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A-196
A-196

Artikelnummer: Cay18317-1

A-196 is a selective inhibitor of SUV420H1 and SUV420H2 (IC50s = 25 and 144 nM, respectively) that is more than 100-fold selective over other histone methyltransferases and non-epigenetic targets. A-196 has been shown to inhibit the di- and tri-methylation of lysine 20 of histone H4 (H4K20me) in multiple cell lines...
Schlagworte: 6,7-dichloro-N-cyclopentyl-4-(4-pyridinyl)-1-phthalazinamine
Anwendung: SUV420H1 & SUV420H2 inhibitor
CAS 1982372-88-2
MW: 359.3 D
ab 43,00 €
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SUV4-20h2, active human recombinant protein
SUV4-20h2, active human recombinant protein

Artikelnummer: BPS-51060

Active human SUV4-20h2 (GenBank Accession No. NM_032701), amino acids 2-280, with N-terminal GST tag, MW= 58 kDa, expressed in E. coli expression system.
Schlagworte: PP7130, SUV420H2, Suv4-20h2, Su(var)4-20 homolog 2, Lysine N-methyltransferase 5C, Lysine-specific methyltransferase 5C,...
Anwendung: Enzyme kinetics, inhibitor screening
MW: 58 kD
650,00 €
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SUV4-20h1, active human recombinant protein
SUV4-20h1, active human recombinant protein

Artikelnummer: BPS-51090

Active human SUV4-20H1 (GenBank Accession No. NM_017635), amino acids 2-387, with N-terminal GST tag, MW= 70 kDa, expressed in E. coli expression system.
Schlagworte: CGI-85, SUV420H1, Suv4-20h1, Su(var)4-20 homolog 1, Lysine N-methyltransferase 5B, Lysine-specific methyltransferase 5B,...
Anwendung: Enzyme kinetics, inhibitor screening
MW: 70 kD
650,00 €
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SUV4-20H1 Chemiluminescent Assay kit
SUV4-20H1 Chemiluminescent Assay kit

Artikelnummer: BPS-53011

The SUV4-20H1 Chemiluminescent Assay Kit is designed to measure SUV4-20H1 activity for screening and profiling applications. The SUV4-20H1 Chemiluminescent Assay Kit comes in a convenient format, with 96-well plate precoated with histone H4 substrate, an antibody against methylated lysine residue of Histone H4,...
Schlagworte: Suppressor Of Variegation 4-20 Homolog 1 , KMT5B, SUV420H1,
Anwendung: Enzyme kinetics, HTS
Spezies-Reaktivität: human
1.101,00 €
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Anti-SUV420H1
Anti-SUV420H1

Artikelnummer: G-CAB15442.100

WB 1:200 - 1:2000. Protein function: Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the...
Schlagworte: Anti-CGI-85, Anti-SUV420H1, Anti-Suv4-20h1, EC=2.1.1.43, Anti-Su(var)4-20 homolog 1, Anti-Lysine N-methyltransferase 5B,...
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 352,00 €
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Anti-KMT5C
Anti-KMT5C

Artikelnummer: G-CAB16235.100

WB 1:500 - 1:2000. Protein function: Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the...
Schlagworte: Anti-PP7130, Anti-SUV420H2, Anti-Suv4-20h2, EC=2.1.1.43, Anti-Su(var)4-20 homolog 2, Anti-Lysine N-methyltransferase 5C,...
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 352,00 €
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Anti-KMT5C
Anti-KMT5C

Artikelnummer: ATA-HPA052294.100

Protein function: Histone methyltransferase that specifically methylates monomethylated 'Lys-20' (H4K20me1) and dimethylated 'Lys-20' (H4K20me2) of histone H4 to produce respectively dimethylated 'Lys-20' (H4K20me2) and trimethylated 'Lys-20' (H4K20me3) and thus regulates transcription and maintenance of genome...
Schlagworte: Anti-PP7130, Anti-SUV420H2, Anti-Suv4-20h2, Anti-Su(var)4-20 homolog 2, Anti-Lysine N-methyltransferase 5C,...
Anwendung: ICC, IHC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 335,00 €
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Anti-KMT5B
Anti-KMT5B

Artikelnummer: ATA-HPA063648.100

Protein function: Histone methyltransferase that specifically methylates monomethylated 'Lys-20' (H4K20me1) and dimethylated 'Lys-20' (H4K20me2) of histone H4 to produce respectively dimethylated 'Lys-20' (H4K20me2) and trimethylated 'Lys-20' (H4K20me3) and thus regulates transcription and maintenance of genome...
Schlagworte: Anti-CGI-85, Anti-SUV420H1, Anti-Suv4-20h1, Anti-Su(var)4-20 homolog 1, Anti-Lysine N-methyltransferase 5B,...
Anwendung: ICC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 335,00 €
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Anti-KMT5C (KO Validated)
Anti-KMT5C (KO Validated)

Artikelnummer: E-AB-93148.120

SUV420H2 and the related enzyme SUV420H1 (MIM 610881) function as histone methyltransferases that specifically trimethylate nucleosomal histone H4 (see MIM 602822) on lysine-20 (K20). Protein function: Histone methyltransferase that specifically methylates monomethylated 'Lys-20' (H4K20me1) and dimethylated 'Lys-20'...
Schlagworte: PP7130, SUV420H2, Suv4-20h2, Su(var)4-20 homolog 2, Lysine N-methyltransferase 5C, Lysine-specific methyltransferase 5C,...
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 218,00 €
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CGI-85, Human, Real Time PCR Primer Set
CGI-85, Human, Real Time PCR Primer Set

Artikelnummer: VHPS-1883

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Schlagworte: KMT5B, SUV420H1, Suv4-20h1, EC=2.1.1.43, Su(var)4-20 homolog 1, Lysine N-methyltransferase 5B, Suppressor of variegation...
Anwendung: RNA quantification
43,00 €
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SUV420H1, Human suppressor of variegation 4-20 homolog 1 (Drosophila), Real Time PCR Primer Set
SUV420H1, Human suppressor of variegation 4-20 homolog 1...

Artikelnummer: VHPS-9003

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Schlagworte: KMT5B, SUV420H1, Suv4-20h1, EC=2.1.1.43, Su(var)4-20 homolog 1, Lysine N-methyltransferase 5B, Suppressor of variegation...
Anwendung: RNA quantification
43,00 €
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Suv420H1, Mouse suppressor of variegation 4-20 homolog 1 (Drosophila), Real Time PCR Primer Set
Suv420H1, Mouse suppressor of variegation 4-20 homolog 1...

Artikelnummer: VMPS-6399

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Schlagworte: Suv420h1, Suv4-20h1, EC=2.1.1.43, Su(var)4-20 homolog 1, Suppressor of variegation 4-20 homolog 1, Histone-lysine...
Anwendung: RNA quantification
43,00 €
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