Zu "K11416" wurden 60 Artikel gefunden!
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Anti-SIRT6
Artikelnummer: ABS-KC-6283.100
Protein function: NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a...
| Schlagworte: | Anti-NAD-dependent protein deacylase sirtuin-6, Anti-NAD-dependent protein deacetylase sirtuin-6, Anti-Protein... |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat, monkey |
ab 232,00 €
MDL-800
Artikelnummer: TGM-T64529-100mg
Description: MDL-800 is a SIRT6 modulator with antitumor activity for the study of hepatocellular carcinoma and non-small cell lung cancer. Target: Sirtuin. Smiles: COC(=O)c1cc(NS(=O)(=O)c2cc(Cl)cc(Cl)c2)ccc1S(=O)(=O)Nc1cc(Br)c(F)cc1C. References: Shang JL, et al. MDL-800, an allosteric activator of SIRT6,...
| Schlagworte: | MDL800, MDL 800 |
| Anwendung: | Allosteric SIRT6 activator |
| CAS | 2275619-53-7 |
| MW: | 626.3 D |
ab 52,00 €
OSS_128167
Artikelnummer: TGM-T4328-100mg
Description: OSS_128167 (SIRT6-IN-1) is a specific SIRT6 inhibitor, and for SIRT6(IC50=89 µM), SIRT1(IC50=1578 µM) and SIRT2(IC50=751 µM). Target: HBV, Sirtuin. Smiles: OC(=O)c1cc(NC(=O)c2cccc(NC(=O)c3ccco3)c2)ccc1O. References: Parenti MD, et al. Discovery of novel and selective SIRT6 inhibitors. J Med Chem. 2014...
| Schlagworte: | SIRT6-IN-1 |
| Anwendung: | SIRT6 inhibitor |
| CAS | 887686-02-4 |
| MW: | 366.32 D |
ab 40,00 €
SIRT6 Protein, Human, Recombinant (GST)
Artikelnummer: TGM-TMPH-01742-100ug
Description: SIRT6 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 66.0 kDa and the accession number is Q8N6T7.
| Schlagworte: | SIR2-like protein 6, NAD-dependent protein deacylase sirtuin-6, SIRT6, Regulatory protein SIR2 homolog 6, NAD-dependent... |
| MW: | 66.0 kD |
ab 198,00 €
SIRT6 (human, recombinant)
Artikelnummer: Cay10315-100
The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) and have been shown to catalyze a reaction that couples lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose from NAD+ and the abstracted acetyl group. There are seven human sirtuins,...
| Schlagworte: | SIRT6, SIR2L6, SIR2-like protein 6, SIR2-like protein 6, Regulatory protein SIR2 homolog 6, Regulatory protein SIR2... |
| Anwendung: | Enzyme kinetics, inhibitor screening |
608,00 €
Anti-SIRT6
Artikelnummer: CSB-PA959450.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SIRT6. Antigen Species: Human
| Schlagworte: | Anti-SIRT6, Anti-SIR2L6, EC=2.3.1.286, Anti-SIR2-like protein 6, Anti-Regulatory protein SIR2 homolog 6,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 167,00 €
NAD-dependent protein deacetylase sirtuin-6 (SIRT6),...
Artikelnummer: CSB-EP854057HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 2-355aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal GST-tagged. Target Protein Sequence: SVNYAAGLSP YADKGKCGLP EIFDPPEELE RKVWELARLV WQSSSVVFHT GAGISTASGI PDFRGPHGVW TMEERGLAPK FDTTFESARP TQTHMALVQL ERVGLLRFLV SQNVDGLHVR...
| Schlagworte: | SIRT6, SIR2L6, EC=2.3.1.286, SIR2-like protein 6, Regulatory protein SIR2 homolog 6, NAD-dependent protein deacetylase... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 66 kD |
ab 219,00 €
Anti-SIRT6
Artikelnummer: CSB-PA113703.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SIRT6. Antigen Species: Human
| Schlagworte: | Anti-SIRT6, Anti-SIR2L6, EC=2.3.1.286, Anti-SIR2-like protein 6, Anti-Regulatory protein SIR2 homolog 6,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 167,00 €
Sirtuin 6, active human recombinant protein
Artikelnummer: BPS-50017
Active human Sirtuin 6 (GenBank Accession No. NM_016539), full length with N-terminal GST tag, MW= 65 kDa, expressed in E. coli expression system.
| Schlagworte: | hSIRT6, SIR2L6, SIR2-like protein 6, Regulatory protein SIR2 homolog 6, NAD-dependent protein deacylase sirtuin-6,... |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 65 kD |
663,00 €
Anti-Sirt6
Artikelnummer: A302-452A
Protein function: NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a...
| Schlagworte: | Anti-SIRT6, Anti-SIR2L6, EC=3.5.1.-, Anti-SIR2-like protein 6, Anti-Regulatory protein SIR2 homolog 6, Anti-NAD-dependent... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 178,00 €
Anti-Sirtuin 6 (human), clone S6R82-2
Artikelnummer: AG-20A-0091-C100
Recognizes human sirtuin 6. Detects a band of about 47kDa by Western blot. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. Sirtuin-6 is a NAD-dependent protein deacetylase with activity towards 'Lys-9'and 'Lys-56'of histone H3. Modulates acetylation of histone H3 in telomeric chromatin...
| Schlagworte: | SIRT6, , NAD-dependent Deacetylase Sirtuin-6, Mono-ADP-ribosyltransferase Sirtuin 6, SIR2-like Protein 6, SIR2L6 |
| Anwendung: | ELISA, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 116,00 €
MDL 800
Artikelnummer: Cay35528-5
MDL 800 is an allosteric activator of sirtuin 6 (SIRT6). It selectively activates SIRT6 deacetylase activity over SIRT1-5 and -7 and histone deacetylase 1 (HDAC1) and HDAC2-11 deacetylase activity in cell-free assays at 100 µM. It induces histone deacetylation (IC50 = 23.3 µM) in, and reduces proliferation of,...
| Schlagworte: | 2-[[(5-bromo-4-fluoro-2-methylphenyl)amino]sulfonyl]-5-[[(3,5-dichlorophenyl)sulfonyl]amino]-benzoic acid, methyl ester |
| Anwendung: | Allosteric SIRT6 activator |
| CAS | 2275619-53-7 |
| MW: | 626.3 D |
ab 69,00 €