Zu "K11404" wurden 108 Artikel gefunden!
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NEU
Anti-Recombinant HDAC3, clone C111913
Artikelnummer: E-AN302293L.100
Protein function: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates (PubMed:21030595, PubMed:21444723, PubMed:23911289, PubMed:25301942, PubMed:28167758, PubMed:28497810, PubMed:32404892,...
| Schlagworte: | Anti-HDAC3, Anti-SMAP45, Anti-RPD3-2, Anti-Histone deacetylase 3, Anti-Protein deacylase HDAC3, Anti-Protein deacetylase... |
| Anwendung: | WB, IHC, IF, IP, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human,mouse,rat |
ab 171,00 €
NEU
Anti-Recombinant HDAC3, clone C112825
Artikelnummer: E-AN303205L.100
Protein function: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates (PubMed:21030595, PubMed:21444723, PubMed:23911289, PubMed:25301942, PubMed:28167758, PubMed:28497810, PubMed:32404892,...
| Schlagworte: | Anti-HDAC3, Anti-SMAP45, Anti-RPD3-2, Anti-Histone deacetylase 3, Anti-Protein deacylase HDAC3, Anti-Protein deacetylase... |
| Anwendung: | WB, IHC, ICC/IF, FCM, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human,mouse,rat |
ab 171,00 €
Mouse HDAC3 (Histone Deacetylase 3) ELISA Kit
Artikelnummer: ELK-ELK11427.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse HDAC3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse HDAC3. Next,...
| Schlagworte: | Hdac3, Histone deacetylase 3, Protein deacylase HDAC3, Protein deacetylase HDAC3 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 374,00 €
HD-TAC7
Artikelnummer: Cay45613-1
HD-TAC7 is a proteolysis-targeting chimera (PROTAC) composed of a class I histone deacetylase (HDAC) inhibitor linked to the cereblon ligand pomalidomide (Cay19877). It binds to HDAC1, HDAC2, and HDAC3 (IC50s = 3.6, 4.2, and 1.1 µM, respectively) and induces degradation of HDAC3 in RAW 264.7 cells with a...
| Schlagworte: | N-(2-amino-4-fluorophenyl)-4-[[5-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]acetyl]-am... |
| Anwendung: | HDAC3 degradation driving PROTAC |
| CAS | 2978763-95-8 |
| MW: | 657.66 D |
ab 278,00 €
HDAC-3/NcoR2 Complex, active human recombinant proteins
Artikelnummer: BPS-50003
Active complex of human HDAC3 , GenBank Accession No. NM_003883, full length with C-terminal His tag, MW= 49.7 kDa, and human NCOR2 , amino acid 395- 489, GenBank Accession No. NM_006312, N-terminal GST tag, MW= 37.6 kDa, co-expressed in baculovirus expression system.
| Schlagworte: | HD3, HDAC3, RPD3-2, SMAP45, Histone deacetylase 3, Protein deacylase HDAC3, Protein deacetylase HDAC3, |
| Anwendung: | Enzyme kinetics, inhibitor screening |
730,00 €
Anti-HDAC3
Artikelnummer: NSJ-R30679
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Histone deacetylase 3 is a member of the histone deacetylase/acuc/apha family of proteins and is an enzyme that in humans is encoded by the HDAC3 gene. The enzyme has histone deacetylase activity and represses transcription when tethered to a promoter. It may...
| Schlagworte: | Anti-HDAC3, Anti-RPD3-2, Anti-SMAP45, Anti-Histone deacetylase 3, Anti-Protein deacylase HDAC3, Anti-Protein deacetylase... |
| Anwendung: | WB, IHC (paraffin), (IF), ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Apicidin
Artikelnummer: Cay10575-1
Apicidin is a cyclic tetrapeptide that has been found in F. pallidoroseum and has diverse biological activities. It is active against E. tenella, T. gondii, P. falciparum, C. parvum, N. caninum, B. jellisoni, and C. bigenetica (MICs = 62, 8, 125, 30, 15, 4, and 8 ng/ml, respectively) and decreases the percentage of...
| Schlagworte: | OSI 2040, cyclo[(2S)-2-amino-8-oxodecanoyl-1-methoxy-L-tryptophyl-L-isoleucyl-(2R)-2-piperidinecarbonyl] |
| Anwendung: | HDAC inhibitor |
| CAS | 183506-66-3 |
| MW: | 623.8 D |
ab 93,00 €
RGFP966
Artikelnummer: Cay16917-1
HDAC3 is highly expressed in brain, and its activity has been associated with negative regulation of learning and memory processes. RGFP966 is a selective inhibitor of HDAC3 (IC50 = 0.08 µM) that does not affect other HDACs at concentrations up to 15 µM. At 10 mg/kg, RGFP966 can facilitate the extinction of...
| Schlagworte: | (2E)-N-(2-amino-4-fluorophenyl)-3-[1-(3-phenyl-2-propen-1-yl)-1H-pyrazol-4-yl]-2-propenamide |
| Anwendung: | HDAC3 inhibitor |
| CAS | 1357389-11-7 |
| MW: | 362.4 D |
ab 49,00 €
Romidepsin
Artikelnummer: Cay17130-5
Romidepsin, also known as FK228, is a natural bicyclic depsipeptide that, following reduction, selectively inhibits class I histone deacetylases (HDACs). Reduction of a disulfide bond on romidepsin within the cell generates a zinc-binding thiol, allowing potent and selective inhibition of HDAC1, 2, 3, and 8 (IC50s =...
| Schlagworte: | FK228, FR901228, NSC 630176, cyclic... |
| Anwendung: | Class I HDAC inhibitor |
| CAS | 128517-07-7 |
| MW: | 540.7 D |
ab 169,00 €
HDAC3 Fluorogenic Assay kit
Artikelnummer: BPS-50073
The Fluorogenic HDAC3 Assay Kit is a complete assay system designed to measure HDAC3 activity for screening and profiling applications. It comes in a convenient 96-well format, with all the reagents necessary for 100 fluorescent HDAC3 activity measurements. In addition, the kit includes purified HDAC3 enzyme and the...
| Schlagworte: | HD3, HDAC3, RPD3-2, SMAP45, Histone deacetylase 3, Protein deacylase HDAC3, Protein deacetylase HDAC3, |
| Anwendung: | HDAC3 activity screening |
886,00 €
Anti-HDAC3
Artikelnummer: A300-464A
Protein function: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle...
| Schlagworte: | Anti-HD3, Anti-HDAC3, Anti-SMAP45, Anti-RPD3-2, EC=3.5.1.98, Anti-Histone deacetylase 3 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
HDAC3 Inhibitor
Artikelnummer: Cay21057-1
HDAC3 inhibitor is an allosteric inhibitor of histone deacetylase 3 (HDAC3, Ki = 0.16 nM). It is selective for HDAC3 over HDAC1 and HDAC2 (IC50s = 0.95, 11.81, and 95.45 nM, respectively, using recombinant HDACs). In addition, it is selective for acute myeloid, monocytic, and lymphoblastic leukemia cell lines (EC50s...
| Schlagworte: | Histone Deacetylase 3, 4-[[[(2E)-1-oxo-3-phenyl-2-propen-1-yl]amino]methyl]-benzoic acid 2-propylhydrazide |
| Anwendung: | Histone deacetylase 3 (HD3) inhibitor |
| CAS | 2044701-99-5 |
| MW: | 337.4 D |
ab 76,00 €