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Zu "K11204" wurden 51 Artikel gefunden!
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Artikelnummer: Cay14484-250
L-Buthionine-(S,R)-sulfoximine is an irreversible inhibitor of gamma-glutamylcysteine synthetase (Ki = 25 µM). It inhibits the proliferation of ZAZ and M14 melanoma cells, as well as A2780 ovarian and MCF-7 breast cancer cells (IC50s = 4.9, 18, 8.5, and 26.5 µM, respectively). L-Buthionine-(S,R)-sulfoximine (100µM)...
| Schlagworte: | BSO, NSC 326231, 2S-amino-4-(S-butylsulfonimidoyl)-butanoic acid |
| Anwendung: | Oxidative stress inducer |
| CAS | 83730-53-4 |
| MW: | 222.3 D |
ab 127,00 €
Artikelnummer: NSJ-FY13385
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. GCLC antibody detects Glutamate-cysteine ligase catalytic subunit, a key enzyme encoded by the GCLC gene located on chromosome 6p12.1. GCLC catalyzes the first and rate-limiting step in glutathione (GSH) biosynthesis, forming...
| Schlagworte: | Anti-GCLC, Anti-Gamma-ECS, Anti-GCS heavy chain, Anti-Gamma-glutamylcysteine synthetase, Anti-Glutamate--cysteine ligase... |
| Anwendung: | ELISA, FC, IF, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Artikelnummer: E-PDEH101138.1
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from...
| Schlagworte: | GLCL, Gamma-ECS, GCS heavy chain, Gamma-glutamylcysteine synthetase, Glutamate--cysteine ligase catalytic subunit,... |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 47 kD |
ab 192,00 €
Artikelnummer: Cay23691-250
D,L-Buthionine-(S,R)-sulfoximine is an inhibitor of gamma-glutamylcysteine synthetase that induces 100% inhibition at a concentration of 10 µM in an enzyme assay. It is selective for gamma-glutamylcysteine synthetase, lacking activity at glutamine synthetase at concentrations up to 500 µM....
| Schlagworte: | NSC 381100, 2-amino-4-(S-butylsulfonimidoyl)-butanoic acid |
| Anwendung: | gamma-glutamylcysteine synthetase inhibitor |
| CAS | 5072-26-4 |
| MW: | 222.3 D |
ab 111,00 €
Artikelnummer: G-HUFI01282.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Artikelnummer: NSJ-R30565
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Glutamate--cysteine ligase catalytic subunit, is an enzyme that in humans is encoded by the GCLC gene. Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of...
| Schlagworte: | Anti-GCLC, Anti-GLCL, Anti-Gamma-ECS, EC=6.3.2.2, Anti-GCS heavy chain, Anti-Gamma-glutamylcysteine synthetase,... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Artikelnummer: NSJ-R31614
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Glutamate-cysteine ligase catalytic subunit is an enzyme that in humans is encoded by the GCLC gene. Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two...
| Schlagworte: | Anti-GLCL, Anti-GCLC, Anti-Gamma-ECS, EC=6.3.2.2, Anti-GCS heavy chain, Anti-Gamma-glutamylcysteine synthetase,... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
790,00 €
Artikelnummer: NSJ-F41799-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit,...
| Schlagworte: | Anti-GCLC, Anti-GLCL, Anti-Gamma-ECS, EC=6.3.2.2, Anti-GCS heavy chain, Anti-Gamma-glutamylcysteine synthetase,... |
| Anwendung: | WB, IHC, IF, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Artikelnummer: ARG58109.100
| Schlagworte: | Anti-GLCL, Anti-GCLC, Anti-Gamma-ECS, EC=6.3.2.2, Anti-GCS heavy chain, Anti-Gamma-glutamylcysteine synthetase,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse, rat |
707,00 €
Artikelnummer: NSJ-F46551-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit,...
| Schlagworte: | Anti-GCLC, Anti-GLCL, Anti-Gamma-ECS, EC=6.3.2.2, Anti-GCS heavy chain, Anti-Gamma-glutamylcysteine synthetase,... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 361,00 €
Artikelnummer: ARG58032.50
| Schlagworte: | Anti-GLCL, Anti-GCLC, Anti-Gamma-ECS, EC=6.3.2.2, Anti-GCS heavy chain, Anti-Gamma-glutamylcysteine synthetase,... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
559,00 €
Artikelnummer: E-AB-52359.120
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from...
| Schlagworte: | Anti-GCLC, Anti-GLCL, Anti-Gamma-ECS, EC=6.3.2.2, Anti-GCS heavy chain, Anti-Gamma-glutamylcysteine synthetase,... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €