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Zu "K11988" wurden 151 Artikel gefunden!
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NEU
Artikelnummer: ELK-ELK6289MS.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat SHH. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat SHH. Next, Avidin...
| Schlagworte: | Shh, Sonic hedgehog protein, Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 374,00 €
NEU
Artikelnummer: ELK-ELK2215MS.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human SHH. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human SHH. Next,...
| Schlagworte: | Shh, HHG-1, Sonic hedgehog protein, Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 374,00 €
NEU
Artikelnummer: ELK-ELK0379MS.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse SHH. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse SHH. Next,...
| Schlagworte: | Shh, HHG-1, Sonic hedgehog protein, Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 374,00 €
Artikelnummer: 97290.25
Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also regulates another target, the gli oncogene. Intercellular signal essential for a variety of...
| Schlagworte: | SHH, HHG-1, HHG1, Sonic hedgehog protein, TPT, HLP3, HPE3, SMMCI, TPTPS, MCOPCB5 |
| Anwendung: | Cell culture |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 19683 D |
ab 105,00 €
Artikelnummer: NSJ-FY13406
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Sonic Hedgehog antibody targets Sonic Hedgehog (SHH), a secreted signaling protein that functions as a key morphogen controlling embryonic development and tissue patterning. SHH is synthesized as a...
| Schlagworte: | Anti-Shh, Anti-HHG-1, Anti-Sonic hedgehog protein, Anti-Shh unprocessed N-terminal signaling and C-terminal autoprocessing... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Artikelnummer: E-AN301249L.100
This gene encodes a protein that is instrumental in patterning the early embryo. It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. Of three human proteins showing sequence and functional similarity to the sonic...
| Schlagworte: | Anti-SHH, Anti-HHG-1, Anti-Sonic hedgehog protein, Anti-Shh unprocessed N-terminal signaling and C-terminal autoprocessing... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 257,00 €
Artikelnummer: NSJ-RZ1309
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Zebrafish Shha, also known as sonic hedgehog a, is a signaling molecule that plays a critical role in embryonic development, pattern formation, and cell differentiation. Shha belongs to the hedgehog family of secreted proteins that regulate key developmental...
| Schlagworte: | Anti-shha, Anti-VHH-1, Anti-Sonic hedgehog protein, Anti-Shh unprocessed N-terminal signaling and C-terminal... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | zebrafish |
948,00 €
Artikelnummer: 08546.5
Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also regulates another target, the gli oncogene. Intercellular signal essential for a variety of...
| Schlagworte: | SHH, HHG-1, HHG1, Sonic hedgehog protein |
| Anwendung: | Cell culture |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 19800.00 D |
ab 105,00 €
Artikelnummer: Cay10008672-250
Celecoxib is a non-steroidal anti-inflammatory drug (NSAID) and COX-2 inhibitor (IC50 = 0.05 µM). It is selective for COX-2 over COX-1 (IC50 = 22.9 µM). Celecoxib induces apoptosis in BJAB and Jurkat cancer cells in a concentration-dependent manner. It reduces blood glucose levels in a rat model of diabetes induced...
| Schlagworte: | SC-58635, YM-177, 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-benzenesulfonamide |
| Anwendung: | COX-2 inhibitor |
| CAS | 169590-42-5 |
| MW: | 381.4 D |
ab 60,00 €
Artikelnummer: BPS-91012
Mouse sonic hedgehog (mShh), also known as HHG-1. GenBank Accession No. NM_009170, a.a. 25-198 with a C-terminal His-tag, expressed in an E. coli cell expression system, MW = 20.5 kDa.
| Schlagworte: | Hhg1, |
| Anwendung: | Binding assays, small molecule screening, immunogen |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 20.5 kD |
340,00 €
Artikelnummer: Cay13204-1
Sonic hedgehog (Shh) is the most widely characterized of the three vertebrate Hedgehog homologs, and is essential for proper embryonic development. Shh binds to its receptor, Patched (Ptch1), resulting in the de-repression of Smoothened. This leads to the activation of Gli2, which regulates the transcription of...
| Schlagworte: | N-[(4-chlorophenyl)methyl]-5,12-dioxo-2R-phenyl-1-oxa-4-azacyclododec-8E-ene-6S-acetamide |
| Anwendung: | Shh inhibitor |
| CAS | 1132653-79-2 |
| MW: | 455 D |
520,00 €
Artikelnummer: Cay15400-5
Zerumbone is a natural monocyclic sesquiterpene first isolated from rhizomes of the wild ginger Z. zerumbet. It potently inhibits the activation of Epstein-Barr virus by phorbol esters (IC50 = 140 nM). Zerumbone inhibits Sonic hedgehog signaling and induces apoptosis in cancer cell lines. It has also been shown to...
| Schlagworte: | (2E,6E)-2,6,9,9-tetramethyl-2,6,10E-cycloundecatrien-1-one |
| Anwendung: | Sonic hedgehog signaling inhibitor, apoptosis inducer |
| CAS | 471-05-6 |
| MW: | 218.3 D |
ab 59,00 €