Zu "K11722" wurden 155 Artikel gefunden!
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Anti-BRD4
Artikelnummer: A301-985A100
Protein function: Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation. Remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for...
| Schlagworte: | Anti-BRD4, Anti-HUNK1, Anti-Protein HUNK1, Anti-Bromodomain-containing protein 4 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
1.169,00 €
Anti-BRD4
Artikelnummer: A301-985A50
Protein function: Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation. Remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for...
| Schlagworte: | Anti-BRD4, Anti-HUNK1, Anti-Protein HUNK1, Anti-Bromodomain-containing protein 4 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
668,00 €
(+)-JQ1
Artikelnummer: Cay11187-5
The bromodomain and extra terminal domain (BET) family of proteins, including BRD2, BRD3, and BRD4, play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interaction by controlling the assembly of histone acetylation-dependent chromatin complexes. JQ1 displaces...
| Schlagworte: | (6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid,... |
| Anwendung: | BRD4 inhibitor |
| CAS | 1268524-70-4 |
| MW: | 457 D |
ab 38,00 €
Bromodomain-containing protein 4 (BRD4), partial,...
Artikelnummer: CSB-YP002802HU3.1
Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 342-460aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: PAPEKSSKVS EQLKCCSGIL KEMFAKKHAA YAWPFYKPVD VEALGLHDYC DIIKHPMDMS TIKSKLEARE YRDAQEFGAD VRLMFSNCYK YNPPDHEVVA MARKLQDVFE MRFAKMPDE. Purity: Greater than...
| Schlagworte: | BRD4, HUNK1, Protein HUNK1, Bromodomain-containing protein 4 |
| Anwendung: | Activity not tested |
| Exprimiert in: | Yeast |
| Ursprungsart: | human |
| MW: | 15.8 kD |
ab 292,00 €
Anti-BRD4 Recombinant Monoclonal
Artikelnummer: A700-005
Protein function: Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation. Remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for...
| Schlagworte: | Anti-BRD4, Anti-HUNK1, Anti-Protein HUNK1, Anti-Bromodomain-containing protein 4 |
| Anwendung: | WB, IP, IHC, IHC-IF, ICC-IF, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 185,00 €
BRD4 degrader AT1
Artikelnummer: TGM-T5439-5mg
Description: BRD4 degrader AT1 is a highly selective Brd4 degrader based on PROTAC technology, with a Kd of 44 nM for Brd4BD2 in cells. Target: Epigenetic Reader Domain, PROTACs. Smiles:...
| Anwendung: | BRD4 degradation driving PROTAC |
| CAS | 2098836-45-2 |
| MW: | 972.68 D |
1.099,00 €
Dbet57
Artikelnummer: TGM-T5440-100mg
Description: dBET57 is heterobifunctional degrader of BRD4 based on the PROTAC technology, exhibits significant degradation of BRD4BD1 with a DC50/5h of 500 nM ,and inactive on BRD4BD2. Target: PROTACs, Epigenetic Reader Domain. Smiles:...
| Anwendung: | PROTAC, BRD4BD1 degradation |
| CAS | 1883863-52-2 |
| MW: | 699.18 D |
ab 42,00 €
A1874
Artikelnummer: TGM-T5442-100mg
Description: A1874 is a nutlin-based and BRD4-degrading PROTAC which induces BRD4 degradation in cells. Effective in inhibiting many cancer cell lines proliferation. Target: Epigenetic Reader Domain, PROTACs. Smiles: C(#N)[C@]1([C@H]([C@H](C(NC2=C(OC)C=C(C(NCCOCCOCCO...
| Anwendung: | BRD4 degradation driving PROTAC |
| CAS | 2064292-12-0 |
| MW: | 1173.59 D |
ab 228,00 €
JQ-1 (carboxylic acid)
Artikelnummer: TGM-T5443-100mg
Description: JQ-1 (carboxylic acid) is a cell-permeable BRD4 inhibitor with IC50s of 77 nM for BRD4(1) and 33 nM for BRD4(2). Target: Epigenetic Reader Domain. Smiles: CC=1C2=C(N3C([C@H](CC(O)=O)N=C2C4=CC=C(Cl)C=C4)=NN=C3C)SC1C. References: Rosner M , Hengstschl?Ger M . Targeting Epigenetic Readers in Cancer[J]. New...
| Schlagworte: | JQ-1 carboxylic acid |
| Anwendung: | BET family protein inhibitor |
| CAS | 202592-23-2 |
| MW: | 400.88 D |
ab 63,00 €
Bromosporine
Artikelnummer: TGM-T6255-100mg
Description: Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 µM), respectively. Target: CDK, Epigenetic Reader Domain. Smiles: CCOC(=O)Nc1cc(nn2c(C)nnc12)-c1ccc(C)c(NS(C)(=O)=O)c1. References: 15th HELLENIC SYMPOSIUM OF MEDICINAL CHEMISTRY.
| Anwendung: | Non-selective bromodomain inhibitor |
| CAS | 1619994-69-2 |
| MW: | 404.44 D |
ab 45,00 €
Bromodomain inhibitor-9
Artikelnummer: TGM-T63220-100mg
Description: Bromodomain inhibitor-9 is an inhibitor of Bromodomains that selectively inhibits the activity of BRD4-1 with a Kd value of 12 nM. Bromodomain inhibitor-9 can be used in studies of diseases related to systemic or lipid metabolism, tissue inflammation, fibrosis, or chronic autoimmune diseases. Target:...
| Anwendung: | Bromodomain inhibitor |
| CAS | 1870849-34-5 |
| MW: | 484.57 D |
ab 1.520,00 €
BRD4 Inhibitor-27
Artikelnummer: TGM-T78555-100mg
Description: BRD4 Inhibitor-27 is a potent BRD4 inhibitor that inhibits BRD4 BD1 and BRD4 BD2 with IC50s of 9.6 and 11.3 µM, respectively.BRD4 Inhibitor-27 has anticancer activity and can be used for breast cancer research. Target: Epigenetic Reader Domain. Smiles: FC(F)(F)C1=NN=C2C=CC(NCCC3=CNC4=C3C=CC=C4)=NN12....
| Anwendung: | BRD4 inhibitor |
| CAS | 930039-92-2 |
| MW: | 346.31 D |
ab 194,00 €