Zu "K11857" wurden 25 Artikel gefunden!
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P22077
Artikelnummer: Cay23704-5
P22077 is a dual inhibitor of the deubiquitylating enzymes ubiquitin-specific protease 7 (USP7) and USP47 (EC50s = 8.01 and 8.74 µM, respectively, in a fluorescence-based enzyme assay). It is selective for USP7 and USP47 over other USPs and proteases with EC50 values greater than 50 µM. P22077 (25 µM) induces the...
| Schlagworte: | 1-[5-[(2,4-difluorophenyl)thio]-4-nitro-2-thienyl]-ethanone |
| Anwendung: | USP7 / USP47 inhibitor |
| CAS | 1247819-59-5 |
| MW: | 315.3 D |
ab 69,00 €
Anti-USP47
Artikelnummer: A301-048A-T
Protein function: Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity. May also indirectly regulate CDC25A expression at a...
| Schlagworte: | Anti-USP47, EC=3.4.19.12, Anti-Ubiquitin thioesterase 47, Anti-Deubiquitinating enzyme 47, Anti-Ubiquitin... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
USP7-USP47 Inhibitor
Artikelnummer: Cay25622-1
USP7-USP47 inhibitor is a dual inhibitor of ubiquitin-specific protease 7 (USP7) and USP47 (IC50s = 0.42 and 1 µM, respectively). It is selective for USP7 and USP47 over USP2, USP5, USP8, USP21, USP28, caspase-3, and cathepsin B (IC50s = >31.6 µM). USP7-USP47 inhibitor inhibits the growth of HCT116 cells (EC50 = 7.6...
| Schlagworte: | 4-cyano-5-[(3,5-dichloro-4-pyridinyl)thio]-N-[4-(methylsulfonyl)phenyl]-2-thiophenecarboxamide |
| Anwendung: | USP7 inhibitor, USP47 inhibitor |
| CAS | 1247825-37-1 |
| MW: | 484.4 D |
ab 105,00 €
Anti-USP47
Artikelnummer: A301-049A
Protein function: Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity. May also indirectly regulate CDC25A expression at a...
| Schlagworte: | Anti-USP47, EC=3.4.19.12, Anti-Ubiquitin thioesterase 47, Anti-Deubiquitinating enzyme 47, Anti-Ubiquitin... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-USP47 (IHC)
Artikelnummer: IHC-00235
Protein function: Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity. May also indirectly regulate CDC25A expression at a...
| Schlagworte: | Anti-USP47, EC=3.4.19.12, Anti-Ubiquitin thioesterase 47, Anti-Deubiquitinating enzyme 47, Anti-Ubiquitin... |
| Anwendung: | IHC, IHC-IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Anti-USP47
Artikelnummer: ATA-HPA029286.100
Protein function: Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity. May also indirectly regulate CDC25A expression at a...
| Schlagworte: | Anti-USP47, EC=3.4.19.12, Anti-Ubiquitin thioesterase 47, Anti-Deubiquitinating enzyme 47, Anti-Ubiquitin... |
| Anwendung: | ICC, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 369,00 €
Anti-USP47
Artikelnummer: ATA-HPA029289.100
Protein function: Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity. May also indirectly regulate CDC25A expression at a...
| Schlagworte: | Anti-USP47, EC=3.4.19.12, Anti-Ubiquitin thioesterase 47, Anti-Deubiquitinating enzyme 47, Anti-Ubiquitin... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 246,00 €
Anti-USP47
Artikelnummer: CSB-PA045692.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: USP47. Antigen Species: Human
| Schlagworte: | Anti-USP47, EC=3.4.19.12, Anti-Ubiquitin thioesterase 47, Anti-Deubiquitinating enzyme 47, Anti-Ubiquitin... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 167,00 €
Anti-USP47
Artikelnummer: CSB-PA459673.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: USP47. Antigen Species: Human
| Schlagworte: | Anti-USP47, EC=3.4.19.12, Anti-Ubiquitin thioesterase 47, Anti-Deubiquitinating enzyme 47, Anti-Ubiquitin... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 167,00 €
Anti-USP47
Artikelnummer: E-AB-91163.120
Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB, stabilizing POLB thereby playing a role in base-excision repair (BER. Acts as a regulator of cell growth and genome integrity. May also indirectly regulate CDC25A expression at a transcriptional level. Protein...
| Schlagworte: | USP47, EC=3.4.19.12, Ubiquitin thioesterase 47, Deubiquitinating enzyme 47, Ubiquitin carboxyl-terminal hydrolase 47,... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 243,00 €
Anti-Usp47
Artikelnummer: CSB-PA636559XA01DLU.100
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Schlagworte: | Anti-Ubiquitin thioesterase 47, Anti-Ubiquitin carboxyl-terminal hydrolase 47, Anti-Ubiquitin-specific-processing protease... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | Drosophila melanogaster (Fruit fly) |
ab 1.529,00 €
USP47, Human ubiquitin specific peptidase 47, Real Time...
Artikelnummer: VHPS-9854
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | USP47, EC=3.4.19.12, Ubiquitin thiolesterase 47, Deubiquitinating enzyme 47, Ubiquitin carboxyl-terminal hydrolase 47,... |
| Anwendung: | RNA quantification |
45,00 €