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Anti-USP7
Artikelnummer: A300-033A
Protein function: Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX (PubMed:11923872, PubMed:15053880, PubMed:16964248, PubMed:18716620, PubMed:25283148). Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2...
| Schlagworte: | Anti-USP7, Anti-HAUSP, Anti-Ubiquitin thioesterase 7, Anti-Deubiquitinating enzyme 7, Anti-Ubiquitin carboxyl-terminal... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Anti-USP7/HAUSP Monoclonal Antibody
Artikelnummer: E-AN200056P.100
The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing...
| Schlagworte: | Ubiquitin thioesterase 7, Deubiquitinating enzyme 7, Ubiquitin carboxyl-terminal hydrolase 7,... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
389,00 €
Anti-USP7 (IHC)
Artikelnummer: IHC-00018
Protein function: Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX (PubMed:11923872, PubMed:15053880, PubMed:16964248, PubMed:18716620, PubMed:25283148). Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2...
| Schlagworte: | Anti-USP7, Anti-HAUSP, Anti-Ubiquitin thioesterase 7, Anti-Deubiquitinating enzyme 7, Anti-Ubiquitin carboxyl-terminal... |
| Anwendung: | IHC, IHC-IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Anti-USP7
Artikelnummer: A300-034A
Protein function: Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX (PubMed:11923872, PubMed:15053880, PubMed:16964248, PubMed:18716620, PubMed:25283148). Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2...
| Schlagworte: | Anti-USP7, Anti-HAUSP, Anti-Ubiquitin thioesterase 7, Anti-Deubiquitinating enzyme 7, Anti-Ubiquitin carboxyl-terminal... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
586,00 €
Anti-USP7
Artikelnummer: A303-943A
Protein function: Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX (PubMed:11923872, PubMed:15053880, PubMed:16964248, PubMed:18716620, PubMed:25283148). Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2...
| Schlagworte: | Anti-USP7, Anti-HAUSP, Anti-Ubiquitin thioesterase 7, Anti-Deubiquitinating enzyme 7, Anti-Ubiquitin carboxyl-terminal... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
HBX 41108
Artikelnummer: Cay23759-1
HBX 41108 is an uncompetitive, reversible inhibitor of ubiquitin-specific protease 7 (USP7) activity (IC50 = 424 nM). It dose-dependently inhibits USP7-mediated p53 deubiquitination in a cell-free assay, with an IC50 value of approximately 0.8 µM, as well as in HEK293 cells. It is selective for USP7 over a panel of...
| Schlagworte: | 7-chloro-9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile |
| Anwendung: | USP7 inhibitor |
| CAS | 924296-39-9 |
| MW: | 266.6 D |
ab 56,00 €
P005091
Artikelnummer: Cay15224-5
Ubiquitin-specific proteases (USP/UBP) remove ubiquitin from proteins, sparing them from degradation by the proteasome. USP7 is a cysteine protease associated with prostate cancer that selectively deubiquitylates HDM2, the ubiquitin E3 ligase for the tumor suppressor p53. P005091 is a trisubstituted thiophene that...
| Schlagworte: | P5091, 1-[5-[(2,3-dichlorophenyl)thio]-4-nitro-2-thienyl]-ethanone |
| Anwendung: | USP7 / USP47 inhibitor |
| CAS | 882257-11-6 |
| MW: | 348.2 D |
ab 99,00 €
USP7 Inhibitor Screening Assay Kit
Artikelnummer: BPS-79256
The USP7 Inhibitor Screening Assay Kit is designed to measure USP7 activity for screening and profiling applications. The USP7 Inhibitor Screening Assay Kit comes in a convenient format, with a 96-well plate, fluorogenic, ubiquitinated substrate, assay buffer, and purified USP7 enzyme for 96 enzyme reactions. USP7...
| Schlagworte: | Ubiquitin thioesterase 7, Deubiquitinating enzyme 7, Ubiquitin carboxyl-terminal hydrolase 7,... |
| Anwendung: | Enzyme kinetics, HTS |
| Spezies-Reaktivität: | human |
1.285,00 €
USP7, Active human recombinant protein
Artikelnummer: BPS-80395
Human ubiquitin specific peptidase 7 (USP7) or HAUSP, GenBank Accession No. NM_003470, a.a. 2 ? 1102 (end) with N-terminal His-Flag tag, MW = 130 kDa, expressed in an E. coli cell expression system.
| Schlagworte: | Ubiquitin thioesterase 7, Deubiquitinating enzyme 7, Ubiquitin carboxyl-terminal hydrolase 7,... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 130 kD |
640,00 €
Anti-HAUSP
Artikelnummer: 600-401-482
Protein function: Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal...
| Schlagworte: | Anti-USP7, Anti-HAUSP, EC=3.4.19.12, Anti-Ubiquitin thioesterase 7, Anti-Deubiquitinating enzyme 7, Anti-Ubiquitin... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
733,00 €
P005091
Artikelnummer: BPS-27767-1
P005091 is a selective, potent inhibitor of USP7 deubiquitylating activity.
| Schlagworte: | P005091, P5091, |
| Anwendung: | USP7 inhibitor |
| MW: | 348.2 D |
ab 314,00 €
NSC 632839
Artikelnummer: Cay16893-5
Protein ubiquitination is a dynamic process that can be reversed by deubiquitinating enzymes (DUBs) that remove ubiquitin from proteins, sparing them from degradation by the proteasome. The DUBs have been divided into various groups, the largest being the ubiquitin-specific proteases (USPs). NSC 632839 inhibits USP2...
| Schlagworte: | F6, Ubiquitin Isopeptidase Inhibitor II, 3,5-bis[(4-methylphenyl)methylene]-4-piperidinone, monohydrochloride |
| Anwendung: | USP2 / USP7 / SENP2 inhibitor |
| CAS | 157654-67-6 |
| MW: | 339.9 D |
ab 49,00 €