Zu "K11434" wurden 58 Artikel gefunden!
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PRMT1 (human, recombinant)
Artikelnummer: Cay10350-50
Protein Arginine Methyltransferases (PRMTs) are S-adenosyl-L-methionine-dependent enzymes that catalyze post-translational modification of arginine residues by methylation in three different ways: monomethylation, symmetric dimethylation, or asymmetric dimethylation at terminal arginine guanidino nitrogen atoms....
| Schlagworte: | Interferon receptor 1-bound protein 4, Interferon receptor 1-bound protein 4, Protein arginine N-methyltransferase 1,... |
| Anwendung: | Enzyme activity |
| Exprimiert in: | E.coli |
| MW: | 69,2 kD |
489,00 €
PRMT1 (expressed Sf9), active human recombinant protein
Artikelnummer: BPS-51041
Active human PRMT1, GenBank Accession No. NM_001536, amino acids 2-end, with N-terminal GST tag, MW= 68 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
| Schlagworte: | Interferon receptor 1-bound protein 4, Protein arginine N-methyltransferase 1, Histone-arginine N-methyltransferase PRMT1, |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 68 kD |
498,00 €
PRMT1 (expressed E. coli), active human recombinant protein
Artikelnummer: BPS-51040
Active human PRMT1, GenBank Accession No. NM_001536, amino acids 2- end, with N-terminal GST tag, MW= 68 kDa, expressed in E. coli expression system.
| Schlagworte: | Interferon receptor 1-bound protein 4, Protein arginine N-methyltransferase 1, Histone-arginine N-methyltransferase PRMT1, |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 68 kD |
498,00 €
AMI-1
Artikelnummer: AG-CR1-0038-M005
Potent, cell permeable and specific protein arginine N-methyltransferase 1 (PRMT1) inhibitor (IC50 = 8, 8 µM), Does not compete for the AdoMet (S-adenosyl-L-methionine, SAM) binding site, Blocks peptide substrate binding, HIV-1 RT polymerase inhibitor (IC50 = 5, 0 µM).
| Schlagworte: | Arginine N-methyltransferase inhibitor-1 |
| Anwendung: | PRMT1 inhibitor |
| MW: | 592,4 D |
ab 39,00 €
AMI-1 (sodium salt)
Artikelnummer: Cay13965-5
AMI-1 is a cell permeable inhibitor of PRMTs. It inhibits both yeast Type I arginine methyltransferase Hmt1p and human PRMT1 (IC50 = 3.0 and 8.8 µM, respectively). AMI-1 also effectively blocks the activity of PRMTs 3, 4, and 6 but not that of either SET (Sub39H1, Suv39H2, SET7) or non-SET (DOT1) lysine...
| Schlagworte: | Arginine N-Methyltransferase Inhibitor-1, 7,7'-(carbonylbis(azanediyl))bis(4-oxidonaphthalene-2-sulfonate), sodium salt |
| Anwendung: | PRMTs Inhibitor |
| MW: | 592.4 D |
ab 139,00 €
MS023 (hydrochloride)
Artikelnummer: Cay18361-10
MS023 is an inhibitor of type I protein arginine methyltransferases (PRMTs, IC50s = 30, 119, 83, 4, and 5 nM for PRMT1, -3, -4, -6, and -8, respectively). It is selective for these type I PRMTs over PRMT5, -7, and -9, as well as a panel of 25 protein lysine methyltransferases (PKMTs) and DNA methyltransferases...
| Schlagworte: | N1-methyl-N1-[[4-[4-(1-methylethoxy)phenyl]-1H-pyrrol-3-yl]methyl]-1,2-ethanediamine, trihydrochloride |
| Anwendung: | Potent, selective type I PRMT inhibitor |
| CAS | 2108631-19-0 |
| MW: | 396.8 D |
ab 85,00 €
Anti-PRMT1, clone 4E9-H9-H12
Artikelnummer: ARG54089.100
Protein function: Arginine methyltransferase that methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in proteins such as ESR1, histone H2, H3 and H4, PIAS1, HNRNPA1, HNRNPD, NFATC2IP, SUPT5H, TAF15 and EWS. Constitutes the main enzyme that mediates monomethylation and...
| Schlagworte: | Anti-HMT2, Anti-PRMT1, EC=2.1.1.-, EC=2.1.1.125, Anti-Interferon receptor 1-bound protein 4, Anti-Protein arginine... |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
658,00 €
Anti-PRMT1
Artikelnummer: A300-722A
Protein function: Arginine methyltransferase that methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in proteins such as ESR1, histone H2, H3 and H4, PIAS1, HNRNPA1, HNRNPD, NFATC2IP, SUPT5H, TAF15, EWS, HABP4 and SERBP1 (PubMed:16879614). Constitutes the main enzyme...
| Schlagworte: | Anti-Interferon receptor 1-bound protein 4, Anti-Protein arginine N-methyltransferase 1, Anti-Histone-arginine... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
PRMT1 Homogeneous Assay Kit
Artikelnummer: BPS-52054
The PRMT1 Homogeneous Assay Kit is designed to measure activity of PRMT1 in purified enzyme complex or in cell extracts containing PRMT1, using AlphaScreen or AlphaLISA technology. PRMT1 is a histone methyltransferase that exhibits methylation activity toward H4-R3. The PRMT1 Homogeneous Assay Kit comes in a...
| Schlagworte: | PRMT1, HRMT1L2, IR1B4, HCP1, |
| Anwendung: | Enzyme kinetics, HTS |
1.795,00 €
Anti-PRMT1
Artikelnummer: NSJ-F40434-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory...
| Schlagworte: | Anti-HMT2, Anti-PRMT1, Anti-Interferon receptor 1-bound protein 4, Anti-Protein arginine N-methyltransferase 1,... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-PRMT1
Artikelnummer: NSJ-F40435-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory...
| Schlagworte: | Anti-HMT2, Anti-PRMT1, Anti-Interferon receptor 1-bound protein 4, Anti-Protein arginine N-methyltransferase 1,... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 361,00 €
TC-E 5003
Artikelnummer: Cay17718-100
TC-E 5003 is an inhibitor of protein arginine methyltransferase 1 (PRMT1, IC50 = 1.5 µM for human PRMT1 in a methylation assay). It is selective for PRMT1 over PRMT4/CARM1 and SET7/9 methyltransferases, with less than 5% inhibition at a concentration of 50 µM for SET7/9. TC-E 5003 inhibits growth of MCF-7a breast...
| Schlagworte: | NSC 30176, N,N'-(sulfonyldi-4,1-phenylene)bis[2-chloro]-acetamide |
| CAS | 17328-16-4 |
| MW: | 401.3 D |
ab 67,00 €