Zu "K11722" wurden 119 Artikel gefunden!
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Anti-BRD4
Artikelnummer: A301-985A100
Protein function: Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation. Remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for...
| Schlagworte: | Anti-BRD4, Anti-HUNK1, Anti-Protein HUNK1, Anti-Bromodomain-containing protein 4 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
1.090,00 €
Anti-BRD4
Artikelnummer: A301-985A50
Protein function: Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation. Remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for...
| Schlagworte: | Anti-BRD4, Anti-HUNK1, Anti-Protein HUNK1, Anti-Bromodomain-containing protein 4 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
623,00 €
(+)-JQ1
Artikelnummer: Cay11187-5
The bromodomain and extra terminal domain (BET) family of proteins, including BRD2, BRD3, and BRD4, play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interaction by controlling the assembly of histone acetylation-dependent chromatin complexes. JQ1 displaces...
| Schlagworte: | (6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid,... |
| Anwendung: | BRD4 inhibitor |
| CAS | 1268524-70-4 |
| MW: | 457 D |
ab 35,00 €
Anti-BRD4 Recombinant Monoclonal
Artikelnummer: A700-005
Protein function: Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation. Remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for...
| Schlagworte: | Anti-BRD4, Anti-HUNK1, Anti-Protein HUNK1, Anti-Bromodomain-containing protein 4 |
| Anwendung: | WB, IP, IHC, IHC-IF, ICC-IF, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 172,00 €
RVX-297
Artikelnummer: Cay38777-10
RVX-297 is an inhibitor of the bromodomain and extra-terminal domain (BET) family protein bromodomain 2 (BD2). It inhibits BD2 in bromodomain-containing protein 2 (BRD2), BRD3, and BRD4, (IC50s = 0.08, 0.05, and 0.02 µM, respectively) and is selective for BD2 over BD1 (IC50s = 3.76, 2.34, and 1.16 µM for BRD2, BRD3,...
| Schlagworte: | 2-[3,5-dimethyl-4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-5,7-dimethoxy-4(3H)-quinazolinone |
| Anwendung: | BD2 bromodomain inhibitor |
| CAS | 1044871-04-6 |
| MW: | 423.5 D |
ab 101,00 €
Human BRD4 (Bromodomain Containing Protein 4) ELISA Kit
Artikelnummer: ELK-ELK5398.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human BRD4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human BRD4. Next,...
| Schlagworte: | BRD4, HUNK1, Protein HUNK1, Bromodomain-containing protein 4 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Anti-BRD4 Recombinant Monoclonal
Artikelnummer: A700-004
Protein function: Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation. Remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for...
| Schlagworte: | Anti-BRD4, Anti-HUNK1, Anti-Protein HUNK1, Anti-Bromodomain-containing protein 4 |
| Anwendung: | WB, IP, IHC, ICC, ICC-IF, ChIP-Seq, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 172,00 €
(+)-JQ1 Bromodomain Inhibitor
Artikelnummer: BPS-27400
(+)-JQ1 is a specific inhibitor of the BET family of acetyl-lysine recognition motifs, including the BRD2, BRD3, BRD4 and BRDT bromodomains. (+)-JQ1 has been shown to inhibit BRD4 (BD1) with a Kd of 50 nM, and BRD4 (BD2) with a Kd of 90 nM.
| Schlagworte: | BET inhibitor, Bromodomain inhibitor, |
| Anwendung: | BRD inhibitor |
| MW: | 456.99 D |
360,00 €
BRD4 (49-170), His-tag, human recombinant protein
Artikelnummer: BPS-31042
Human Bromodomain containing 4, also known as BRD4, HUNK1, or MCAP, amino-acids 49-170 (GenBank Accession No. NM_058243) with N-terminal His tag, MW = 15.5 kDa, expressed in an E. coli expression system.
| Schlagworte: | BRD4, HUNK1, Protein HUNK1, Bromodomain-containing protein 4, |
| Anwendung: | Binding assays, inhibitor screening, selectivity profiling |
| MW: | 15.5 kD |
452,00 €
BRD4 (342-460), His-tag, human recombinant protein
Artikelnummer: BPS-31043
Human Bromodomain containing 4, also known as BRD4, HUNK1, or MCAP, amino-acids 342-460 (GenBank Accession No. NM_058243) with N-terminal His tag, MW = 14.7 kDa, expressed in an E. coli expression system.
| Schlagworte: | BRD4, HUNK1, Protein HUNK1, Bromodomain-containing protein 4, |
| Anwendung: | Binding assays, inhibitor screening, selectivity profiling |
| MW: | 14.7 kD |
474,00 €
I-BET151
Artikelnummer: Cay11181-5
The bromodomain and extra terminal domain (BET) family of proteins including BRD2, BRD3, and BRD4 play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interaction by controlling the assembly of histone acetylation-dependent chromatin complexes. I-BET151 is an...
| Schlagworte: | GSK1210151A, 7,3,5-dimethyl-4-isoxazolyl-1,3-dihydro-8-methoxy-1-[1R-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one |
| Anwendung: | pan-BET family inhibitor |
| CAS | 1300031-49-5 |
| MW: | 415.5 D |
ab 48,00 €
CPI-203
Artikelnummer: Cay15479-1
(+)-JQ1 (Cay-11187) binds to the acetyl-lysine recognition pocket of bromodomains 1 and 2 on BRD4 with Kd values of ~50 and 90 nM, respectively. This displaces BRD4 from nuclear chromatin in cells, inducing differentiation and growth arrest in midline carcinoma cells. CPI-203 is a primary amide analog of (+)-JQ1...
| Schlagworte: | (6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide |
| Anwendung: | BRD4 binding inhibitor |
| CAS | 1446144-04-2 |
| MW: | 399.9 D |
ab 77,00 €