]1(CC[C@]1(C)[C@]2([H])CC[C@]2([H])[C@@]3(C)Cc4c([nH]c5ccccc45)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O)C(C)=C. References:...
| Anwendung: | alpha-glucosidase inhibitor |
| CAS | 905837-93-6 |
| MW: | 527.793 D |
ab 77,00 €
1-Deoxynojirimycin
Artikelnummer: TGM-T3675-100mg
Description: 1-Deoxynojirimycin (Moranoline) is a potent alpha-glucosidase inhibitor, suppressing postprandial blood glucose, thereby possibly preventing diabetes mellitus. Target: Glucosidase, PI3K. Smiles: OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O. References: Jiang P, et al. Sci Rep. 2015 Feb 24,5:8563.
| Schlagworte: | moranolin, Moranoline, Duvoglustat |
| Anwendung: | Targets lysosomal alpha-glucosidase [EC:3.2.1.20] (GAA) |
| CAS | 19130-96-2 |
| MW: | 163.17 D |
ab 40,00 €
4-Methylumbelliferyl-alpha-D-Glucopyranoside
Artikelnummer: TGM-T85134-10mg
Description: 4-Methylumbelliferyl-alpha-D-glucopyranoside serves as a fluorogenic substrate for alpha-glucosidase, used in enzymatic assays. This compound undergoes cleavage by alpha-glucosidase, releasing 4-methylumbelliferyl (4-MU), a compound whose fluorescence intensity varies with pH. Specifically, 4-MU...
| Schlagworte: | 4-Methylumbelliferyl-alpha-D-Glucose, 4-Methylumbelliferyl-alpha-D-Glucoside, 4-MU-alpha-D-Glucopyranoside |
| Anwendung: | Fluorogenic alpha-glucosidase substrate |
| CAS | 17833-43-1 |
| MW: | 338.312 D |
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Castanospermine
Artikelnummer: Cay11313-5
Glucosidases catalyze the cleavage of individual glucosyl residues from various glycoconjugates, including complex carbohydrates and glycoproteins. Castanospermine is an inhibitor of both alpha- and beta-glucosidases, inhibiting lysosomal and neutral alpha-glucosidases with Ki values of 0.1 and 10 µM, respectively,...
| Schlagworte: | 1,6,7,8-Tetrahydroxyoctahydroindolizine, 6,7-Diepicastanospermine, 6-Epicastanospermine, NSC 625381,... |
| Anwendung: | Glycosidase inhibitor |
| CAS | 79831-76-8 |
| MW: | 189.2 D |
ab 59,00 €
Miglitol
Artikelnummer: Cay15014-50
Miglitol is an inhibitor of alpha-glucosidases (IC50s = 0.35, 0.11, 1.3, and 1.2 µM for human lysosomal alpha-glucosidase and rat sucrase, maltase, and isomaltase, respectively). It is selective for human alpha- over beta-glucosidase (IC50 = 84 µM). Miglitol (10 mg/kg) decreases blood glucose levels in...
| Schlagworte: | BAY-1099, Diastabol, Glyset, Seibule, 1-(2-hydroxyethyl)-2R-(hydroxymethyl)-3R,4R,5S-piperidinetriol |
| Anwendung: | alpha-glucosidase inhibitor |
| CAS | 72432-03-2 |
| MW: | 207.2 D |
ab 111,00 €
Miglitol
Artikelnummer: AG-CR1-3635-M010
White solid. Soluble in water or DMSO. Anti-diabetic agent with antihyperglycemic activity. alpha-Glucosidase inhibitor. Inhibits lysosomal alpha-glucosidase, sucrase, maltase and isomaltase (IC50= 0.35, 0.11, 1.3, and 1.2&mu,M, respectively) as well as maltase-glucoamylase (IC50 = 1.0&mu,M), alpha-Glucosidase...
| Schlagworte: | (2R,3R,4R,5S)-1-(2-Hydroxyethyl)-2-(2-hydroxymethyl)-3,4,5-piperidinetriol, BAY-1099, Diastabol, Glyset, Seibule |
| Anwendung: | alpha-Glucosidase inhibitor |
| CAS | 72432-03-2 |
| MW: | 207,2 D |
ab 72,00 €
Deoxynojirimycin
Artikelnummer: BVT-0112-M001
Soluble in DMSO or water. Isolated from Streptomyces sp. Polyhydroxylated piperidine alkaloid. alpha-Glucosidase I and II inhibitor. Antidiabetic. Antihyperglycaemic activity. Animal feedstuff additive. Antiviral. Shows anti-HIV activity.
| Schlagworte: | 1,5-Dideoxy-1,5-imino-D-glucitol, Moranoline, DNJ |
| Anwendung: | alpha-glucosidase inhibitor |
| CAS | 19130-96-2 |
| MW: | 163,2 D |
ab 20,00 €
Resorufin alpha-D-glucopyranoside
Artikelnummer: ABD-14022
Ex: 571 nm. Em: 585 nm. Soluble in: DMSO. Resorufin alpha-D-glucopyranoside is a sensitive fluorogenic substrate that generates a red fluorescent product (resorufin) upon interaction with alpha-glucosidase. It is used for measuring alpha-glucosidase activities and high throughput screening of alpha-glucosidase...
| Anwendung: | Fluorogenic alpha-glucosidase substrate |
| CAS | 136565-96-3 |
| MW: | 375,33 D |
542,00 €
Human Lysosomal alpha-Glucosidase / GAA ELISA Kit
Artikelnummer: G-HUFI00534.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €
Mouse Lysosomal alpha-Glucosidase / GAA ELISA Kit
Artikelnummer: G-MOFI00197.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
694,00 €