Zu "K11256" wurden 31 Artikel gefunden!
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Cinobufotalin
Artikelnummer: TGM-T4A2399-10mg
Description: Cinobufotalin is a main cardiac toxin in toad, it is a novel anti-HCC agent, it induces growth inhibition and apoptosis in cultured HCC cells through ceramide production. Cinobufotalin is also an effective reversal agent for the multidrug resistance of tumors, it can reverse the adriamycin-resistance in...
| Anwendung: | Bioactive steroid glycoside |
| CAS | 1108-68-5 |
| MW: | 458.54 D |
ab 45,00 €
(E)-SI-2
Artikelnummer: TGM-T9836-100mg
Description: (E)-SI-2 is a potent small-molecule inhibitor of steroid receptor coactivator-3 (SRC-3 or AIB1) that can selectively inhibit the intrinsic transcriptional activities of SRC-3, also inhibits SRC-1 and SRC-2. It selectively reduces cellular protein levels of SRC-3, but not that of CARM-1, blocks...
| Anwendung: | SRC-3 / NCOA3 / AIB1 inhibitor |
| CAS | 380537-35-9 |
| MW: | 265.31 D |
ab 88,00 €
Bufalin
Artikelnummer: TGM-T1719-10mg
Description: Bufalin is an active ingredient and one of the glycosides in the traditional Chinese medicine ChanSu, it is also a bufadienolide toxin originally isolated from the venom of the Chinese toad Bufo gargarizans, with potential cardiotonic and antineoplastic activity. Although the mechanism of action of...
| Anwendung: | Na+/K+-ATPase transporter inhibitor, SRC-1/3 inhibitor |
| CAS | 465-21-4 |
| MW: | 386.52 D |
ab 55,00 €
Anti-NCOA3
Artikelnummer: CSB-PA005989.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-ACTR, Anti-AIB1, Anti-pCIP, Anti-NCOA3, Anti-SRC-3, Anti-AIB-1, Anti-RAC-3, Anti-NCoA-3, Anti-TRAM-1, Anti-bHLHe42,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
126,00 €
Anti-NCOA3
Artikelnummer: CSB-PA571370.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: NCOA3. Antigen Species: Human
| Schlagworte: | Anti-ACTR, Anti-AIB1, Anti-pCIP, Anti-NCOA3, Anti-SRC-3, Anti-AIB-1, Anti-RAC-3, Anti-NCoA-3, Anti-TRAM-1, Anti-bHLHe42,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
SI-2
Artikelnummer: Cay19565-25
SI-2 is an inhibitor of steroid receptor coactivator 3 (SRC-3). It has been shown to selectively reduce the transcriptional activities and the protein concentrations of SRC-3 in cells through direct physical interactions with SRC-3. SI-2 induces death in various breast cancer cells with IC50 values of 3-20 nM...
| Schlagworte: | EPH 116, (1E)-1-(2-pyridinyl)-ethanone-2-(1-methyl-1H-benzimidazol-2-yl)hydrazone |
| Anwendung: | SRC-3 / NCOA3 / AIB1 inhibitor |
| CAS | 380537-35-9 |
| MW: | 265.3 D |
ab 61,00 €
Bufalin
Artikelnummer: Cay15725-5
Bufalin is a cardiotonic steroid first isolated from toad venom and used in traditional Asian medicine. It inhibits the Na+/K+-ATPase transporter (Kds = 42, 45, and 40 nM for the alpha1, alpha2, and alpha3 subunits, respectively). Intravenously administered bufalin is cleared rapidly, with a plasma half-life of 25...
| Schlagworte: | NSC 89595, (3beta,5beta)-3,14-dihydroxy-bufa-20,22-dienolide |
| Anwendung: | Na+/K+-ATPase transporter inhibitor, SRC-1/3 inhibitor |
| CAS | 465-21-4 |
| MW: | 386.5 D |
ab 78,00 €
Anti-SRC3
Artikelnummer: A300-347A
Protein function: Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Plays a central role in creating a multisubunit coactivator complex, which probably acts via remodeling of chromatin. Involved in the coactivation of...
| Schlagworte: | Anti-AIB1, Anti-pCIP, Anti-ACTR, Anti-NCOA3, Anti-RAC-3, Anti-SRC-3, Anti-AIB-1, Anti-NCoA-3, Anti-TRAM-1, Anti-bHLHe42,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 178,00 €
Anti-SRC3
Artikelnummer: A300-348A
Protein function: Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Plays a central role in creating a multisubunit coactivator complex, which probably acts via remodeling of chromatin. Involved in the coactivation of...
| Schlagworte: | Anti-AIB1, Anti-pCIP, Anti-ACTR, Anti-NCOA3, Anti-RAC-3, Anti-SRC-3, Anti-AIB-1, Anti-NCoA-3, Anti-TRAM-1, Anti-bHLHe42,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 178,00 €
Anti-NCOA3
Artikelnummer: 600-401-A40
Protein function: Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Plays a central role in creating a multisubunit coactivator complex, which probably acts via remodeling of chromatin. Involved in the coactivation of...
| Schlagworte: | Anti-AIB1, Anti-pCIP, Anti-ACTR, Anti-AIB-1, Anti-SRC-3, Anti-RAC-3, Anti-NCOA3, Anti-TRAM-1, Anti-NCoA-3, Anti-bHLHe42,... |
| Anwendung: | ELISA, IHC, IP, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
719,00 €
Anti-NCOA3
Artikelnummer: 600-401-A40S
Protein function: Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Plays a central role in creating a multisubunit coactivator complex, which probably acts via remodeling of chromatin. Involved in the coactivation of...
| Schlagworte: | Anti-AIB1, Anti-pCIP, Anti-ACTR, Anti-AIB-1, Anti-SRC-3, Anti-RAC-3, Anti-NCOA3, Anti-TRAM-1, Anti-NCoA-3, Anti-bHLHe42,... |
| Anwendung: | ELISA, IHC, IP, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
180,00 €
Cinobufotalin
Artikelnummer: Cay19845-1
Cinobufotalin is a steroid glycoside originally isolated from the Asiatic toad (B. gargarizans) and has diverse biological activities. It reduces SRC-3 protein levels in MCF-7 breast cancer cells when used at concentrations ranging from 10 to 100 nM. Cinobufotalin (1 µM) reduces Na+/K+ pump activity, viability, and...
| Schlagworte: | NSC 90326, 16beta-(acetyloxy)-14,15beta-epoxy-3beta,5beta-dihydroxy-bufa-20,22-dienolide |
| Anwendung: | Bioactive steroid glycoside |
| CAS | 1108-68-5 |
| MW: | 458.6 D |
ab 49,00 €