Zu "K11454" wurden 28 Artikel gefunden!
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UNC3866
Artikelnummer: Cay19237-1
UNC3866 is an inhibitor of chromobox homolog 7 (CBX7, Kd = 97 nM). It also binds to CBX4 (Kd = 94 nM) but is greater than 6-fold selective over CBX2, 6, and 8 and the chromodomain Y family (CDY) chromodomains CDY1, L1b, and L2 (Kds = 0.61-6.3 µM). UNC3866 pretreatment (30 µM) of PC3 lysates completely inhibits...
| Schlagworte: | N-[4-(1,1-dimethylethyl)benzoyl]-L-phenylalanyl-L-alanyl-L-leucyl-N6,N6-diethyl-L-lysyl-L-serine, methyl ester |
| Anwendung: | CBX4 & CBX7 chromodomain antagonist |
| CAS | 1872382-47-2 |
| MW: | 795 D |
ab 74,00 €
MS37452
Artikelnummer: Cay17533-1
Chromobox homolog 7 (CBX7) functions through its N-terminal chromodomain, which recognizes histone 3 trimethyl lysine 27 (H3K27me3), to repress gene transcription. It plays a key role in gene transcription in cellular processes related to stem cell self-renewal and differentiation, as well as tumor progression....
| Schlagworte: | 1-[4-(2,3-dimethoxybenzoyl)-1-piperazinyl]-2-(3-methylphenoxy)-ethanone |
| Anwendung: | Competitive CBX7 chromodomain H3K27me3 binding inhibitor |
| CAS | 423748-02-1 |
| MW: | 398.5 D |
ab 59,00 €
Anti-CBX7
Artikelnummer: A302-525A
Protein function: Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates...
| Schlagworte: | Anti-CBX7, Anti-Chromobox protein homolog 7 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
CBX7, N-terminal His-tag, human recombinant protein
Artikelnummer: BPS-55017
Human chromobox homolog 7 (CBX7), GenBank Accession No. NM_175709, a.a. 2-90, with N-terminal His-tag, MW=11.6 kDa, expressed in an E. coli cell expression system.
| Schlagworte: | CBX7, Chromobox protein homolog 7, |
| Anwendung: | Binding assays, screening inhibitors, selectivity profiling |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 11.6 kD |
693,00 €
Anti-CBX7 (IHC)
Artikelnummer: IHC-00696
Protein function: Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates...
| Schlagworte: | Anti-CBX7, Anti-Chromobox protein homolog 7 |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-CBX7
Artikelnummer: E-AB-17698.120
CBX7 (Chromobox protein homolog 7) is a 251 amino acid nuclear protein that contains one N-terminal chromo domain and one C-terminal Pc box. Highly expressed in kidney, brain, heart and skeletal muscle, with weaker expression in peripheral blood leukocytes, CBX7 functions as a component of the chromatin-associated...
| Schlagworte: | Anti-CBX7, Anti-Chromobox protein homolog 7, CBX7 Polyclonal Antibody |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Anti-CBX7, clone ADHB-3
Artikelnummer: NSJ-RQ4819
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. Control of cell proliferation by Polycomb group proteins (PcG) is an important facet of cellular homeostasis and its disruption can promote tumorigenesis. 'Chromobox protein homolog 7' is a PcG protein which is found to control the growth of...
| Schlagworte: | Anti-CBX7, Anti-Chromobox protein homolog 7, CBX7 Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
790,00 €
Anti-CBX7
Artikelnummer: ATA-HPA048677.100
Protein function: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates...
| Schlagworte: | Anti-CBX7, Anti-Chromobox protein homolog 7 |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 246,00 €
Anti-CBX7
Artikelnummer: ATA-HPA056480.100
Protein function: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates...
| Schlagworte: | Anti-CBX7, Anti-Chromobox protein homolog 7 |
| Anwendung: | ICC, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 369,00 €
Chromobox protein homolog 7 (CBX7), human, recombinant
Artikelnummer: CSB-EP004603HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-251aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MELSAIGEQV FAVESIRKKR VRKGKVEYLV KWKGWPPKYS TWEPEEHILD PRLVMAYEEK EERDRASGYR KRGPKPKRLL LQRLYSMDLR SSHKAKGKEK LCFSLTCPLG SGSPEGVVKA GAPELVDKGP...
| Schlagworte: | CBX7, Chromobox protein homolog 7, Recombinant Human Chromobox protein homolog 7 (CBX7) |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 32.3 kD |
ab 219,00 €
Chromobox protein homolog 7 (CBX7), human, recombinant
Artikelnummer: CSB-YP004603HU.1
Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 1-251aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MELSAIGEQV FAVESIRKKR VRKGKVEYLV KWKGWPPKYS TWEPEEHILD PRLVMAYEEK EERDRASGYR KRGPKPKRLL LQRLYSMDLR SSHKAKGKEK LCFSLTCPLG SGSPEGVVKA GAPELVDKGP LVPTLPFPLR...
| Schlagworte: | CBX7, Chromobox protein homolog 7, Recombinant Human Chromobox protein homolog 7 (CBX7) |
| Anwendung: | Activity not tested |
| Exprimiert in: | Yeast |
| Ursprungsart: | human |
| MW: | 30.3 kD |
ab 242,00 €
Anti-CBX7
Artikelnummer: CSB-PA166159.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CBX7. Antigen Species: Human
| Schlagworte: | Anti-CBX7, Anti-Chromobox protein homolog 7, CBX7 antibody, Chromobox protein homolog 7 antibody, CBX7 Antibody |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €