Zu "K11413" wurden 73 Artikel gefunden!
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SIRT3 Direct Fluorescent Screening Assay Kit
Artikelnummer: Cay10011566-96
The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) that catalyze a reaction coupling lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose. SIRT3 is a mitochondrial protein that plays a role in metabolic regulation and other cellular...
| Schlagworte: | SIRT3, hSIRT3, SIR2L3, EC=3.5.1.-, SIR2-like protein 3, NAD-dependent deacetylase sirtuin-3, mitochondrial |
| Anwendung: | SIRT3 activator/inhibitor screening |
| Spezies-Reaktivität: | human |
516,00 €
Sirtuin 3, active human recombinant protein
Artikelnummer: BPS-50014
Active human Sirtuin 3 (GenBank Accession No. NM_012239), amino acids 102- 399 with N-terminal GST tag, MW= 59 kDa, expressed in E. coli expression system.
| Schlagworte: | SIRT3, SIR2L3, hSIRT3, SIR2-like protein 3, Regulatory protein SIR2 homolog 3, NAD-dependent protein deacetylase... |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 59 kD |
663,00 €
SIRT3 (human, recombinant)
Artikelnummer: Cay10011194-100
The sirtuins (SIRTs) represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) and have been shown to catalyze a reaction that couples lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose from NAD+ and the abstracted acetyl group. There are seven human...
| Schlagworte: | SIRT3, SIR2L3, hSIRT3, hSIRT3, SIR2-like protein 3, SIR2-like protein 3, Regulatory protein SIR2 homolog 3, Regulatory... |
| Anwendung: | WB |
| MW: | 37 kD |
712,00 €
3-TYP
Artikelnummer: Cay29660-100
3-TYP is a sirtuin 3 (SIRT3) inhibitor (IC50 = 38 µM). It is selective for SIRT3 over SIRT1 and SIRT2 at 1 mM. 3-TYP (1 mM) increases acetylation of lysine residues in mitochondrial proteins in HeLa cells. It inhibits the growth of CCRF-CEM, COLO 205, OVCAR-4, OVCAR-8, and SKOV3 cells by greater than 50% when used...
| Schlagworte: | 3-(1H-1,2,3-triazol-5-yl)-pyridine |
| Anwendung: | SIRT3 inhibitor |
| CAS | 120241-79-4 |
| MW: | 146.2 D |
ab 102,00 €
Anti-SIRT3
Artikelnummer: ARG54659.50
Protein function: NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA and the ATP synthase subunit ATP5O. Contributes to the regulation of the cellular energy metabolism....
| Schlagworte: | Anti-SIRT3, Anti-hSIRT3, Anti-SIR2L3, EC=3.5.1.-, Anti-SIR2-like protein 3, Anti-Regulatory protein SIR2 homolog 3,... |
| Anwendung: | ELISA, WB |
| Wirt: | Chicken |
| Spezies-Reaktivität: | human, mouse, rat |
625,00 €
Anti-SIRT3, C-terminal
Artikelnummer: ARG63826.100
Protein function: NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA and the ATP synthase subunit ATP5O. Contributes to the regulation of the cellular energy metabolism....
| Schlagworte: | Anti-SIRT3, Anti-SIR2L3, Anti-hSIRT3, EC=3.5.1.-, Anti-SIR2-like protein 3, Anti-Regulatory protein SIR2 homolog 3,... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Sirt3 Assay Kit
Artikelnummer: BPS-50088
The Fluorogenic SIRT3 Assay Kit is a complete assay system designed to measure Sirtuin 3 (SIRT3) activity for screening and profiling applications. It comes in a convenient 96-well format, with all the reagents necessary for 32 fluorescent SIRT3 activity measurements*. The kit includes purified SIRT3 enzyme and a...
| Schlagworte: | SIRT3, SIR2L3, hSIRT3, SIR2-like protein 3, Regulatory protein SIR2 homolog 3, NAD-dependent protein deacetylase... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
700,00 €
Mouse Sirt3 ELISA Kit
Artikelnummer: G-MOFI00537.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
698,00 €
Anti-SIRT3
Artikelnummer: 200-901-EL8
Anti-SIRT3 Antibody is an IgY fraction antibody purified from monospecific chicken egg yolks by a multi-step process which includes selective precipitation and salt fractionation followed by extensive dialysis against the buffer stated above. Cross reactivity with SIRT3 from other sources has not been determined....
| Schlagworte: | Anti-SIRT3, Anti-hSIRT3, Anti-SIR2L3, EC=3.5.1.-, Anti-SIR2-like protein 3, Anti-Regulatory protein SIR2 homolog 3,... |
| Anwendung: | ELISA, WB |
| Wirt: | Chicken |
| Spezies-Reaktivität: | human, mouse, rat |
848,00 €
Anti-SIRT3
Artikelnummer: NSJ-R35426-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Sirtuin (silent mating type information regulation 2 homolog) 3 Protein function: NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key...
| Schlagworte: | Anti-SIRT3, Anti-hSIRT3, Anti-SIR2L3, EC=3.5.1.-, Anti-SIR2-like protein 3, Anti-Regulatory protein SIR2 homolog 3,... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
Anti-Sirt3
Artikelnummer: NSJ-R35542-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Sirtuin 3 Protein function: NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH,...
| Schlagworte: | Anti-SIRT3, Anti-hSIRT3, Anti-SIR2L3, EC=3.5.1.-, Anti-SIR2-like protein 3, Anti-Regulatory protein SIR2 homolog 3,... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, mouse |
836,00 €
CAY10722
Artikelnummer: Cay22404-1
CAY10722 is an inhibitor of sirtuin 3 (SIRT3), a class III HDAC (71% inhibition at 200 µM). SIRT3 is involved in modulating metabolic homeostasis as a NAD+-dependent protein deacetylase in the mitochondria. SIRT3 functions as either an oncogene or tumor suppressor, depending on cancer cell type. High SIRT3...
| Schlagworte: | N-[2-(2,4-dichlorophenyl)-5-benzoxazolyl]-benzeneacetamide |
| Anwendung: | SIRT3 inhibitor |
| CAS | 388086-13-3 |
| MW: | 397.3 D |
ab 49,00 €