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Human HDAC4 (Histone Deacetylase 4) ELISA Kit
Artikelnummer: ELK-ELK4669.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human HDAC4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human HDAC4. Next,...
| Schlagworte: | HD4, KIAA0288, Histone deacetylase 4 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Human HDAC5 (Histone Deacetylase 5) ELISA Kit
Artikelnummer: ELK-ELK4712.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human HDAC5. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human HDAC5. Next,...
| Schlagworte: | HD5, HDAC5, KIAA0600, EC=3.5.1.98, Antigen NY-CO-9, Histone deacetylase 5 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Mouse HDAC4 (Histone Deacetylase 4) ELISA Kit
Artikelnummer: ELK-ELK6923.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse HDAC4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse HDAC4. Next,...
| Schlagworte: | HD4, Hdac4, Histone deacetylase 4 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
Panobinostat
Artikelnummer: Cay13280-5
Panobinostat is a pan-inhibitor of histone deacetylases (HDACs, Kis = 0.6-31 nM for HDAC1-11). It inhibits growth in a panel of 37 human or mouse lung cancer cell lines, including small cell lung cancer (SCLC), non-small cell lung cancer (NSCLC), and mesothelioma cells (IC50s = 4-175, 5-310, and 5-470 nM,...
| Schlagworte: | LBH-589, (2E)-N-hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide |
| Anwendung: | HDAC inhibitor |
| CAS | 404950-80-7 |
| MW: | 349.4 D |
ab 39,00 €
HDAC-4, active human recombinant protein
Artikelnummer: BPS-50004
Active human HDAC4 , GenBank Accession No. NM_006037, amino acids 627- 1085 with N-terminal GST tag, MW= 75.2 kDa, expressed in baculovirus expression system.
| Schlagworte: | HD4, KIAA0288, Histone deacetylase 4, |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 75.2 kD |
679,00 €
TMP269
Artikelnummer: Cay17738-1
While class I HDACs are localized predominantly within the nucleus, class II HDACs shuttle into and out of the nucleus in response to intracellular signaling. Class IIa HDACs, which include HDAC4, 5, 7, and 9, commonly act as corepressors and play diverse roles in cell biology. TMP269 is a cell-permeable inhibitor...
| Schlagworte: | N-[[tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]-benzamide |
| Anwendung: | Cell-permeable class IIa HDAC inhibitor |
| CAS | 1314890-29-3 |
| MW: | 514.5 D |
ab 50,00 €
HDAC-5, active human recombinant protein
Artikelnummer: BPS-50005
Active human HDAC5 catalytic domain , GenBank Accession No. NM_001015053, amino acid 657-1123 with C-terminal His tag, MW= 51 kDa, expressed in baculovirus expression system.
| Schlagworte: | HD5, HDAC5, KIAA0600, EC=3.5.1.98, Antigen NY-CO-9, Histone deacetylase 5, |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 51 kD |
650,00 €
MC 1568
Artikelnummer: Cay16265-1
While class I HDACs are localized predominantly within the nucleus, class II HDACs shuttle into and out of the nucleus in response to intracellular signaling. Class IIa HDACs, which includes HDAC4, 5, 7, and 9, commonly act as corepressors and play diverse roles in cell biology. MC 1568 is a selective inhibitor of...
| Schlagworte: | (2E)-3-[5-[(1E)-3-(3-fluorophenyl)-3-oxo-1-propen-1-yl]-1-methyl-1H-pyrrol-2-yl]-N-hydroxy-2-propenamide |
| Anwendung: | Selective class IIa HDAC inhibitor |
| CAS | 852475-26-4 |
| MW: | 314.3 D |
ab 43,00 €
LMK 235
Artikelnummer: Cay14969-1
Histone deacetylases (HDACs) catalyze the hydrolytic removal of acetyl groups from histone lysine residues, which commonly results in chromatin condensation and transcriptional repression. LMK 235 is an HDAC inhibitor that selectively targets HDACs 4 and 5 (IC50s = 12 and 4 nM, respectively) over other HDACs (IC50s...
| Schlagworte: | N-[[6-(hydroxyamino)-6-oxohexyl]oxy]-3,5-dimethyl-benzamide |
| Anwendung: | HDAC4 inhibitor, HDAC5 inhibitor |
| CAS | 1418033-25-6 |
| MW: | 294.4 D |
ab 50,00 €
TMP-195
Artikelnummer: Cay23242-5
TMP-195 is an inhibitor of class IIa histone deacetylases (HDACs, Kis = 59, 60, 26, and 15 nM for HDAC4, 5, 7, and 9, respectively). It is selective for class IIa HDACs over class I and class IIb HDACs (Kis = 10-43 µM for HDAC1-3, 6, 9, and 10-11). TMP-195 blocks accumulation of chemoattractant chemokine ligand 2...
| Schlagworte: | N-[2-methyl-2-(2-phenyl-4-oxazolyl)propyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]-benzamide |
| Anwendung: | Class IIa HDAC inhibitor |
| CAS | 1314891-22-9 |
| MW: | 456.4 D |
ab 43,00 €
HDAC4 Fluorogenic Assay Kit
Artikelnummer: BPS-50064
The Fluorogenic HDAC4 Assay Kit is a complete assay system designed to measure histone deacetylase 4 (HDAC4) activity for screening and profiling applications. It comes in a convenient 96-well format, with all the reagents necessary for 100 fluorescent HDAC4 activity measurements. In addition, the kit includes...
| Schlagworte: | HD4, KIAA0288, Histone deacetylase 4, |
| Anwendung: | Enzyme kinetics, inhibitor screening, HTS |
| Spezies-Reaktivität: | human |
686,00 €
HDAC5 (human, recombinant)
Artikelnummer: Cay10009379-1
Histone deacetylase 5 (HDAC) is a zinc-dependent metalloenzyme and class IIa HDAC. It is composed of an N-terminal regulatory domain, which contains a myocyte-specific enhancer factor 2 (MEF2) binding site, two 14-3-3 binding sites, and a nuclear localization signal, a catalytic domain, and a C-terminal domain that...
| Schlagworte: | Histone Deacetylase 5 |
| Anwendung: | Enzyme activity |
| MW: | 51 D |
648,00 €