Zu "K11428" wurden 39 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
Ryuvidine
Artikelnummer: Cay16614-5
SET domain-containing protein 8 (SETD8) is a methyltransferase that selectively monomethylates histone H4 at lysine residue 20 (H4K20), an event proven to have an important role in chromatin structure and transcriptional activation. It is also a regulator of p53, mono-methylating lysine 382 of the tumor suppressor....
| Schlagworte: | Cdk4 Inhibitor III, Cyclic-dependent Kinase 4 Inhibitor III, SPS812,... |
| Anwendung: | SETD8 inhibitor |
| CAS | 265312-55-8 |
| MW: | 284.3 D |
ab 50,00 €
UNC0379
Artikelnummer: Cay16400-5
SET domain-containing protein 8 (SET8) is a methyltransferase that selectively mono-methylates histone H4 at lysine residue 20, an event proven to have an important role in chromatin structure and transcriptional activation. It is also a regulator of p53, mono-methylating lysine 382 of the tumor suppressor. UNC0379...
| Schlagworte: | 6,7-dimethoxy-2-(1-pyrrolidinyl)-N-[5-(1-pyrrolidinyl)pentyl]-4-quinazolinamine |
| Anwendung: | SET8 inhibitor |
| CAS | 1620401-82-2 |
| MW: | 413.6 D |
ab 83,00 €
Anti-SETD8
Artikelnummer: BPS-25315
SETD8 (UniProtKB/Swiss Prot entry Q9NQR1) is a histone methyl transferase that specifically monomethylates Lys 20 of histone H4. This histone modification represents a specific tag for epigenetic transcriptional repression en is enriched during mitosis. SETD8 may also play a role in maintaining silent chromatin by...
| Schlagworte: | Anti-PRSET7, Anti-PR-Set7, Anti-PR/SET07, Anti-H4-K20-HMTase KMT5A, Anti-Lysine-specific methylase 5A, Anti-Lysine... |
| Anwendung: | WB |
| Spezies-Reaktivität: | human |
742,00 €
Set8, active human recombinant protein
Artikelnummer: BPS-51008
Active human SET8 (GenBank Accession No. NM_020382), (amino acids 195-352) with N-terminal GST tag, MW = 44 kDa, expressed in an E. coli expression system.
| Schlagworte: | PRSET7, PR-Set7, PR/SET07, H4-K20-HMTase KMT5A, Lysine-specific methylase 5A, Lysine N-methyltransferase 5A, SET... |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 44 kD |
491,00 €
SET8 (human recombinant)
Artikelnummer: Cay10319-100
Methylation of lysine can promote transcriptional activation or repression and is critical in regulating histone function. Lysine residues can be mono-, di-, or tri-methylated. SET8 selectively mono-methylates histone H4 at lysine 20, an event proven to have an important role in chromatin structure and...
| Schlagworte: | PRSET7, PR-Set7, PR-Set7, PR/SET07, PR/SET07, H4-K20-HMTase KMT5A, H4-K20-HMTase KMT5A, Lysine-specific methylase 5A,... |
| Anwendung: | Enzyme activity |
| Exprimiert in: | E.coli |
| MW: | 21.1 kD |
596,00 €
Anti-SETD8
Artikelnummer: 100-401-V82
Anti-SETD8 Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. Cross reactivity with SETD8 from species other than human and mouse not tested. Protein function: Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins....
| Schlagworte: | Anti-SETD8, Anti-KMT5A, Anti-PR-Set7, Anti-PR/SET07, EC=2.1.1.-, EC=2.1.1.43, Anti-H4-K20-HMTase SETD8, Anti-Lysine... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
690,00 €
Anti-SET07, clone 43AT551.86
Artikelnummer: NSJ-F40198-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. SET07 is a protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional...
| Schlagworte: | Anti-KMT5A, Anti-SETD8, Anti-PR-Set7, Anti-PR/SET07, EC=2.1.1.-, EC=2.1.1.43, Anti-H4-K20-HMTase SETD8, Anti-Lysine... |
| Anwendung: | IHC, IF, WB, ELISA |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse |
ab 361,00 €
Anti-SET07, clone 43AT890
Artikelnummer: NSJ-F40199-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. SET07 is a protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional...
| Schlagworte: | Anti-KMT5A, Anti-SETD8, Anti-PR-Set7, Anti-PR/SET07, EC=2.1.1.-, EC=2.1.1.43, Anti-H4-K20-HMTase SETD8, Anti-Lysine... |
| Anwendung: | WB, ELISA |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse |
ab 361,00 €
Anti-KMT5A
Artikelnummer: ATA-HPA064495.100
Protein function: Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin...
| Schlagworte: | Anti-PRSET7, Anti-PR-Set7, Anti-PR/SET07, Anti-H4-K20-HMTase KMT5A, Anti-Lysine-specific methylase 5A, Anti-Lysine... |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
PR-Set7 Protein, Human, Recombinant
Artikelnummer: TGM-TMPY-01584-100ug
Description: KMT5A (known as PR-Set7/9, SETD8 and SET8), a member of the SET domain containing methyltransferase family specifically targeting H4K20 for methylation, has been implicated in multiple biological processes. Inhibition of KMT5A attenuated proliferation and induced apoptosis. Elevated KMT5A expression was...
| Schlagworte: | KMT5A, SET domain containing (lysine methyltransferase) 8, SET07, PR-Set7, SET8 |
| MW: | 18.2 kD |
658,00 €
UNC0379
Artikelnummer: TGM-T1841-100mg
Description: UNC0379 is a selective, substrate-competitive inhibitor of the lysine methyltransferase (SETD8). Target: Histone Methyltransferase. Smiles: COc1cc2nc(nc(NCCCCCN3CCCC3)c2cc1OC)N1CCCC1. References: Ma A, et al. J Med Chem. 2014, 57(15), 6822-6833.
| Anwendung: | SET8 inhibitor |
| CAS | 1620401-82-2 |
| MW: | 413.56 D |
ab 45,00 €
NEU
![Anti-KMT5A [R05-7N6] Monoclonal Antibody](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg "Anti-KMT5A [R05-7N6] Monoclonal Antibody")
Anti-KMT5A [R05-7N6] Monoclonal Antibody
Artikelnummer: G-AGMB02938.20
KMT5A Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins (PubMed:12086618, PubMed:12121615, PubMed:15964846, PubMed:17707234, PubMed:27338793). Specifically...
| Schlagworte: | Anti-KMT5A, Anti-H4-K20-HMTase KMT5A, Anti-Lysine-specific methylase 5A, Anti-Lysine N-methyltransferase 5A, Anti-SET... |
| Anwendung: | WB, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
134,00 €