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Anti-Recombinant EHMT1, clone A405
Artikelnummer: E-AN301697L.100
Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also weakly methylates 'Lys-27' of histone H3...
| Schlagworte: | Anti-EHMT1, Anti-G9a-like protein 1, Anti-Lysine N-methyltransferase 1D, Anti-Histone H3-K9 methyltransferase 5,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 304,00 €
Anti-EHMT1
Artikelnummer: ATA-HPA067653.100
Rabbit Polyclonal EHMT1 Antibody against Human euchromatic histone lysine methyltransferase 1. Validated for Western Blot. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Interspecies information: Highest antigen sequence indentity to the following orthologs: ENSMUSG00000036893:...
| Schlagworte: | Anti-GLP, Anti-GLP1, Anti-EHMT1, Anti-EUHMTASE1, Anti-Eu-HMTase1, Anti-H3-K9-HMTase 5, Anti-G9a-like protein 1,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
UNC0638
Artikelnummer: Cay10734-1
The methylation of lysine residues on histones plays a central role in determining euchromatin structure and gene expression. The histone methyltransferase (HMTase) G9a can mono- or dimethylate lysine 9 on histone 3 (H3), contributing to early embryogenesis, genomic imprinting, and lymphocyte development. UNC0638 is...
| Schlagworte: | 2-cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine |
| Anwendung: | G9a HMTase inhibitor |
| CAS | 1255580-76-7 |
| MW: | 509.7 D |
ab 72,00 €
BIX01294 (hydrochloride hydrate)
Artikelnummer: Cay13124-1
The methylation of lysine residues on histones plays a central role in determining euchromatin structure and gene expression. The histone methyltransferase (HMTase) G9a can mono- or dimethylate lysine 9 on histone 3 (H3), contributing to early embryogenesis, genomic imprinting, and lymphocyte development. BIX01294...
| Schlagworte: | 2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine,... |
| Anwendung: | G9a HMTase inhibitor |
| CAS | 1808255-64-2 |
| MW: | 600 D |
ab 45,00 €
A-366
Artikelnummer: Cay16081-5
A-366 is a potent, peptide-competitive inhibitor of the lysine methyltransferase G9a (IC50 = 3.3 nM). It displays greater than 1,000-fold selectivity over 21 other methyltransferases. A-366 significantly reduces the cellular levels of dimethylation on histone 3 at lysine 9 (H3K9Me2) in PC3 cells without reducing...
| Schlagworte: | 5'-methoxy-6'-[3-(1-pyrrolidinyl)propoxy]-spiro[cyclobutane-1,3'-[3H]indol]-2'-amine |
| Anwendung: | EHMT2 inhibitor |
| CAS | 1527503-11-2 |
| MW: | 329.4 D |
ab 127,00 €
Anti-EHMT1
Artikelnummer: A301-642A
Protein function: Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also weakly methylates 'Lys-27'...
| Schlagworte: | Anti-GLP, Anti-GLP1, Anti-EHMT1, Anti-EUHMTASE1, EC=2.1.1.-, Anti-Eu-HMTase1, EC=2.1.1.43, Anti-H3-K9-HMTase 5,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
BIX 01294
Artikelnummer: AG-CR1-0051-M001
Selective and cell permeable G9a histone lysine methyltransferase (HMTase) inhibitor. Pluripotent stem cell inducer.
| Schlagworte: | 2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]4-quinazolinamine |
| Anwendung: | HMTase inhibitor |
| CAS | 935693-62-2 |
| MW: | 490,6 D |
ab 36,00 €
UNC0224
Artikelnummer: Cay13631-5
The methylation of lysine residues on histones plays a central role in determining euchromatin structure and gene expression. The histone methyltransferase (HMTase) G9a can mono- or dimethylate lysine 9 on histone 3 (H3), contributing to early embryogenesis, genomic imprinting, and lymphocyte development. UNC0224 is...
| Schlagworte: | 7-[3-(dimethylamino)propoxy]-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6-methoxy-N-(1-methyl-4-piperidinyl)-4-quinazolin... |
| Anwendung: | G9a HMTase inhibitor |
| CAS | 1197196-48-7 |
| MW: | 485.7 D |
ab 72,00 €
Anti-G9A/EHMT2
Artikelnummer: A300-933A
Protein function: Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also mediates monomethylation of...
| Schlagworte: | Anti-BAT8, Anti-EHMT2, EC=2.1.1.-, EC=2.1.1.43, Anti-Protein G9a, Anti-H3-K9-HMTase 3, Anti-HLA-B-associated transcript 8,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
UNC0642
Artikelnummer: Cay14604-1
The methylation of lysine residues on histones plays a central role in determining euchromatin structure and gene expression. The histone methyltransferases G9a and G9a-like protein (GLP) can mono- or dimethylate lysine 9 on histone 3, contributing to early embryogenesis, genomic imprinting, and lymphocyte...
| Schlagworte: | 2-(4,4-difluoropiperidin-1-yl)-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine |
| Anwendung: | EHMT1 / EHMT2 inhibitor |
| CAS | 1481677-78-4 |
| MW: | 546.7 D |
ab 93,00 €
UNC0631
Artikelnummer: Cay11084-10
UNC0631 is a potent and selective inhibitor of G9a activity in vitro (IC50 = 4 nM) and G9a/GLP-mediated dimethylation of histone 3 on lysine 9 in MDA-MB-231 cells (IC50 = 25 nM). It potently inhibits G9a/GLP activity in a variety of cancer cell lines as well as in the human fetal lung IMR-90 cell line.Formal Name:...
| Schlagworte: | N-[1-(cyclohexylmethyl)-4-piperidinyl]-2-[hexahydro-4-(1-methylethyl)-1H-1,4-diazepin-1-yl]-6-methoxy-7-[3-(1-piperidinyl)... |
| Anwendung: | Potent, selective EHMT1 / EHMT2 inhibitor |
| CAS | 1320288-19-4 |
| MW: | 635.9 D |
ab 56,00 €
EHMT1 (GLP), human recombinant protein
Artikelnummer: BPS-51020
Human euchromatic histone-lysine N-methyltransferase (EHMT1), also known as G9a-like protein (GLP) or KMT1D, GenBank Accession No. NM_024757, a.a. 894-1298 (end) with N-terminal GST-tag, MW= 72.4 kDa, expressed in an E. coli expression system.
| Schlagworte: | GLP, GLP1, EHMT1, EUHMTASE1, Eu-HMTase1, H3-K9-HMTase 5, G9a-like protein 1, Lysine N-methyltransferase 1D, Histone H3-K9... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 72.4 kD |
663,00 €