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Zu "K11425" wurden 29 Artikel gefunden!
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Artikelnummer: Cay27815-1
BI-9321 is an antagonist of the histone-lysine N-methyltransferase NSD3 (IC50 = 0.203 µM in a time-resolved FRET (TR-FRET) assay). It selectively binds to the NSD3 PWWP1 domain over 14 other PWWP domains, including NSD2-PWWP1 and NSD3-PWWP2, at 100 µM. BI-9321 is also selective for NSD3 over 20 methyllysine-binding...
| Schlagworte: | 4-[5-(7-fluoro-4-quinolinyl)-1-methyl-1H-imidazol-4-yl]-3,5-dimethyl-benzenemethanamine, trihydrochloride |
| Anwendung: | NSD3-PWWP1 antagonist |
| CAS | 2387510-87-2 |
| MW: | 469,8 D |
ab 72,00 €
Artikelnummer: G-CAB2317.100
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
398,00 €
Artikelnummer: ATA-HPA018893.100
Protein function: Histone methyltransferase. Preferentially dimethylates 'Lys- 4' and 'Lys-27' of histone H3 forming H3K2me2 and H3K27me2. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression. [The UniProt Consortium]...
| Schlagworte: | Anti-DC28, Anti-WHSC1L1, Anti-Protein whistle, Anti-WHSC1-like protein 1, Anti-Histone-lysine N-methyltransferase NSD3,... |
| Anwendung: | ChIP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 369,00 €
Artikelnummer: ATA-HPA005659.100
Protein function: Histone methyltransferase. Preferentially dimethylates 'Lys- 4' and 'Lys-27' of histone H3 forming H3K2me2 and H3K27me2. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression. [The UniProt Consortium]...
| Schlagworte: | Anti-DC28, Anti-WHSC1L1, Anti-Protein whistle, Anti-WHSC1-like protein 1, Anti-Histone-lysine N-methyltransferase NSD3,... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 369,00 €
Artikelnummer: NSJ-RQ6722
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Histone-lysine N-methyltransferase NSD3 is an enzyme that in humans is encoded by the WHSC1L1 gene. This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. This...
| Schlagworte: | Anti-DC28, Anti-WHSC1L1, Anti-Protein whistle, Anti-WHSC1-like protein 1, Anti-Histone-lysine N-methyltransferase NSD3,... |
| Anwendung: | WB, Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, monkey |
790,00 €
Artikelnummer: CSB-YP880145HU.1
Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 1-645aa. Protein Length: Full Length of Isoform 3. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MDFSFSFMQG IMGNTIQQPP QLIDSANIRQ EDAFDNNSDI AEDGGQTPYE ATLQQGFQYP ATTEDLPPLT NGYPSSISVY ETQTKYQSYN QYPNGSANGF GAVRNFSPTD YYHSEIPNTR...
| Schlagworte: | DC28, WHSC1L1, Protein whistle, WHSC1-like protein 1, Nuclear SET domain-containing protein 3, Histone-lysine... |
| Anwendung: | Activity not tested |
| Exprimiert in: | Yeast |
| Ursprungsart: | human |
| MW: | 73.9 kD |
ab 347,00 €
NEU
Artikelnummer: G-AGMB00296.20
NSD3 Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: Histone methyltransferase. Preferentially dimethylates 'Lys-4' and 'Lys-27' of histone H3 forming H3K4me2 and H3K27me2. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional...
| Schlagworte: | Anti-NSD3, Anti-Protein whistle, Anti-Histone-lysine N-methyltransferase NSD3, Anti-Nuclear SET domain-containing protein... |
| Anwendung: | WB, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
134,00 €
Artikelnummer: E-AN302026L.100
Wolf-Hirschhorn syndrome candidate 1-like protein 1 (WHSC1L1), also known as histone-lysine N-methyltransferase NSD3, is a SET domaincontaining histone methyltransferase protein that methylates histone H3 on lysine 4 (H3K4me) and lysine 27 (H3K27me) (1). Methylation of histone H3 lysine 4 is associated with...
| Schlagworte: | Anti-NSD3, Anti-Protein whistle, Anti-Histone-lysine N-methyltransferase NSD3, Anti-Nuclear SET domain-containing protein... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 304,00 €
Artikelnummer: ABS-RC-15440.100
Protein function: Histone methyltransferase. Preferentially dimethylates 'Lys- 4' and 'Lys-27' of histone H3 forming H3K2me2 and H3K27me2. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression. [The UniProt Consortium]
| Schlagworte: | Anti-DC28, Anti-WHSC1L1, Anti-Protein whistle, Anti-WHSC1-like protein 1, Anti-Nuclear SET domain-containing protein 3,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 206,00 €
Artikelnummer: ABS-PP-2723-L.100
Protein function: Histone methyltransferase. Preferentially dimethylates 'Lys- 4' and 'Lys-27' of histone H3 forming H3K2me2 and H3K27me2. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression. [The UniProt Consortium]
| Schlagworte: | Histone-lysine N-methyltransferase NSD3, Nuclear SET domain-containing protein 3, Protein whistle, WHSC1-like 1 isoform 9... |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 17.5 kD |
ab 115,00 €
Artikelnummer: VHPS-10007
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | DC28, NSD3, WHSC1L1, EC=2.1.1.43, Protein whistle, WHSC1-like protein 1, Histone-lysine N-methyltransferase NSD3, Nuclear... |
| Anwendung: | RNA quantification |
45,00 €
Artikelnummer: VMPS-7175
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | Nsd3, Whsc1l1, EC=2.1.1.43, WHSC1-like protein 1, Histone-lysine N-methyltransferase NSD3, Nuclear SET domain-containing... |
| Anwendung: | RNA quantification |
45,00 €