Zu "K11305" wurden 18 Artikel gefunden!
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WM-3835
Artikelnummer: Cay40296-10
WM-3835 is an inhibitor of lysine acetyltransferase 6A (KAT6A) and KAT7 (IC50s = 17 and 30 nM, respectively). It is selective for KAT6A and KAT7 over KAT5 (IC50 = 312 nM). WM-3835 (1 µM) reduces the viability of primary mouse leukemia stem cells (LSCs), MOLM-13 and OCI-AML-3 acute myeloid lymphoma (AML) cells, as...
| Schlagworte: | 4-fluoro-5-methyl-[1,1'-biphenyl]-3-carboxylic acid, 2-[(3-hydroxyphenyl)sulfonyl]hydrazide |
| Anwendung: | KAT6A / KAT7 inhibitor |
| CAS | 2229025-70-9 |
| MW: | 400.4 D |
ab 106,00 €
PF-9363
Artikelnummer: Cay37778-10
PF-9363 is an inhibitor of lysine acetyltransferase 6A (KAT6A), also known as monocytic leukemia zinc finger protein (MOZ) and KAT6B, also known as MOZ-related factor (MORF, Kis = 0.27 and 2.4 nM, respectively). It is selective for KAT6A and KAT6B over KAT7, KAT5, and KAT8 (Kis = 70, 420, and 670 nM, respectively)....
| Schlagworte: | CTx-648, 2,6-dimethoxy-N-[4-methoxy-6-(1H-pyrazol-1-ylmethyl)-1,2-benzisoxazol-3-yl]-benzenesulfonamide |
| Anwendung: | KAT6A / KAT6B inhibitor |
| CAS | 2569009-58-9 |
| MW: | 444.5 D |
ab 54,00 €
MOZ-IN-2
Artikelnummer: Cay27686-10
MOZ-IN-2 is an inhibitor of lysine acetyltransferase 6A (KAT6A/MOZ, IC50 = 125 µM).Formal Name: 2-(phenylsulfonyl)hydrazide 2-fluoro-5-(4-pyridazinyl)-benzoic acid. CAS Number: 2055397-88-9. Molecular Formula: C17H13FN4O3S. Formula Weight: 372.4. Purity: >98%. Formulation: (Request formulation change), A solid....
| Schlagworte: | 2-(phenylsulfonyl)hydrazide 2-fluoro-5-(4-pyridazinyl)-benzoic acid |
| Anwendung: | KAT6A/MOZ inhibitor |
| CAS | 2055397-88-9 |
| MW: | 372.4 D |
ab 39,00 €
WM-1119
Artikelnummer: Cay30509-5
WM-1119 is an orally bioavailable inhibitor of lysine acetyltransferase 6A (KAT6A/MOZ, IC50 = 6.3 nM). It binds to KAT6A with a Kd value of 2 nM and is selective for KAT6A over KAT5 and KAT7 (Kds = 2,200 and 500 nM, respectively), as well as over a panel of 159 additional targets at 1 and 10 µM. WM-1119 inhibits...
| Schlagworte: | 3-fluoro-5-(2-pyridinyl)-benzoic acid, 2-[(2-fluorophenyl)sulfonyl]hydrazide |
| Anwendung: | KAT6A inhibitor |
| CAS | 2055397-28-7 |
| MW: | 389.4 D |
ab 147,00 €
MOZ-IN-3
Artikelnummer: Cay27402-1
MOZ-IN-3 is an inhibitor of lysine acetyltransferase 6A (KAT6A/MOZ) and KAT6B/MORF (IC50s = 8 and 28 nM, respectively). It is selective for KAT6A and KAT6B over KAT5 and KAT7 (IC50s = 224 and 342 nM, respectively). MOZ-IN-3 induces cell cycle arrest in and inhibits proliferation of mouse embryonic fibroblasts (IC50...
| Schlagworte: | WM-8014, 4-fluoro-5-methyl-[1,1'-biphenyl]-3-carboxylic acid, 2-(phenylsulfonyl)hydrazide |
| Anwendung: | KAT6A/KAT6B inhibitor |
| CAS | 2055397-18-5 |
| MW: | 384.4 D |
ab 50,00 €
Anti-KAT6A
Artikelnummer: E-AB-66382.120
This gene encodes a member of the MOZ, YBFR2, SAS2, TIP60 family of histone acetyltransferases. The protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and...
| Schlagworte: | Anti-MOZ, Anti-KAT6A, Anti-MYST-3, Anti-Zinc finger protein 220, Anti-Histone acetyltransferase KAT6A, Anti-Monocytic... |
| Anwendung: | IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 198,00 €
Anti-KAT6A
Artikelnummer: G-CAB15006.100
WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:200. Protein function: Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2....
| Schlagworte: | Anti-MOZ, Anti-KAT6A, Anti-MYST-3, Anti-Zinc finger protein 220, Anti-Histone acetyltransferase KAT6A, Anti-Monocytic... |
| Anwendung: | WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 352,00 €
Anti-KAT6A
Artikelnummer: ATA-HPA063266.100
Protein function: Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2. Acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and...
| Schlagworte: | Anti-MOZ, Anti-KAT6A, Anti-MYST-3, Anti-Zinc finger protein 220, Anti-Histone acetyltransferase KAT6A, Anti-Monocytic... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 335,00 €
Anti-KAT6A
Artikelnummer: ATA-HPA065052.100
Protein function: Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2. Acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and...
| Schlagworte: | Anti-MOZ, Anti-KAT6A, Anti-MYST-3, Anti-Zinc finger protein 220, Anti-Histone acetyltransferase KAT6A, Anti-Monocytic... |
| Anwendung: | ICC, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 335,00 €
Anti-KAT6A
Artikelnummer: ELK-ES9214.100
This gene encodes a member of the MOZ, YBFR2, SAS2, TIP60 family of histone acetyltransferases. The protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and...
| Schlagworte: | Anti-MOZ, Anti-KAT6A, Anti-MYST-3, Anti-Zinc finger protein 220, Anti-Histone acetyltransferase KAT6A, Anti-Monocytic... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 169,00 €
MYST3, Human MYST histone acetyltransferase (monocytic...
Artikelnummer: VHPS-6017
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | MYST3, MYST3 protein |
| Anwendung: | RNA quantification |
43,00 €
Myst3, Rat MYST histone acetyltransferase (monocytic...
Artikelnummer: VRPS-3884
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | Moz, Myst3, MYST-3, EC=2.3.1.48, Histone acetyltransferase MYST3, Monocytic leukemia zinc finger homolog, Monocytic... |
| Anwendung: | RNA quantification |
52,00 €