Zu "K11429" wurden 48 Artikel gefunden!
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A-196
Artikelnummer: Cay18317-1
A-196 is a selective inhibitor of SUV420H1 and SUV420H2 (IC50s = 25 and 144 nM, respectively) that is more than 100-fold selective over other histone methyltransferases and non-epigenetic targets. A-196 has been shown to inhibit the di- and tri-methylation of lysine 20 of histone H4 (H4K20me) in multiple cell lines...
| Schlagworte: | 6,7-dichloro-N-cyclopentyl-4-(4-pyridinyl)-1-phthalazinamine |
| Anwendung: | SUV420H1 & SUV420H2 inhibitor |
| CAS | 1982372-88-2 |
| MW: | 359.3 D |
ab 38,00 €
SUV4-20h2, active human recombinant protein
Artikelnummer: BPS-51060
Active human SUV4-20h2 (GenBank Accession No. NM_032701), amino acids 2-280, with N-terminal GST tag, MW= 58 kDa, expressed in E. coli expression system.
| Schlagworte: | PP7130, SUV420H2, Suv4-20h2, Su(var)4-20 homolog 2, Lysine N-methyltransferase 5C, Lysine-specific methyltransferase 5C,... |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 58 kD |
663,00 €
SUV4-20h1, active human recombinant protein
Artikelnummer: BPS-51090
Active human SUV4-20H1 (GenBank Accession No. NM_017635), amino acids 2-387, with N-terminal GST tag, MW= 70 kDa, expressed in E. coli expression system.
| Schlagworte: | CGI-85, SUV420H1, Suv4-20h1, Su(var)4-20 homolog 1, Lysine N-methyltransferase 5B, Lysine-specific methyltransferase 5B,... |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 70 kD |
663,00 €
SUV4-20H1 Chemiluminescent Assay kit
Artikelnummer: BPS-53011
The SUV4-20H1 Chemiluminescent Assay Kit is designed to measure SUV4-20H1 activity for screening and profiling applications. The SUV4-20H1 Chemiluminescent Assay Kit comes in a convenient format, with 96-well plate precoated with histone H4 substrate, an antibody against methylated lysine residue of Histone H4,...
| Schlagworte: | Suppressor Of Variegation 4-20 Homolog 1 , KMT5B, SUV420H1, |
| Anwendung: | Enzyme kinetics, HTS |
| Spezies-Reaktivität: | human |
1.182,00 €
Anti-KMT5C
Artikelnummer: ATA-HPA052294.100
Protein function: Histone methyltransferase that specifically methylates monomethylated 'Lys-20' (H4K20me1) and dimethylated 'Lys-20' (H4K20me2) of histone H4 to produce respectively dimethylated 'Lys-20' (H4K20me2) and trimethylated 'Lys-20' (H4K20me3) and thus regulates transcription and maintenance of genome...
| Schlagworte: | Anti-PP7130, Anti-SUV420H2, Anti-Suv4-20h2, Anti-Su(var)4-20 homolog 2, Anti-Lysine N-methyltransferase 5C,... |
| Anwendung: | ICC, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 246,00 €
Anti-KMT5B
Artikelnummer: ATA-HPA063648.100
Protein function: Histone methyltransferase that specifically methylates monomethylated 'Lys-20' (H4K20me1) and dimethylated 'Lys-20' (H4K20me2) of histone H4 to produce respectively dimethylated 'Lys-20' (H4K20me2) and trimethylated 'Lys-20' (H4K20me3) and thus regulates transcription and maintenance of genome...
| Schlagworte: | Anti-CGI-85, Anti-SUV420H1, Anti-Suv4-20h1, Anti-Su(var)4-20 homolog 1, Anti-Lysine N-methyltransferase 5B,... |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 246,00 €
A-196
Artikelnummer: TGM-T4343-100mg
Description: A-196 is a potent and selective inhibitor of SUV420h1 and SUV420h2, with IC50 values of 0.025 µM and 0.144 µM, respectively, it is more than 100-fold selective over other histone methyltransferases and non-epigenetic targets. Target: Histone Methyltransferase. Smiles:...
| Schlagworte: | A 196 |
| Anwendung: | SUV420H1 & SUV420H2 inhibitor |
| CAS | 1982372-88-2 |
| MW: | 359.25 D |
ab 34,00 €
SUV420H2 Protein, Human, Recombinant (His & GST)
Artikelnummer: TGM-TMPY-01657-50ug
Description: Histone-lysine N-methyltransferase SUV42H2, also known as Suppressor of variegation 4-2 homolog 2, Su(var)4-2 homolog 2, Lysine N-methyltransferase 5C, SUV42H2 and KMT5C, is nucleus protein that belongs to the histone-lysine methyltransferase family and Suvar4-2 subfamily. SUV42H2 is a histone...
| Schlagworte: | KMT5C, suppressor of variegation 4-20 homolog 2 (Drosophila) |
| MW: | 60 kD |
658,00 €
Anti-KMT5C
Artikelnummer: ATA-HPA075095.100
Polyclonal Antibody against Human KMT5C, Gene description: lysine methyltransferase 5C, Alternative Gene Names: MGC2705, SUV420H2, Validated applications: ICC, Uniprot ID: Q86Y97, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein function: Histone methyltransferase...
| Schlagworte: | Anti-PP7130, Anti-SUV420H2, Anti-Suv4-20h2, Anti-Su(var)4-20 homolog 2, Anti-Lysine N-methyltransferase 5C,... |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
491,00 €
NEU
SUV420H2 Protein, Human, Recombinant (His & GST)
Artikelnummer: TGM-TMPY-01657-10ug
Description: Histone-lysine N-methyltransferase SUV42H2, also known as Suppressor of variegation 4-2 homolog 2, Su(var)4-2 homolog 2, Lysine N-methyltransferase 5C, SUV42H2 and KMT5C, is nucleus protein that belongs to the histone-lysine methyltransferase family and Suvar4-2 subfamily. SUV42H2 is a histone...
| Schlagworte: | suppressor of variegation 4-20 homolog 2 (Drosophila) , KMT5C |
| MW: | 60 kD |
ab 102,00 €
Anti-KMT5C / SUV420H2
Artikelnummer: NSJ-F55096-0.05ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. KMT5C, also called Suppressor of variegation 4-20 homolog 2, Su(var)4-20 homolog 2 and Suv4-20h2, belongs to a family of proteins called lysine methyltransferases, which are enzymes that play a key role in the modification of histone proteins. Histones are proteins that...
| Schlagworte: | Anti-PP7130, Anti-SUV420H2, Anti-Suv4-20h2, Anti-Su(var)4-20 homolog 2, Anti-Lysine N-methyltransferase 5C,... |
| Anwendung: | WB, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 361,00 €
KMT5B (human), recombinant protein
Artikelnummer: ABS-PP-10326-L.100
Protein function: Histone methyltransferase that specifically methylates monomethylated 'Lys-20' (H4K20me1) and dimethylated 'Lys-20' (H4K20me2) of histone H4 to produce respectively dimethylated 'Lys-20' (H4K20me2) and trimethylated 'Lys-20' (H4K20me3) and thus regulates transcription and maintenance of genome...
| Schlagworte: | Histone-lysine N-methyltransferase KMT5B, Lysine N-methyltransferase 5B, Lysine-specific methyltransferase 5B, Suppressor... |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 15 kD |
ab 115,00 €