Zu "K11439" wurden 16 Artikel gefunden!
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MS023 (hydrochloride)
Artikelnummer: Cay18361-1
MS023 is an inhibitor of type I protein arginine methyltransferases (PRMTs, IC50s = 30, 119, 83, 4, and 5 nM for PRMT1, -3, -4, -6, and -8, respectively). It is selective for these type I PRMTs over PRMT5, -7, and -9, as well as a panel of 25 protein lysine methyltransferases (PKMTs) and DNA methyltransferases...
| Schlagworte: | N1-methyl-N1-[[4-[4-(1-methylethoxy)phenyl]-1H-pyrrol-3-yl]methyl]-1,2-ethanediamine, trihydrochloride |
| Anwendung: | Potent, selective type I PRMT inhibitor |
| CAS | 2108631-19-0 |
| MW: | 396.8 D |
ab 85,00 €
PRMT8, active human recombinant protein
Artikelnummer: BPS-51052
Human PRMT8 (protein arginine methyltransferase 8), GenBank Accession No. NM_019854, amino acids 61-394(end) with N-terminal His-FLAG-tag, MW=40.8 kDa, expressed in Sf9 cells using a Baculovirus expression system.
| Schlagworte: | HRMT1L3, Protein arginine N-methyltransferase 8, Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | Baculovirus |
| Ursprungsart: | human |
| MW: | 40.8 kD |
678,00 €
MS023
Artikelnummer: Cay34786-5
MS023 is an inhibitor of type I protein arginine methyltransferases (PRMTs, IC50s = 30, 119, 83, 4, and 5 nM for PRMT1, -3, -4, -6, and -8, respectively). It is selective for these type I PRMTs over PRMT5, -7, and -9, as well as a panel of 25 protein lysine methyltransferases (PKMTs) and DNA methyltransferases...
| Schlagworte: | N1-methyl-N1-[[4-[4-(1-methylethoxy)phenyl]-1H-pyrrol-3-yl]methyl]-1,2-ethanediamine |
| Anwendung: | Type I PRMT inhibitor |
| CAS | 1831110-54-3 |
| MW: | 287.4 D |
ab 162,00 €
PRMT8 Homogeneous Assay Kit
Artikelnummer: BPS-52058
The PRMT8 Homogeneous Assay Kit is designed to measure the activity of PRMT8 for screening and profiling applications, using AlphaLISA (R) technology. The key to the PRMT8 Homogeneous Assay Kit is a highly specific antibody that recognizes methylated substrate. With this kit, only three simple steps on a microtiter...
| Schlagworte: | PRMT8, HRMT1L3, EC=2.1.1.-, Protein arginine N-methyltransferase 8, Heterogeneous nuclear ribonucleoprotein... |
| Anwendung: | Enzyme kinetics, small molecular inhibitor screening, drug discovery, HTS |
| Spezies-Reaktivität: | human |
1.715,00 €
Anti-PRMT8
Artikelnummer: NSJ-F41988-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Protein arginine methylation plays a role in signal transduction, RNA processing, transcriptional regulation, and DNA repair. PRMT8, a protein arginine N-methyltransferase most closely related to PRMT1, methylates the guanidino nitrogens of arginyl residues in some...
| Schlagworte: | Anti-PRMT8, Anti-HRMT1L3, EC=2.1.1.-, Anti-Protein arginine N-methyltransferase 8, Anti-Heterogeneous nuclear... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
PRMT8 Chemiluminescent Assay Kit
Artikelnummer: BPS-52062
The PRMT8 Chemiluminescent Assay Kit is designed to measure PRMT8 activity for screening and profiling applications. The key to the PRMT8 Chemiluminescent Assay Kit is a highly specific antibody that recognizes methylated R3 residue of Histone H4. With this kit, only three simple steps on a microtiter plate are...
| Schlagworte: | HRMT1L3, Protein arginine N-methyltransferase 8, Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4, |
| Anwendung: | Enzyme kinetics, HTS |
| Spezies-Reaktivität: | human |
1.182,00 €
Anti-PRMT8
Artikelnummer: NSJ-RQ5913
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Arginine methylation is a widespread posttranslational modification mediated by arginine methyltransferases, such as PRMT8. Arginine methylation is involved in a number of cellular processes, including DNA repair, RNA transcription, signal transduction, protein...
| Schlagworte: | Anti-HRMT1L3, Anti-Protein arginine N-methyltransferase 8, Anti-Heterogeneous nuclear ribonucleoprotein... |
| Anwendung: | WB, IHC (paraffin), Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
MS023 trihydrochloride
Artikelnummer: TGM-T77787-10mg
Description: MS023 trihydrochloride (MS023 3HCl) is a selective and potent human type I protein arginine methyltransferase (PRMT) inhibitor with potential anticancer activity against PRMT1, PRMT3, PRMT4, PRMT6, and PRMT8 for cancer research. Target: Histone Methyltransferase. Smiles:...
| Schlagworte: | MS023 3HCl |
| Anwendung: | Potent, selective type I PRMT inhibitor |
| CAS | 2108631-19-0 |
| MW: | 396.78 D |
ab 187,00 €
Anti-PRMT8
Artikelnummer: ARG45776.50
Protein function: S-adenosyl-L-methionine-dependent and membrane-associated arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA) in proteins such as NIFK, myelin basic protein, histone H4, H2A and H2A/H2B dimer (PubMed:16051612,...
| Schlagworte: | Anti-HRMT1L3, Anti-Protein arginine N-methyltransferase 8, Anti-Protein arginine N-methyltransferase 8, Anti-Heterogeneous... |
| Anwendung: | FC, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
501,00 €
Anti-prmt8b
Artikelnummer: CSB-PA735880XA01DIL.2
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Schlagworte: | Anti-zfL3, Anti-prmt8, Anti-prmt8b, Anti-Protein arginine N-methyltransferase 8-B, Anti-Heterogeneous nuclear... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | Danio rerio (Zebrafish) (Brachydanio rerio) |
ab 1.529,00 €
Anti-PRMT8, CT (Protein Arginine N-methyltransferase 8,...
Artikelnummer: P9004-36A.200
Protein arginine methylation plays a role in signal transduction, RNA processing, transcriptional regulation, and DNA repair. PRMT8, a protein arginine N-methyltransferase most closely related to PRMT1, methylates the guanidino nitrogens of arginyl residues in some proteins. This protein associates with the plasma...
| Schlagworte: | EC=2.1.1.-, Anti-Protein arginine N-methyltransferase 8, Anti-Heterogeneous nuclear ribonucleoprotein... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
865,00 €
PRMT8, Recombinant, Human, aa61-394, His-FLAG-Tag...
Artikelnummer: 377021.20
Membrane-associated arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA). Able to mono- and dimethylate EWS protein, however its precise role toward EWS remains unclear as it still interacts with fully methylated EWS. Source:...
| Schlagworte: | HRMT1L3, Protein arginine N-methyltransferase 8, Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4 |
| MW: | 40,8 |
1.152,00 €