Zu "K11757" wurden 29 Artikel gefunden!
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SMARCA-BD Ligand 1 for PROTAC (hydrochloride)
Artikelnummer: Cay45620-10
SMARCA-BD ligand 1 for PROTAC is a ligand for polybromo-1D (PBRM1), Brahma homolog (BRM), also known as SMARCA2, and Brahma-related gene 1 (BRG1), also known as SMARCA4 (Kds = 26, 135, and 73 nM, respectively). SMARCA-BD ligand 1 for PROTAC has been used in the synthesis of the proteolysis-targeting chimeras...
| Schlagworte: | SMARCA-BD Ligand 1 for Proteolysis-targeting Chimera, 2-[6-amino-5-(1-piperazinyl)-3-pyridazinyl]-phenol, dihydrochloride |
| Anwendung: | PBRM1 / BRM / BRG1 ligand |
| CAS | 2369053-68-7 |
| MW: | 344.2 D |
ab 244,00 €
Anti-PBRM1 / Polybromo 1
Artikelnummer: NSJ-FY13190
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. PBRM1 antibody detects Polybromo-1, a chromatin-remodeling factor and tumor suppressor that regulates gene expression through nucleosome repositioning. The UniProt recommended name is Polybromo-1 (PBRM1). This large nuclear protein functions...
| Schlagworte: | Anti-PBRM1, Anti-Polybromo-1D, Anti-Protein polybromo-1, Anti-BRG1-associated factor 180, PBRM1 Antibody / Polybromo 1 |
| Anwendung: | WB, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-PBRM1
Artikelnummer: A301-591A
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. [The UniProt Consortium]
| Schlagworte: | Anti-hPB1, Anti-PBRM1, Anti-BAF180, Anti-Polybromo-1D, Anti-Protein polybromo-1, Anti-BRG1-associated factor 180 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Anti-PBRM1
Artikelnummer: A301-590A
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. [The UniProt Consortium]
| Schlagworte: | Anti-hPB1, Anti-PBRM1, Anti-BAF180, Anti-Polybromo-1D, Anti-Protein polybromo-1, Anti-BRG1-associated factor 180 |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
ACBI1
Artikelnummer: TGM-T17350-1mg
Description: ACBI1 is a potent PROTAC degrader of BAF ATPase subunits SMARCA2 and SMARCA4, also degrades the polybromo-associated BAF (PBAF) complex member PBRM1, with DC50s of 6 nM, 11 nM and 32 nM for SMARCA2, SMARCA4 and PBRM1 in MV-4-11 cells, respectively. ACBI1 is composed of a bromodomain ligand, a linker,...
| Anwendung: | PROTAC (BRM/BRG1/PBRM1 degradation) |
| CAS | 2375564-55-7 |
| MW: | 936.1 D |
ab 93,00 €
-20 %
Rabattaktion
Anti-PBRM1 Recombinant Monoclonal
Artikelnummer: A700-019
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. [The UniProt Consortium]
| Schlagworte: | Anti-hPB1, Anti-PBRM1, Anti-BAF180, Anti-Polybromo-1D, Anti-Protein polybromo-1, Anti-BRG1-associated factor 180 |
| Anwendung: | WB, IP, IHC, ICC, IHC-IF, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
172,00 €
ab 137,60 €
PB1 (528-618), human recombinant protein, His-tag
Artikelnummer: BPS-31122
Human polybromo 1 (PB1), also known as PBRM1 and BRG1-associated factor 180, variant 2, (GenBank Accession No. NM_018313), amino-acids 528 ? 618 with N-terminal His-tag, MW = 11.7 kDa, expressed in an E. coli cell expression system.
| Schlagworte: | hPB1, PBRM1, BAF180, Polybromo-1D, Protein polybromo-1, BRG1-associated factor 180, |
| Anwendung: | BRD binding assays, inhibitor screening, selectivity profiling |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 11.7 kD |
461,00 €
PB1 (BD6), Human Recombinant Protein, His-tag
Artikelnummer: BPS-31133
Human polybromo 1 (PB1), also known as PBRM1 and BRG1-associated factor 180, variant 2, (GenBank Accession No. NM_018313), amino-acids 782-872 with N-terminal His-tag, MW = 12 kDa, expressed in an E. coli expression system.
| Schlagworte: | hPB1, PBRM1, BAF180, Polybromo-1D, Protein polybromo-1, BRG1-associated factor 180, |
| Anwendung: | Binding assays, screening inhibitors, selectivity profiling |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 12 kD |
461,00 €
Anti-PBRM1 / Baf180
Artikelnummer: ARG41551.100
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. [The UniProt Consortium]
| Schlagworte: | Anti-hPB1, Anti-PBRM1, Anti-BAF180, Anti-Polybromo-1D, Anti-Protein polybromo-1, Anti-BRG1-associated factor 180 |
| Anwendung: | FC, ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
658,00 €
Anti-PBRM1 / Baf180
Artikelnummer: ARG41585.100
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. [The UniProt Consortium]
| Schlagworte: | Anti-hPB1, Anti-PBRM1, Anti-BAF180, Anti-Polybromo-1D, Anti-Protein polybromo-1, Anti-BRG1-associated factor 180 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
707,00 €
Anti-PBRM1
Artikelnummer: ATA-HPA015629.100
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. [The UniProt...
| Schlagworte: | Anti-hPB1, Anti-PBRM1, Anti-BAF180, Anti-Polybromo-1D, Anti-Protein polybromo-1, Anti-BRG1-associated factor 180 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 369,00 €
Anti-PBRM1
Artikelnummer: ATA-HPA059373.100
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. [The UniProt...
| Schlagworte: | Anti-hPB1, Anti-PBRM1, Anti-BAF180, Anti-Polybromo-1D, Anti-Protein polybromo-1, Anti-BRG1-associated factor 180 |
| Anwendung: | WB, ICC, ChIP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 246,00 €