Zu "K11757" wurden 22 Artikel gefunden!
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Anti-PBRM1
Artikelnummer: A301-591A
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. [The UniProt Consortium]
| Schlagworte: | Anti-hPB1, Anti-PBRM1, Anti-BAF180, Anti-Polybromo-1D, Anti-Protein polybromo-1, Anti-BRG1-associated factor 180 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 164,00 €
SGC-SMARCA-BRDVIII
Artikelnummer: Cay33567-1
SGC-SMARCA-BRDVIII is a pan-inhibitor of family VIII bromodomain-containing proteins (BRDs), which are components of switch/sucrose nonfermentable (SWI/SNF) chromatin remodeling complexes. It selectively binds to polybromo-1D (PBRM1) bromodomain 5, BRM, also known as SMARCA2, and BRG1, also known as SMARCA4 (Kds =...
| Schlagworte: | 4-[3-amino-6-(2-hydroxyphenyl)-4-pyridazinyl]-1-piperazinecarboxylic acid, 1,1-dimethylethyl ester |
| Anwendung: | Pan-family VIII BRD inhibitor |
| CAS | 1997319-84-2 |
| MW: | 371.4 D |
ab 34,00 €
ACBI1
Artikelnummer: Cay36612-1
ACBI1 is a proteolysis-targeting chimera (PROTAC) composed of a ligand for BRM, also known as SMARCA2, BRG1, also known as SMARCA4, and polybromo-1D (PBRM1), which are components of switch/sucrose nonfermentable (SWI/SNF) chromatin remodeling complexes, conjugated to a von Hippel-Lindau (VHL) E3 ligase ligand. It...
| Schlagworte: | (2S,4R)-N-(2-(2-(4-((4-(3-amino-6-(2-hydroxyphenyl)pyridazin-4-yl)piperazin-1-yl)methyl)phenoxy)ethoxy)-4-(4-methylthiazol... |
| Anwendung: | PROTAC (BRM/BRG1/PBRM1 degradation) |
| CAS | 2375564-55-7 |
| MW: | 936.1 D |
ab 96,00 €
Anti-PBRM1
Artikelnummer: A301-590A
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. [The UniProt Consortium]
| Schlagworte: | Anti-hPB1, Anti-PBRM1, Anti-BAF180, Anti-Polybromo-1D, Anti-Protein polybromo-1, Anti-BRG1-associated factor 180 |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-PBRM1 Recombinant Monoclonal
Artikelnummer: A700-019
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. [The UniProt Consortium]
| Schlagworte: | Anti-hPB1, Anti-PBRM1, Anti-BAF180, Anti-Polybromo-1D, Anti-Protein polybromo-1, Anti-BRG1-associated factor 180 |
| Anwendung: | WB, IP, IHC, ICC, IHC-IF, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 172,00 €
PB1 (528-618), human recombinant protein, His-tag
Artikelnummer: BPS-31122
Human polybromo 1 (PB1), also known as PBRM1 and BRG1-associated factor 180, variant 2, (GenBank Accession No. NM_018313), amino-acids 528 ? 618 with N-terminal His-tag, MW = 11.7 kDa, expressed in an E. coli cell expression system.
| Schlagworte: | hPB1, PBRM1, BAF180, Polybromo-1D, Protein polybromo-1, BRG1-associated factor 180, |
| Anwendung: | BRD binding assays, inhibitor screening, selectivity profiling |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 11.7 kD |
452,00 €
PB1 (BD6), Human Recombinant Protein, His-tag
Artikelnummer: BPS-31133
Human polybromo 1 (PB1), also known as PBRM1 and BRG1-associated factor 180, variant 2, (GenBank Accession No. NM_018313), amino-acids 782-872 with N-terminal His-tag, MW = 12 kDa, expressed in an E. coli expression system.
| Schlagworte: | hPB1, PBRM1, BAF180, Polybromo-1D, Protein polybromo-1, BRG1-associated factor 180, |
| Anwendung: | Binding assays, screening inhibitors, selectivity profiling |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 12 kD |
452,00 €
Anti-PBRM1 / Baf180
Artikelnummer: ARG41551.100
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. [The UniProt Consortium]
| Schlagworte: | Anti-hPB1, Anti-PBRM1, Anti-BAF180, Anti-Polybromo-1D, Anti-Protein polybromo-1, Anti-BRG1-associated factor 180 |
| Anwendung: | FC, ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
624,00 €
Anti-PBRM1 / Baf180
Artikelnummer: ARG41585.100
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. [The UniProt Consortium]
| Schlagworte: | Anti-hPB1, Anti-PBRM1, Anti-BAF180, Anti-Polybromo-1D, Anti-Protein polybromo-1, Anti-BRG1-associated factor 180 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
624,00 €
Anti-PBRM1
Artikelnummer: G-CAB9878.100
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 352,00 €
Anti-PBRM1
Artikelnummer: ATA-HPA015629.100
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. [The UniProt...
| Schlagworte: | Anti-hPB1, Anti-PBRM1, Anti-BAF180, Anti-Polybromo-1D, Anti-Protein polybromo-1, Anti-BRG1-associated factor 180 |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 335,00 €
Anti-PBRM1
Artikelnummer: ATA-HPA059373.100
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. [The UniProt...
| Schlagworte: | Anti-hPB1, Anti-PBRM1, Anti-BAF180, Anti-Polybromo-1D, Anti-Protein polybromo-1, Anti-BRG1-associated factor 180 |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 335,00 €