Zu "K11416" wurden 68 Artikel gefunden!
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Anti-SIRT6 / Sirtuin 6
Artikelnummer: NSJ-FY13069
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. SIRT6 antibody detects Sirtuin 6, a nuclear NAD+-dependent deacetylase that regulates genomic stability, metabolism, and lifespan. The UniProt recommended name is NAD-dependent protein deacylase sirtuin 6 (SIRT6). This enzyme belongs to the...
| Schlagworte: | Anti-SIRT6, Anti-SIR2-like protein 6, Anti-Regulatory protein SIR2 homolog 6, Anti-NAD-dependent protein deacylase... |
| Anwendung: | ELISA, FC, IF, ICC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
790,00 €
SIRT6 (human, recombinant)
Artikelnummer: Cay10315-100
The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) and have been shown to catalyze a reaction that couples lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose from NAD+ and the abstracted acetyl group. There are seven human sirtuins,...
| Schlagworte: | SIRT6, SIR2L6, SIR2-like protein 6, SIR2-like protein 6, Regulatory protein SIR2 homolog 6, Regulatory protein SIR2... |
| Anwendung: | Enzyme kinetics, inhibitor screening |
659,00 €
UBCS039
Artikelnummer: Cay43478-1
A SIRT6 activator, increases the deacetylation of an acetylated H3K9 peptide in a cell-free assay (EC50 = ~38 µM), selectively activates SIRT6 deacetylation activity over SIRT1, SIRT2, and SIRT3 deacetylation activities but does increase SIRT5 desuccinylation activity at 100 µM, active against M. tuberculosis (MIC =...
| Schlagworte: | 4,5-dihydro-4-(3-pyridinyl)-pyrrolo[1,2-a]quinoxaline |
| Anwendung: | SIRT6 activator |
| CAS | 358721-70-7 |
| MW: | 247.3 D |
ab 44,00 €
Sirtuin 6, active human recombinant protein
Artikelnummer: BPS-50017
Active human Sirtuin 6 (GenBank Accession No. NM_016539), full length with N-terminal GST tag, MW= 65 kDa, expressed in E. coli expression system.
| Schlagworte: | hSIRT6, SIR2L6, SIR2-like protein 6, Regulatory protein SIR2 homolog 6, NAD-dependent protein deacylase sirtuin-6,... |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 65 kD |
663,00 €
Anti-Sirt6
Artikelnummer: A302-452A
Protein function: NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a...
| Schlagworte: | Anti-SIRT6, Anti-SIR2L6, EC=3.5.1.-, Anti-SIR2-like protein 6, Anti-Regulatory protein SIR2 homolog 6, Anti-NAD-dependent... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-Sirtuin 6 (human), clone S6R82-2
Artikelnummer: AG-20A-0091-C100
Recognizes human sirtuin 6. Detects a band of about 47kDa by Western blot. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. Sirtuin-6 is a NAD-dependent protein deacetylase with activity towards 'Lys-9'and 'Lys-56'of histone H3. Modulates acetylation of histone H3 in telomeric chromatin...
| Schlagworte: | SIRT6, , NAD-dependent Deacetylase Sirtuin-6, Mono-ADP-ribosyltransferase Sirtuin 6, SIR2-like Protein 6, SIR2L6 |
| Anwendung: | ELISA, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 127,00 €
MDL 800
Artikelnummer: Cay35528-5
MDL 800 is an allosteric activator of sirtuin 6 (SIRT6). It selectively activates SIRT6 deacetylase activity over SIRT1-5 and -7 and histone deacetylase 1 (HDAC1) and HDAC2-11 deacetylase activity in cell-free assays at 100 µM. It induces histone deacetylation (IC50 = 23.3 µM) in, and reduces proliferation of,...
| Schlagworte: | 2-[[(5-bromo-4-fluoro-2-methylphenyl)amino]sulfonyl]-5-[[(3,5-dichlorophenyl)sulfonyl]amino]-benzoic acid, methyl ester |
| Anwendung: | Allosteric SIRT6 activator |
| CAS | 2275619-53-7 |
| MW: | 626.3 D |
ab 75,00 €
Anti-Sirtuin 6 (human)
Artikelnummer: AG-25A-0101-C100
Recognizes human sirtuin 6. Detects a band of about 42kDa by Western blot. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. Sirtuin-6 is a NAD-dependent protein deacetylase with activity towards 'Lys-9'and 'Lys-56'of histone H3. Modulates acetylation of histone H3 in telomeric chromatin...
| Schlagworte: | SIRT6, , NAD-dependent Deacetylase Sirtuin-6, Mono-ADP-ribosyltransferase Sirtuin 6, SIR2-like Protein 6, SIR2L6 |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
182,00 €
Anti-SIRT6, clone 6C9-D10-D3
Artikelnummer: ARG56580.100
Protein function: NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a...
| Schlagworte: | Anti-SIRT6, Anti-SIR2L6, EC=3.5.1.-, Anti-SIR2-like protein 6, Anti-Regulatory protein SIR2 homolog 6, Anti-NAD-dependent... |
| Anwendung: | WB, ICC, IF, IP |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat, monkey |
658,00 €
Anti-Sirt6
Artikelnummer: A302-451A
Protein function: NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a...
| Schlagworte: | Anti-SIRT6, Anti-SIR2L6, EC=3.5.1.-, Anti-SIR2-like protein 6, Anti-Regulatory protein SIR2 homolog 6, Anti-NAD-dependent... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Sirtuin 6 Fluorogenic Assay Kit
Artikelnummer: BPS-50022
The Sirtuin 6 Fluorogenic Assay Kit is a complete assay system designed to measure SIRT6 activity for screening and profiling applications. It comes in a convenient 96-well format, with all the reagents necessary for 100 fluorescent SIRT6 activity measurements. In addition, the kit includes purified SIRT6 enzyme and...
| Schlagworte: | hSIRT6, SIR2L6, SIR2-like protein 6, Regulatory protein SIR2 homolog 6, NAD-dependent protein deacylase sirtuin-6,... |
| Anwendung: | Enzyme kinetics, drug discovery, HTS |
| Spezies-Reaktivität: | human |
700,00 €
Human SIRT6 ELISA Kit
Artikelnummer: G-HUFI01781.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €