Zu "K11437" wurden 35 Artikel gefunden!
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PRMT6, active human recombinant protein, N-terminal His-tag
Artikelnummer: BPS-51049
Human PRMT6 (GenBank Accession No. NM_018137), amino-acids 2-375(end), with N-terminal His-tag, MW=43 kDa, expressed in E. coli. Assay conditions: 50 µl reaction mix (20 mM phosphate buffer pH 7.4, 20 µM S-adenosylmethionine, and 1-5 ng methyl-transferase PRMT6) is added to microwells coated with histone substrate....
| Schlagworte: | PRMT6, HRMT1L6, Protein arginine N-methyltransferase 6, Histone-arginine N-methyltransferase PRMT6, Heterogeneous nuclear... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 43 kD |
488,00 €
Anti-PRMT6
Artikelnummer: A300-928A
Protein function: Arginine methyltransferase that can catalyze the formation of both omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA), with a strong preference for the formation of aDMA. Preferentially methylates arginyl residues present in a glycine and arginine-rich domain and displays...
| Schlagworte: | Anti-PRMT6, Anti-HRMT1L6, Anti-Protein arginine N-methyltransferase 6, Anti-Histone-arginine N-methyltransferase PRMT6,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-PRMT6
Artikelnummer: A300-929A
Protein function: Arginine methyltransferase that can catalyze the formation of both omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA), with a strong preference for the formation of aDMA. Preferentially methylates arginyl residues present in a glycine and arginine-rich domain and displays...
| Schlagworte: | Anti-PRMT6, Anti-HRMT1L6, Anti-Protein arginine N-methyltransferase 6, Anti-Histone-arginine N-methyltransferase PRMT6,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
GSK3368715 (hydrochloride)
Artikelnummer: Cay34886-1
GSK3368715 is an inhibitor of type I protein arginine methyltransferases (PRMTs, IC50s = 3.1, 162, 38, 4.7, and 39 nM for PRMT1, 3, 4, 6, and 8, respectively). It is selective for type I PRMTs over PRMT5, 7, and 9 (IC50s = >20,408, >40,000, and >15,000 nM, respectively), as well as 20 additional methyltransferases...
| Schlagworte: | N1-[[3-[4,4-bis(ethoxymethyl)cyclohexyl]-1H-pyrazol-4-yl]methyl]-N1,N2-dimethyl-1,2-ethanediamine, monohydrochloride |
| Anwendung: | Type I PRMT inhibitor |
| CAS | 2227587-25-7 |
| MW: | 403 D |
ab 104,00 €
EPZ020411
Artikelnummer: Cay19160-1
EPZ020411 is an inhibitor of protein arginine methyltranferase 6 (PRMT6, IC50 = 10 nM) that less potently targets PRMT1 and PRMT8 (IC50s = 119 and 223 nM, respectively). It dose-dependently decreases methylation of the PRMT6 substrate H3R2 in A375 cells transiently expressing PRMT6 (IC50 = 0.637 µM). EPZ020411 shows...
| Schlagworte: | N1,N2-dimethyl-N1-[[3-[4-[[trans-3-[2-(tetrahydro-2H-pyran-4-yl)ethoxy]cyclobutyl]oxy]phenyl]-1H-pyrazol-4-yl]methyl]-1,2-... |
| Anwendung: | Potent, selective PRMT6 inhibitor |
| CAS | 1700663-41-7 |
| MW: | 442.6 D |
ab 64,00 €
MS049 (hydrochloride)
Artikelnummer: Cay18348-1
MS049 is a potent and selective inhibitor of PRMT4 (IC50 = 34 nM) and PRMT6 (IC50 = 43 nM). It is less active against additional type I PRMTs (IC50s = >130, >220, and 1.6 µM for PRMT1, PRMT3, and PRMT8, respectively) and displays no inhibition against type II or type III PRMTs nor any additional methyltransferases...
| Schlagworte: | N-methyl-4-(phenylmethoxy)-1-piperidineethanamine, dihydrochloride |
| Anwendung: | PRMT4 inhibitor, PRMT6 inhibitor |
| CAS | 2095432-59-8 |
| MW: | 321.3 D |
ab 60,00 €
Anti-PRMT6, clone 2C3-F1-G1
Artikelnummer: ARG54004.100
Protein function: Arginine methyltransferase that can catalyze the formation of both omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA), with a strong preference for the formation of aDMA. Preferentially methylates arginyl residues present in a glycine and arginine-rich domain and displays...
| Schlagworte: | Anti-PRMT6, Anti-HRMT1L6, EC=2.1.1.-, EC=2.1.1.125, Anti-Protein arginine N-methyltransferase 6, Anti-Histone-arginine... |
| Anwendung: | WB, IHC (paraffin), ICC, IF |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
624,00 €
PRMT6 Chemiluminescent Direct Activity Assay Kit
Artikelnummer: BPS-52046
The PRMT6 Direct Activity Assay kit is designed to measure PRMT6 activity using purified PRMT6 or cell extracts containing PRMT6. The PRMT6 Direct Activity Assay Kit comes in a convenient format, with a 96-well plate precoated with histone H4 peptide substrate, the antibody against methylated arginine3 residue of...
| Schlagworte: | PRMT6, HRMT1L6, Protein arginine N-methyltransferase 6, Histone-arginine N-methyltransferase PRMT6, Heterogeneous nuclear... |
| Anwendung: | Enzyme kinetics, HTS |
1.101,00 €
PRMT6 Homogeneous Assay Kit
Artikelnummer: BPS-52056
The PRMT6 Homogeneous Assay Kit is designed to measure the activity of PRMT6 for screening and profiling applications, using AlphaLISA (R) technology. The key to the PRMT6 Homogeneous Assay Kit is a highly specific antibody that recognizes methylated substrate. With this kit, only three simple steps on a microtiter...
| Schlagworte: | PRMT6, HRMT1L6, |
| Anwendung: | Enzyme kinetics, small molecular inhibitor screening, drug discovery, HTS |
| Spezies-Reaktivität: | human |
2.134,00 €
PRMT6 (human recombinant, baculovirus expressed)
Artikelnummer: Cay13866-50
Protein arginine methyltransferases (PRMTs) are a family of enzymes with highly conserved catalytic domains that catalyze the transfer of a methyl group from S-adenosyl-L-methionine to a specific arginine residue in a target protein. PRMT6 is a nuclear type-1 PRMT, catalyzing the formation of...
| Schlagworte: | PRMT6, HRMT1L6, Protein arginine N-methyltransferase 6, Protein arginine N-methyltransferase 6, Histone-arginine... |
| Anwendung: | Enzyme activity |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
| MW: | 43,7 kD |
646,00 €
Anti-PRMT6
Artikelnummer: NSJ-R33955-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Protein arginine methyltransferase 6 Protein function: Arginine methyltransferase that can catalyze the formation of both omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine...
| Schlagworte: | Anti-PRMT6, Anti-HRMT1L6, Anti-Protein arginine N-methyltransferase 6, Anti-Histone-arginine N-methyltransferase PRMT6,... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
755,00 €
Anti-PRMT6 (IHC)
Artikelnummer: IHC-00488
Protein function: Arginine methyltransferase that can catalyze the formation of both omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA), with a strong preference for the formation of aDMA. Preferentially methylates arginyl residues present in a glycine and arginine-rich domain and displays...
| Schlagworte: | Anti-PRMT6, Anti-HRMT1L6, Anti-Protein arginine N-methyltransferase 6, Anti-Histone-arginine N-methyltransferase PRMT6,... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 164,00 €