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Zu "K11411" wurden 125 Artikel gefunden!
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Artikelnummer: E-BC-F056.48
Detection principle: This kit uses the fluorescence resonance energy transfer (FRET) method for detection. After deacetylation by SIRT-1, the fluorescent substrate generates an activated fluorescent substrate, which can be decomposed by proteases to produce fluorescent substances. The maximum excitation wavelength...
Schlagworte: | SIR2L1, Sirtuin 1 (SIRT-1) Activity Assay Kit |
ab 376,00 €
Artikelnummer: NSJ-RQ5549
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Sirtuin 1, also known as SIR2L1 or SIRT1, is a protein that in humans is encoded by the SIRT1 gene. It is mapped to 10q21.3. Sirtuin 1 is a member of the sirtuin family of proteins, homologs of the Sir2 gene in S. cerevisiae. Members of the sirtuin family are...
Schlagworte: | Anti-SIR2L1, SIRT1 Antibody |
Anwendung: | WB, IHC (paraffin), IF, FC, Direct ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
755,00 €
Artikelnummer: ELK-ELK6397.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse SIRT1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse SIRT1. Next,...
Schlagworte: | Sirt1, Sir2l1 |
Anwendung: | ELISA |
Spezies-Reaktivität: | mouse |
ab 365,00 €
Artikelnummer: ELK-ELK3255.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human SIRT1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human SIRT1. Next,...
Schlagworte: | SIR2L1 |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: Cay10010401-96
Sirtuins (SIRTs) represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs). Human SIRT1 is the homolog of yeast Silent information regulator 2 (Sir2) and has been shown to regulate the activity of the p53 tumor suppressor and inhibit apoptosis. Small molecule activators of SIRT1,...
Schlagworte: | SIRT1, hSIR2, hSIRT1, SIR2L1, EC=3.5.1.-, SIR2-like protein 1, NAD-dependent deacetylase sirtuin-1 |
Anwendung: | SIRT1 inhibitor/activator screening |
Spezies-Reaktivität: | human |
467,00 €
Artikelnummer: BPS-50081
The Fluorogenic SIRT1 Assay Kit is a complete assay system designed to measure Sirtuin 1 (SIRT1) activity for screening and profiling Applications. It comes in a convenient 96-well format, with all the reagents necessary for 100 fluorescent SIRT1 (Sir2) activity measurements. In addition, the kit includes purified...
Schlagworte: | SIR2L1, |
Anwendung: | Enzyme kinetics, inhibitor screening, HTS |
657,00 €
Artikelnummer: Cay10009798-5
EX-527 is an inhibitor of sirtuin 1 (SIRT1, IC50 = 0.098 µM). It is selective for SIRT1 over SIRT2, and SIRT3 (IC50s = 19.6 and 48.7 µM, respectively) and the cytochrome P450 (CYP) isoforms CYP3A4, CYP2D6, CYP2C9, CYP2C19, and CYP1A2 at 1 µM. EX-527 (50 µM) induces cell cycle arrest at the G1 phase in MCF-7...
Schlagworte: | 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide |
Anwendung: | SIRT1 inhibitor |
CAS | 49843-98-3 |
MW: | 248.7 D |
ab 43,00 €
Artikelnummer: Cay10009797-1
Sirtuins (SIRTs) represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs). Human SIRT1 is the homolog of yeast silent information regulator 2 (Sir2) and has been shown to regulate the activity of the p53 tumor suppressor and inhibit apoptosis. Small molecule activators of SIRT1,...
Schlagworte: | SIRT1 Activator 3, Sirtuin 1 Activator 3,... |
Anwendung: | SIRT1 assays |
CAS | 839699-72-8 |
MW: | 367.5 D |
ab 86,00 €
Artikelnummer: Cay15246-100
Fisetin is a flavonoid that has been found in various fruits and vegetables and has diverse biological activities. It scavenges radicals in a Trolox equivalent antioxidant capacity (TEAC) assay and inhibits oxidative burst induced by N-formyl-methionyl-leucyl-phenylalanine (fMLP, Cay-21495) in isolated human...
Schlagworte: | CI-75620, NSC 407010, NSC 656275, 2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4H-1-benzopyran-4-one |
Anwendung: | Sirtuin 1 activator, Antioxidant |
CAS | 528-48-3 |
MW: | 286.2 D |
ab 43,00 €
Artikelnummer: BPS-50012
Active human Sirtuin 1 , GenBank Accession No. NM_012238), amino acids 193- 741 with N-terminal GST tag, MW= 87.2 kDa, expressed in E. coli expression system.
Schlagworte: | SIR2L1, |
Anwendung: | Enzyme kinetics, inhibitor screening |
MW: | 87.2 kD |
650,00 €
Artikelnummer: Cay10011190-100
The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) and have been shown to catalyze a reaction that couples lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose from NAD+ and the abstracted acetyl group. There are seven human sirtuins,...
Schlagworte: | hSIR2, SIR2L1, hSIRT1, 75SirT1, SIR2-like protein 1, SirtT1 75 kDa fragment, Regulatory protein SIR2 homolog 1,... |
Anwendung: | Enzyme activity |
MW: | 89,2 kD |
642,00 €
Artikelnummer: CDX-R0057-M100
White to off-white powder. Soluble in ethanol, DMSO, acetone or water (3 mg/100 ml). Selective inhibitor of COX?1. Resveratrol is a phenolic phytoalexin found in grape skin and other plants. It has intracellular antioxidant activity and activates SIRT1, a NAD+-dependent histone deacetylase involved in mitochondrial...
Schlagworte: | 3,4',5-Trihydroxy-trans-stilbene |
Anwendung: | Selective COX?1 inhibitor, Antioxidant, SIRT1 activator |
CAS | 501-36-0 |
MW: | 228,24 D |
ab 77,00 €