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NEU
Rat SHH (Hedgehog Homolog, Sonic) Microsample ELISA Kit
Rat SHH (Hedgehog Homolog, Sonic) Microsample ELISA Kit

Artikelnummer: ELK-ELK6289MS.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat SHH. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat SHH. Next, Avidin...
Schlagworte: Shh, Sonic hedgehog protein, Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains
Anwendung: ELISA
Spezies-Reaktivität: rat
ab 374,00 €
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NEU
Human SHH (Hedgehog Homolog, Sonic) Microsample ELISA Kit
Human SHH (Hedgehog Homolog, Sonic) Microsample ELISA Kit

Artikelnummer: ELK-ELK2215MS.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human SHH. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human SHH. Next,...
Schlagworte: Shh, HHG-1, Sonic hedgehog protein, Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains
Anwendung: ELISA
Spezies-Reaktivität: human
ab 374,00 €
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NEU
Mouse SHH (Sonic Hedgehog Homolog) Microsample ELISA Kit
Mouse SHH (Sonic Hedgehog Homolog) Microsample ELISA Kit

Artikelnummer: ELK-ELK0379MS.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse SHH. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse SHH. Next,...
Schlagworte: Shh, HHG-1, Sonic hedgehog protein, Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains
Anwendung: ELISA
Spezies-Reaktivität: mouse
ab 374,00 €
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Sonic HedgeHog, human recombinant (rHuSHH)
Sonic HedgeHog, human recombinant (rHuSHH)

Artikelnummer: 97290.25

Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also regulates another target, the gli oncogene. Intercellular signal essential for a variety of...
Schlagworte: SHH, HHG-1, HHG1, Sonic hedgehog protein, TPT, HLP3, HPE3, SMMCI, TPTPS, MCOPCB5
Anwendung: Cell culture
Exprimiert in: E.coli
Ursprungsart: human
MW: 19683 D
ab 105,00 €
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Anti-SHH / Sonic Hedgehog, clone ABE-19
Anti-SHH / Sonic Hedgehog, clone ABE-19

Artikelnummer: NSJ-FY13406

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Sonic Hedgehog antibody targets Sonic Hedgehog (SHH), a secreted signaling protein that functions as a key morphogen controlling embryonic development and tissue patterning. SHH is synthesized as a...
Schlagworte: Anti-Shh, Anti-HHG-1, Anti-Sonic hedgehog protein, Anti-Shh unprocessed N-terminal signaling and C-terminal autoprocessing...
Anwendung: WB, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
790,00 €
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Anti-Recombinant Shh, clone 2D9
Anti-Recombinant Shh, clone 2D9

Artikelnummer: E-AN301249L.100

This gene encodes a protein that is instrumental in patterning the early embryo. It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. Of three human proteins showing sequence and functional similarity to the sonic...
Schlagworte: Anti-SHH, Anti-HHG-1, Anti-Sonic hedgehog protein, Anti-Shh unprocessed N-terminal signaling and C-terminal autoprocessing...
Anwendung: IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 257,00 €
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Anti-Zebrafish Shha / Shh / Sonic Hedgehog
Anti-Zebrafish Shha / Shh / Sonic Hedgehog

Artikelnummer: NSJ-RZ1309

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Zebrafish Shha, also known as sonic hedgehog a, is a signaling molecule that plays a critical role in embryonic development, pattern formation, and cell differentiation. Shha belongs to the hedgehog family of secreted proteins that regulate key developmental...
Schlagworte: Anti-shha, Anti-VHH-1, Anti-Sonic hedgehog protein, Anti-Shh unprocessed N-terminal signaling and C-terminal...
Anwendung: WB, IHC (paraffin)
Wirt: Rabbit
Spezies-Reaktivität: zebrafish
948,00 €
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Sonic Hedgehog, mouse recombinant (rmSHH)
Sonic Hedgehog, mouse recombinant (rmSHH)

Artikelnummer: 08546.5

Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also regulates another target, the gli oncogene. Intercellular signal essential for a variety of...
Schlagworte: SHH, HHG-1, HHG1, Sonic hedgehog protein
Anwendung: Cell culture
Exprimiert in: E.coli
Ursprungsart: mouse
MW: 19800.00 D
ab 105,00 €
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Celecoxib
Celecoxib

Artikelnummer: Cay10008672-250

Celecoxib is a non-steroidal anti-inflammatory drug (NSAID) and COX-2 inhibitor (IC50 = 0.05 µM). It is selective for COX-2 over COX-1 (IC50 = 22.9 µM). Celecoxib induces apoptosis in BJAB and Jurkat cancer cells in a concentration-dependent manner. It reduces blood glucose levels in a rat model of diabetes induced...
Schlagworte: SC-58635, YM-177, 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-benzenesulfonamide
Anwendung: COX-2 inhibitor
CAS 169590-42-5
MW: 381.4 D
ab 60,00 €
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Mouse Sonic Hedgehog (Shh), His-tag
Mouse Sonic Hedgehog (Shh), His-tag

Artikelnummer: BPS-91012

Mouse sonic hedgehog (mShh), also known as HHG-1. GenBank Accession No. NM_009170, a.a. 25-198 with a C-terminal His-tag, expressed in an E. coli cell expression system, MW = 20.5 kDa.
Schlagworte: Hhg1,
Anwendung: Binding assays, small molecule screening, immunogen
Exprimiert in: E.coli
Ursprungsart: mouse
MW: 20.5 kD
340,00 €
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Robotnikinin
Robotnikinin

Artikelnummer: Cay13204-1

Sonic hedgehog (Shh) is the most widely characterized of the three vertebrate Hedgehog homologs, and is essential for proper embryonic development. Shh binds to its receptor, Patched (Ptch1), resulting in the de-repression of Smoothened. This leads to the activation of Gli2, which regulates the transcription of...
Schlagworte: N-[(4-chlorophenyl)methyl]-5,12-dioxo-2R-phenyl-1-oxa-4-azacyclododec-8E-ene-6S-acetamide
Anwendung: Shh inhibitor
CAS 1132653-79-2
MW: 455 D
520,00 €
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Zerumbone
Zerumbone

Artikelnummer: Cay15400-5

Zerumbone is a natural monocyclic sesquiterpene first isolated from rhizomes of the wild ginger Z. zerumbet. It potently inhibits the activation of Epstein-Barr virus by phorbol esters (IC50 = 140 nM). Zerumbone inhibits Sonic hedgehog signaling and induces apoptosis in cancer cell lines. It has also been shown to...
Schlagworte: (2E,6E)-2,6,9,9-tetramethyl-2,6,10E-cycloundecatrien-1-one
Anwendung: Sonic hedgehog signaling inhibitor, apoptosis inducer
CAS 471-05-6
MW: 218.3 D
ab 59,00 €
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