Zu "K11724" wurden 25 Artikel gefunden!
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ABBV-744
Artikelnummer: TGM-T4697-100mg
Description: ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS. Target: Epigenetic Reader Domain, HIV Protease. Smiles: CCNC(=O)c1cc2c(cn(C)c(=O)c2[nH]1)-c1cc(ccc1Oc1c(C)cc(F)cc1C)C(C)(C)O. References: Emily J....
| Schlagworte: | ABBV744 |
| Anwendung: | BD2 bromodomain inhibitor |
| CAS | 2138861-99-9 |
| MW: | 491.55 D |
ab 39,00 €
BET bromodomain inhibitor 3
Artikelnummer: TGM-T79084-100mg
Description: BET Bromodomain Inhibitor 3 is a BET bromodomain inhibitor with an inhibitory Ki value of >40 µM against BrdT. It is utilized in research related to contraception, cancer, and heart disease [1]. Target: Epigenetic Reader Domain. Smiles: CN1C(=O)N(C)C2=C(C(C3=C(COC3=O)N2)C2=CC=C(C)C=C2)C1=O
| Anwendung: | BET bromodomain inhibitor |
| CAS | 854137-39-6 |
| MW: | 339.35 D |
ab 1.491,00 €
Anti-BRDT / Bromodomain testis-specific protein
Artikelnummer: NSJ-RQ7152
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Bromodomain testis-specific protein is a protein that in humans is encoded by the BRDT gene. BRDT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues),...
| Schlagworte: | Anti-CT9, Anti-BRDT, Anti-RING3-like protein, Anti-Cancer/testis antigen 9, Anti-Bromodomain testis-specific protein, BRDT... |
| Anwendung: | WB, FC, Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
755,00 €
MZ1
Artikelnummer: Cay21622-5
MZ1 is a hybrid compound that drives the selective proteasomal degradation of bromodomain-containing protein 4 (BRD4). It is characterized as a proteolysis-targeting chimera (PROTAC) and contains JQ-1, which binds bromo- and extra-terminal (BET) proteins, linked to a ligand for the E3 ubiquitin ligase VHL. MZ1...
| Schlagworte: | (4R)-N-[14-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]-1,13-dioxo-3... |
| Anwendung: | BRD4 degradation promotor |
| CAS | 1797406-69-9 |
| MW: | 1002.6 D |
ab 65,00 €
ABBV-744
Artikelnummer: Cay30470-10
ABBV-744 is an inhibitor of the bromodomain and extra-terminal domain (BET) family protein bromodomain 2 (BD2, Kis = 4.6, 4.9, 1.6, and 1 nM for BRD2, -3, -4, and -T, respectively). It is selective for BD2 over BD1 bromodomains in a time-resolved FRET (TR-FRET) assay (Kis = 1,162, 3,140, 521, and 917 nM for BRD2,...
| Schlagworte: | N-ethyl-4-[2-(4-fluoro-2,6-dimethylphenoxy)-5-(1-hydroxy-1-methylethyl)phenyl]-6,7-dihydro-6-methyl-7-oxo-1H-pyrrolo[2,3-c... |
| Anwendung: | BD2 bromodomain inhibitor |
| CAS | 2138861-99-9 |
| MW: | 491.6 D |
ab 92,00 €
BRDT (257-382), GST-tag, human recombinant protein
Artikelnummer: BPS-31060
Human Bromodomain testis-specific protein, also known as BRDT, BRD6, and CT9, amino-acids 257 ? 382 (GenBank Accession No. NM_207189) with N-terminal GST tag, MW = 41.7 kDa, expressed in an E. coli expression system.
| Schlagworte: | CT9, BRDT, RING3-like protein, Cancer/testis antigen 9, Bromodomain testis-specific protein, |
| Anwendung: | Binding assays, Inhibitor screening, Selectivity profiling |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 41.7 kD |
452,00 €
BRDT, BD1 and BD2 (22-382), GST-tag, human recombinant...
Artikelnummer: BPS-31061
Human Bromodomain testis-specific protein, also known as BRDT, BRD6, and CT9, amino-acids 22 ? 382 (GenBank Accession No. NM_207189) with N-terminal GST tag, MW = 68.1 kDa, expressed in an E. coli expression system.
| Schlagworte: | CT9, BRDT, RING3-like protein, Cancer/testis antigen 9, Bromodomain testis-specific protein, |
| Anwendung: | Binding assays, Inhibitor screening, Selectivity profiling |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 68.1 kD |
452,00 €
BRDT (257-382), His-tag, human recombinant protein
Artikelnummer: BPS-31100
Human Bromodomain testis-specific protein, also known as BRDT, BRD6, and CT9, amino-acids 257-382 (GenBank Accession No. NM_207189) with N-terminal HIS tag, MW = 15.8 kDa, expressed in an E. coli expression system.
| Schlagworte: | CT9, BRDT, RING3-like protein, Cancer/testis antigen 9, Bromodomain testis-specific protein, |
| Anwendung: | Binding assays, inhibitor screening, selectivity profiling |
| MW: | 15.8 kD |
452,00 €
BRDT (22-138), His-tag, human recombinant protein
Artikelnummer: BPS-31101
Human Bromodomain testis-specific protein, also known as BRDT, BRD6, and CT9, amino-acids 22-138 (GenBank Accession No. NM_207189) with N-terminal HIS tag, MW = 14.9 kDa, expressed in an E. coli expression system.
| Schlagworte: | CT9, BRDT, RING3-like protein, Cancer/testis antigen 9, Bromodomain testis-specific protein, |
| Anwendung: | Binding assays, inhibitor screening, selectivity profiling |
| MW: | 14.9 kD |
452,00 €
BRDT (22-138), GST-tag, human recombinant protein
Artikelnummer: BPS-31108
Human Bromodomain testis-specific protein, also known as BRDT, BRD6, and CT9, amino-acids 22 ? 138 (GenBank Accession No. NM_207189) with N-terminal GST tag, MW = 40.7 kDa, expressed in an E.coli expression system.
| Schlagworte: | CT9, BRDT, RING3-like protein, Cancer/testis antigen 9, Bromodomain testis-specific protein, |
| Anwendung: | Binding assays, inhibitor screening, selectivity profiling |
| MW: | 40.7 kD |
452,00 €
BRDT (BD1+BD2) TR-FRET Assay Kit
Artikelnummer: BPS-32616
Protein function: Testis-specific chromatin protein that specifically binds histone H4 acetylated at 'Lys-5' and 'Lys-8' (H4K5ac and H4K8ac, respectively) and plays a key role in spermatogenesis. Required in late pachytene spermatocytes: plays a role in meiotic and post-meiotic cells by binding to acetylated...
| Schlagworte: | Bromodomain testis-specific protein, BRDT, BRD6, CT9, |
| Anwendung: | Inhibitor screening, HTS |
| Spezies-Reaktivität: | human |
789,00 €
Anti-BRDT
Artikelnummer: NSJ-F40143-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. BRDT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues), characteristic of proteins that undergo rapid intracellular degradation. The bromodomain is found in...
| Schlagworte: | Anti-CT9, Anti-BRDT, Anti-RING3-like protein, Anti-Cancer/testis antigen 9, Anti-Bromodomain testis-specific protein, BRDT... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 326,00 €