Zu "K11547" wurden 35 Artikel gefunden!
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INH6
Artikelnummer: TGM-T6180-10mg
Description: INH6, an effective Hec1 inhibitor, selectively disrupts the Hec1/Nek2 interaction and induces chromosome mis-alignment. Target: Apoptosis, Microtubule Associated. Smiles: Cc1cc(C)c(-c2csc(NC(=O)c3ccccc3)n2)c(C)c1. References: Qiu XL, et al. J Med Chem. 2009, 52(6), 1757-1767.
| Anwendung: | NDC80 inhibitor |
| CAS | 1001753-24-7 |
| MW: | 322.42 D |
ab 42,00 €
Anti-NDC80
Artikelnummer: CSB-PA006498.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-HEC, Anti-NDC80, Anti-HsHec1, Anti-Kinetochore protein Hec1, Anti-Kinetochore-associated protein 2, Anti-Kinetochore... |
| Anwendung: | ELISA, WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
126,00 €
Anti-NDC80
Artikelnummer: CSB-PA215188.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-HEC, Anti-NDC80, Anti-HsHec1, Anti-Kinetochore protein Hec1, Anti-Kinetochore-associated protein 2, Anti-Kinetochore... |
| Anwendung: | ELISA, WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
283,00 €
INH1
Artikelnummer: Cay29015-5
INH1 is an inhibitor of the interaction between the oncogene high expression in cancer 1 (Hec1) and its regulator, the serine/threonine kinase Nek2. It binds to Hec1 and reduces Nek2 protein levels in HeLa cells when used at a concentration of 25 µM. INH1 inhibits the growth of MDA-MB-468, SK-BR-3, T47D, MDA-MB-361,...
| Schlagworte: | IBT 13131, N-[4-(2,4-dimethylphenyl)-2-thiazolyl]-benzamide |
| Anwendung: | Hec1 /Nek2 interaction inhibitor |
| CAS | 313553-47-8 |
| MW: | 308.4 D |
ab 78,00 €
Anti-HEC1
Artikelnummer: A300-771A
Protein function: Acts as a component of the essential kinetochore- associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:9315664, PubMed:12351790, PubMed:14654001, PubMed:14699129, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592,...
| Schlagworte: | Anti-HEC, Anti-NDC80, Anti-HsHec1, Anti-Kinetochore protein Hec1, Anti-Kinetochore-associated protein 2, Anti-Kinetochore... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 178,00 €
Anti-HEC1, C-terminal
Artikelnummer: ARG63469.100
Protein function: Acts as a component of the essential kinetochore- associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. [The UniProt...
| Schlagworte: | Anti-HEC, Anti-NDC80, Anti-HsHec1, Anti-Kinetochore protein Hec1, Anti-Kinetochore-associated protein 2, Anti-Kinetochore... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
822,00 €
Anti-HEC1
Artikelnummer: A300-770A
Protein function: Acts as a component of the essential kinetochore- associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:9315664, PubMed:12351790, PubMed:14654001, PubMed:14699129, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592,...
| Schlagworte: | Anti-HEC, Anti-NDC80, Anti-HsHec1, Anti-Kinetochore protein Hec1, Anti-Kinetochore-associated protein 2, Anti-Kinetochore... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 178,00 €
Anti-HEC1
Artikelnummer: NSJ-R36360-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Highly expressed in cancer, rich in leucine heptad repeats, NDC80 Protein function: Acts as a component of the essential kinetochore- associated NDC80 complex, which is required for chromosome...
| Schlagworte: | Anti-HEC, Anti-NDC80, Anti-HsHec1, Anti-Kinetochore protein Hec1, Anti-Kinetochore-associated protein 2, Anti-Kinetochore... |
| Anwendung: | WB, ELISA (peptide), IHC (paraffin) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
790,00 €
INH6
Artikelnummer: Cay21772-1
INH6 is an inhibitor of the oncogene high expression in cancer 1 (Hec1) and its regulator, the serine-threonine kinase Nek2, which together regulate mitotic spindle formation. It inhibits proliferation in human breast, cervical, and leukemia cell lines with IC50 values of 1.7 and 2.1, 2.4, and 2.5 µM, respectively,...
| Schlagworte: | N-[4-(2,4,6-trimethylphenyl)-2-thiazolyl]-benzamide |
| Anwendung: | NDC80 inhibitor |
| CAS | 1001753-24-7 |
| MW: | 322.4 D |
ab 47,00 €
Anti-HEC1 / NDC80, clone ACBI-14
Artikelnummer: NSJ-RQ4712
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding...
| Schlagworte: | Anti-HEC, Anti-NDC80, Anti-HsHec1, Anti-Kinetochore protein Hec1, Anti-Kinetochore-associated protein 2, Anti-Kinetochore... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
772,00 €
INH1
Artikelnummer: LKT-I530280.1
| Schlagworte: | Hec1/Nek2 Mitotic Pathway Inhibitor I, Benzamide,N-[4-(2,4-dimethylphenyl)-2-thiazolyl]-, IBT13131, AC1LIOIV,... |
| Anwendung: | Hec1/Nek2 interaction inhibitor, Apoptosis inducer |
| CAS | 313553-47-8 |
| MW: | 308.4 D |
ab 73,00 €
Anti-HEC1
Artikelnummer: ARG41383.100
Protein function: Acts as a component of the essential kinetochore- associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:9315664, PubMed:12351790, PubMed:14654001, PubMed:14699129, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592,...
| Schlagworte: | Anti-HEC, Anti-NDC80, Anti-HsHec1, Anti-Kinetochore protein Hec1, Anti-Kinetochore-associated protein 2, Anti-Kinetochore... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
658,00 €