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SMARCA4 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-02217-10ug
Description: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a...
| Schlagworte: | ATP-dependent helicase SMARCA4 , SNF2B , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin... |
| MW: | 64.8 kD |
ab 81,00 €
SMARCA2 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-01905-10ug
Description: SMARCA2 Protein, Human, Recombinant (His) is expressed in Yeast.
| Schlagworte: | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 , Probable global... |
| MW: | 61.7 kD |
ab 81,00 €
Anti-Recombinant SMARCA2/BRM, clone A624
Artikelnummer: E-AN301908L.100
SMARCA2, also named as BRM, is a transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. SMARCA2 is involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D...
| Schlagworte: | Anti-SMARCA2, Anti-SNF2-alpha, Anti-Protein brahma homolog, Anti-BRG1-associated factor 190B, Anti-Probable global... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat, mouse |
ab 304,00 €
Anti-Zebrafish Smarca4a / Smarca4
Artikelnummer: NSJ-RZ1310
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Zebrafish Smarca4a is an ATP dependent chromatin remodeling enzyme that functions as the catalytic core of the Swi Snf type remodeling complexes. By using the energy of ATP hydrolysis, Smarca4a repositions or evicts nucleosomes to regulate access of...
| Schlagworte: | Anti-brg1, Anti-smarca4, Anti-smarca2, Anti-smarca4a, Anti-wu:fb51a08, Zebrafish Smarca4a Antibody / Smarca4 |
| Anwendung: | WB, IHC (paraffin), IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | zebrafish |
948,00 €
Anti-BRG1/SMARCA4 (IHC)
Artikelnummer: IHC-00466
Protein function: Transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an...
| Schlagworte: | Anti-SMARCA4, Anti-BAF190A, Anti-SNF2-beta, EC=3.6.4.-, Anti-Protein BRG-1, Anti-Protein brahma homolog 1,... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Anti-BRG1/SMARCA4
Artikelnummer: A300-813A
Protein function: Transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an...
| Schlagworte: | Anti-SMARCA4, Anti-BAF190A, Anti-SNF2-beta, EC=3.6.4.-, Anti-Protein BRG-1, Anti-Protein brahma homolog 1,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Anti-BRG1/SMARCA4
Artikelnummer: A303-877A
Protein function: Transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an...
| Schlagworte: | Anti-SMARCA4, Anti-BAF190A, Anti-SNF2-beta, EC=3.6.4.-, Anti-Protein BRG-1, Anti-Protein brahma homolog 1,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
AU-15330
Artikelnummer: Cay43318-1
A PROTAC that drives BRM and BRG1 degradation, induces degradation of BRM and BRG1 in HeLa cervical cancer cells at 1 µM but also induces degradation of PBRM1 at the same concentration, decreases proliferation in a panel of 14 cancer cell lines (IC50s = 0.392-28.85 nM), reduces protein levels of FOXA1, ERG, Myc, and...
| Schlagworte: | (2S,4R)-1-((S)-2-(2-(4-(3-amino-6-(2-hydroxyphenyl)pyridazin-4-yl)piperazin-1-yl)acetamido)-3,3-dimethylbutanoyl)-4-hydrox... |
| Anwendung: | BRM / BRG1 degradation driving PROTAC |
| CAS | 2380274-50-8 |
| MW: | 755.94 D |
ab 88,00 €
Anti-SMARCA2/BRM
Artikelnummer: A301-015A
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a...
| Schlagworte: | Anti-hBRM, Anti-BAF190B, EC=3.6.4.-, Anti-SNF2-alpha, Anti-Protein brahma homolog, Anti-BRG1-associated factor 190B,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
PFI-3
Artikelnummer: Cay15267-10
The SWI/SNF-related, Matrix-associated, Actin-dependent Regulator of Chromatin (SMARC) proteins integrate into complexes that remodel chromatin. The SMARC family A (SMARCA) members SMARCA2 (also known as BRM) and SMARCA4 (BRG1) are helicases that contain structurally-related bromodomains for binding acetylated...
| Schlagworte: | (2E)-1-(2-hydroxyphenyl)-3-[(1R,4R)-5-(2-pyridinyl)-2,5-diazabicyclo[2.2.1]hept-2-yl]-2-propen-1-one |
| Anwendung: | Bromodomain SMARCA4 / PB1 probe |
| CAS | 1819363-80-8 |
| MW: | 321.4 D |
ab 49,00 €
Anti-SMARCA2/BRM
Artikelnummer: A301-016A
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a...
| Schlagworte: | Anti-hBRM, Anti-BAF190B, EC=3.6.4.-, Anti-SNF2-alpha, Anti-Protein brahma homolog, Anti-BRG1-associated factor 190B,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
SMARCA2 (1375-1511), human recombinant protein,...
Artikelnummer: BPS-31111
Human Bromodomain SMARCA2 or BRM, amino-acids 1375 ? 1511 (GenBank Accession No. NM_003070) with N-terminal HIS-tag, MW = 16.9 kDa, expressed in an E. coli expression system.
| Schlagworte: | hBRM, BAF190B, SNF2-alpha, EC=3.6.4.-, Protein brahma homolog, BRG1-associated factor 190B, ATP-dependent helicase... |
| Anwendung: | BRD binding assays, inhibitor screening, selectivity profiling |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 16.9 kD |
461,00 €