Zu "K11839" wurden 29 Artikel gefunden!
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DUB-IN-3
Artikelnummer: Cay41594-10
DUB-IN-3 is an inhibitor of ubiquitin-specific protease 8 (USP8, IC50 = 0.56 µM). It is selective for USP8 over USP7 (IC50 = >100 µM). DUB-IN-3 is also an inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) papain-like protease (PLpro) when Z-LRGG-AMC is used as a substrate (IC50 = 12.5 µM) but...
| Schlagworte: | Deubiquitinase Inhibitor 3, Deubiquitinase-IN-3, DUBs Inhibitor 3, DUBs-IN-3, HBX 90397,... |
| Anwendung: | USB8 inhibitor |
| CAS | 924296-17-3 |
| MW: | 287.3 D |
ab 431,00 €
USP8-IN-1
Artikelnummer: Cay41598-1
USP8-IN-1 is an inhibitor of ubiquitin-specific protease 8 (USP8, IC50 = 2.6 µM). It is selective for USP8 over USP7 (IC50 = >20 µM). USP8-IN-1 inhibits colony formation by H1975 non-small cell lung cancer (NSCLC) cells (IC50 = 30.8 µM).Formal Name:...
| Schlagworte: | DC-U43-10, Ubiquitin-specific Protease 8 Inhibitor 1, USP8 Inhibitor 1,... |
| Anwendung: | USP8 inhibitor |
| CAS | 2477650-96-5 |
| MW: | 387.5 D |
ab 67,00 €
USP8-IN-2
Artikelnummer: Cay41599-1
USP8-IN-2 is an inhibitor of ubiquitin-specific protease 8 (USP8, IC50 = 6 µM).Formal Name: N-(5-chloro-2-methoxyphenyl)-N'-[1-[6-(trifluoromethyl)-2-pyridinyl]-4-piperidinyl]-thiourea. CAS Number: 2477651-11-7. Synonyms: Ubiquitin-specific Protease 8-IN-2, Ubiquitin-specific Protease 8 Inhibitor 2, USP Inhibitor 2....
| Schlagworte: | Ubiquitin-specific Protease 8 Inhibitor 2, Ubiquitin-specific Protease 8-IN-2, USP Inhibitor 2,... |
| Anwendung: | USP8 inhibitor |
| CAS | 2477651-11-7 |
| MW: | 444.9 D |
ab 73,00 €
USP8-IN-3
Artikelnummer: Cay41600-10
USP8-IN-3 is an inhibitor of ubiquitin-specific protease 8 (USP8, IC50 = 4 µM). It inhibits the growth of H1975 non-small cell lung cancer (NSCLC) and GH3 rat pituitary cells (GI50s = 6.01 and 37.03 µM).Formal Name: N-(4-nitrophenyl)-N'-[1-[6-(trifluoromethyl)-2-pyridinyl]-4-piperidinyl]-thiourea. CAS Number:...
| Schlagworte: | Ubiquitin-specific Protease 8 Inhibitor 3, Ubiquitin-specific Protease 8-IN-3, USP 8 Inhibitor 3,... |
| Anwendung: | USP8 inhibitor |
| CAS | 2477651-10-6 |
| MW: | 425.4 D |
ab 119,00 €
DUB-IN-1
Artikelnummer: Cay41737-10
DUB-IN-1 is an inhibitor of ubiquitin-specific protease 8 (USP8, IC50 = 0.85 µM). It is selective for USP8 over USP7 (IC50 = >100 µM). It inhibits the proliferation of LN-229, U87MG, and T98G glioblastoma cells when used at concentrations ranging from 200 to 800 nM. DUB-IN-1 (500 and 800 nM) reduces the migration...
| Schlagworte: | Deubiquitinase Inhibitor 1, Deubiquitinase-IN-1, DUB Inhibitor 1, DUBs Inhibitor 1, DUBs-IN-1, 9-[(phenylmethoxy)... |
| Anwendung: | USP8 inhibitor |
| CAS | 924296-18-4 |
| MW: | 337.3 D |
ab 132,00 €
Ubiquitin Isopeptidase Inhibitor I, G5
Artikelnummer: TGM-T17192-100mg
Description: Ubiquitin Isopeptidase Inhibitor I, G5 is a caspase-independent inducer of cell necrosis that induces cell death via the death receptor pathway (IC50 of 1.76 and 1.6 µM in E1A and E1A/C9DN cells, respectively). Target: Apoptosis. Smiles:...
| Schlagworte: | NSC144303 |
| Anwendung: | Ubiquitin Isopeptidase inhibitor |
| CAS | 108477-18-5 |
| MW: | 414.39 D |
ab 74,00 €
Anti-USP8
Artikelnummer: A302-929A
Protein function: Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell...
| Schlagworte: | Anti-USP8, Anti-hUBPy, Anti-KIAA0055, Anti-Ubiquitin thioesterase 8, Anti-Ubiquitin isopeptidase Y, Anti-Deubiquitinating... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 178,00 €
Anti-USP8
Artikelnummer: A302-930A-T
Protein function: Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell...
| Schlagworte: | Anti-USP8, Anti-hUBPy, Anti-KIAA0055, Anti-Ubiquitin thioesterase 8, Anti-Ubiquitin isopeptidase Y, Anti-Deubiquitinating... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 178,00 €
USP8 (UBPY), active human recombinant protein, N-terminal...
Artikelnummer: BPS-80358
Human USP8 (Ubiquitin-Specific Protease 8) or UBPY, GenBank Accession No. NM_005154, amino-acids 2-1118(end) with an N-terminal FLAG-tag, MW=128 kDa, expressed in a baculovirus-infected Sf9 cell expression system.
| Schlagworte: | hUBPy, KIAA0055, Ubiquitin isopeptidase Y, Ubiquitin thioesterase 8, Deubiquitinating enzyme 8, Ubiquitin... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | Baculovirus |
| Ursprungsart: | human |
| MW: | 128 kD |
640,00 €
Anti-USP8 / UBPY
Artikelnummer: ARG59799.100
Protein function: Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell...
| Schlagworte: | Anti-hUBPy, Anti-KIAA0055, Anti-Ubiquitin thioesterase 8, Anti-Ubiquitin isopeptidase Y, Anti-Deubiquitinating enzyme 8,... |
| Anwendung: | ICC, IF, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
658,00 €
Anti-USP8
Artikelnummer: ATA-HPA050215.100
Protein function: Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell...
| Schlagworte: | Anti-hUBPy, Anti-KIAA0055, Anti-Ubiquitin thioesterase 8, Anti-Ubiquitin isopeptidase Y, Anti-Deubiquitinating enzyme 8,... |
| Anwendung: | ICC, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 358,00 €
DUBs-IN-2
Artikelnummer: Cay36229-1
DUBs-IN-2 is an inhibitor of ubiquitin-specific protease 8 (USP8, IC50 = 280 nM). It is selective for USP8 over USP7 (IC50 = >100 µM). DUBs-IN-2 increases the level of programmed cell death protein ligand 1 (PD-L1) in H460 cells when used at a concentration of 2 µM and PC-9 cells at 2 and 4 µM. Intraperitoneal...
| Schlagworte: | Deubiquitinase Inhibitor 2, DUBs Inhibitor 2, HY-50737A, 9-(ethoxyimino)-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile |
| Anwendung: | USP8 inhibitor |
| CAS | 924296-19-5 |
| MW: | 275.3 D |
ab 83,00 €