Zu "K11836" wurden 61 Artikel gefunden!
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Anti-USP5 / Ubiquitin specific peptidase 5, clone 32U18
Artikelnummer: NSJ-FY12506
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. USP5 antibody detects ubiquitin specific peptidase 5, a deubiquitinating enzyme encoded by the USP5 gene. USP5 is part of the ubiquitin specific protease family that cleaves ubiquitin from...
| Schlagworte: | Anti-USP5, Anti-Isopeptidase T, Anti-Ubiquitin thioesterase 5, Anti-Deubiquitinating enzyme 5, Anti-Ubiquitin... |
| Anwendung: | WB, ICC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-USP5 / Ubiquitin carboxyl-terminal hydrolase 5
Artikelnummer: NSJ-RQ8934
0.5mg/ml if reconstituted with 0.2ml sterile DI water. USP5 (Ubiquitin carboxyl-terminal hydrolase 5) is a member of the deubiquitinating enzyme (DUB) family, which plays a central role in regulating protein stability and turnover by processing ubiquitin chains. USP5 specifically disassembles unanchored...
| Schlagworte: | Anti-USP5, Anti-Isopeptidase T, Anti-Ubiquitin thioesterase 5, Anti-Deubiquitinating enzyme 5, Anti-Ubiquitin... |
| Anwendung: | WB, IHC (paraffin), IF, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-USP5
Artikelnummer: ATA-HPA006943.100
Rabbit Polyclonal USP5 Antibody against Human ubiquitin specific peptidase 5. Validated for Western Blot. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Interspecies information: Highest antigen sequence indentity to the following orthologs: ENSMUSG00000038429: 97%,...
| Schlagworte: | Anti-USP5, Anti-ISOT, EC=3.4.19.12, Anti-Isopeptidase T, Anti-Ubiquitin thioesterase 5, Anti-Deubiquitinating enzyme 5,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
491,00 €
Z-RLRGG-AMC (acetate)
Artikelnummer: Cay42457-1
Z-RLRGG-AMC is a fluorogenic substrate for isopeptidase T. Upon enzymatic cleavage by isopeptidase T, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify isopeptidase T activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.. Solulibility: DMSO:...
| Schlagworte: | Z-Arg-Leu-Arg-Gly-Gly-7-amino-4-methylcoumarin, Z-Arg-Leu-Arg-Gly-Gly-AMC,... |
| Anwendung: | Fluorogenic isopeptidase T (USP5) substrate |
| MW: | 848.95 D |
ab 58,00 €
Anti-USP5/IsoT
Artikelnummer: A301-542A
Protein function: Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys- 63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an...
| Schlagworte: | Anti-ISOT, Anti-USP5, EC=3.4.19.12, Anti-Isopeptidase T, Anti-Ubiquitin thioesterase 5, Anti-Deubiquitinating enzyme 5,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Spautin-1
Artikelnummer: Cay17769-10
Spautin-1 is an autophagy inhibitor, inducing cell death in human breast cancer Bcap-37 cells grown in glucose-free media (EC50 = ~1.25 µM). It does not significantly affect the viability of Bcap-37 cells grown in complete media. Spautin-1 promotes the degradation of Vps34 PI3K complex by inhibiting the...
| Schlagworte: | 6-fluoro-N-[(4-fluorophenyl)methyl]-4-quinazolinamine |
| Anwendung: | Autophagy inhibitor, USP10 / USP13 inhibitor |
| CAS | 1262888-28-7 |
| MW: | 271.3 D |
ab 49,00 €
Anti-USP5/IsoT
Artikelnummer: A301-543A
Protein function: Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys- 63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an...
| Schlagworte: | Anti-ISOT, Anti-USP5, EC=3.4.19.12, Anti-Isopeptidase T, Anti-Ubiquitin thioesterase 5, Anti-Deubiquitinating enzyme 5,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Z-LRGG-AMC (trifluoroacetate salt)
Artikelnummer: Cay26641-5
Z-LRGG-AMC is a fluorogenic substrate for isopeptidase T. Upon enzymatic cleavage by isopeptidase T, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify isopeptidase T activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.Formal Name:...
| Schlagworte: | Z-Leu-Arg-Gly-Gly-7-amino-4-methylcoumarin, Z-Leu-Arg-Gly-Gly-AMC,... |
| Anwendung: | Fluorogenic isopeptidase T substrate |
| MW: | 692.8 D |
ab 158,00 €
USP5 (IsoT), active human recombinant protein, N-terminal...
Artikelnummer: BPS-80355
Human USP5 (Ubiquitin-Specific Protease 5) or Isopeptidase T (IsoT), GenBank Accession No. NM_001098536, amino-acids 2-858(end) with an N-terminal FLAG-tag, MW=96 kDa, expressed in a baculovirus-infected Sf9 cell expression system.
| Schlagworte: | USP5, ISOT, EC=3.4.19.12, Isopeptidase T, Ubiquitin thioesterase 5, Deubiquitinating enzyme 5, Ubiquitin carboxyl-terminal... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | Baculovirus |
| Ursprungsart: | human |
| MW: | 96 kD |
640,00 €
Ubiquitin Isopeptidase Inhibitor I
Artikelnummer: Cay21006-10
Ubiquitin isopeptidase inhibitor I induces caspase activation and apoptosis (IC50 = ~1.7 µM) through a Bcl-2-dependent and apoptosome-independent mitochondrial pathway that selectively inhibits ubiquitin isopeptidase activity (IC50 = ~30 µM). It has also been shown to induce necrosis in apoptosis-resistant DKO...
| Schlagworte: | NSC 144303, tetrahydro-3,5-bis[(4-nitrophenyl)methylene]-4H-thiopyran-4-one, 1,1-dioxide |
| Anwendung: | Ubiquitin isopeptidase inhibitor |
| CAS | 108477-18-5 |
| MW: | 414.4 D |
ab 145,00 €
Anti-USP5/IsoT (IHC)
Artikelnummer: IHC-00313
Protein function: Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys- 63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an...
| Schlagworte: | Anti-ISOT, Anti-USP5, EC=3.4.19.12, Anti-Isopeptidase T, Anti-Ubiquitin thioesterase 5, Anti-Deubiquitinating enzyme 5,... |
| Anwendung: | IHC, IHC-IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-USP5
Artikelnummer: ARG59512.100
Protein function: Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys- 63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an...
| Schlagworte: | Anti-ISOT, Anti-USP5, EC=3.4.19.12, Anti-Isopeptidase T, Anti-Ubiquitin thioesterase 5, Anti-Deubiquitinating enzyme 5,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
707,00 €