Zu "K11160" wurden 17 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
PF-06424439
Artikelnummer: Cay17680-1
PF-06424439 is an orally bioavailable inhibitor of diacylglycerol acyltransferase 2 (DGAT-2, IC50 = 14 nM). It is selective for DGAT-2 over the related acyltransferases DGAT-1, MGAT-2, and MGAT-3 (IC50s = >50 µM). PF-06424439 (0.1-10 mg/kg) reduces plasma triglyceride levels in sucrose-fed rats in a dose-dependent...
| Schlagworte: | [(3R)-1-[2-[1-(4-chloro-1H-pyrazol-1-yl)cyclopropyl]-3H-imidazo[4,5-b]pyridin-5-yl]-3-piperidinyl]-1-pyrrolidinyl-methanon... |
| Anwendung: | DGAT2 inhibitor |
| CAS | 1469284-79-4 |
| MW: | 536 D |
ab 69,00 €
Anti-DGAT2, Internal
Artikelnummer: ARG64152.100
Protein function: Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides. Probably plays a central role in cytosolic lipid accumulation. In...
| Schlagworte: | Anti-ARAT, Anti-DGAT2, Anti-HMFN1045, EC=2.3.1.20, EC=2.3.1.76, Anti-Diglyceride acyltransferase 2, Anti-Retinol... |
| Anwendung: | ELISA, IHC (paraffin), WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Anti-DGAT2
Artikelnummer: NSJ-R34509-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Diacylglycerol O-acyltransferase-like protein 2 Protein function: Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using...
| Schlagworte: | Anti-ARAT, Anti-DGAT2, Anti-HMFN1045, EC=2.3.1.76, EC=2.3.1.20, Anti-Diglyceride acyltransferase 2, Anti-Retinol... |
| Anwendung: | WB, IHC, ELISA (peptide), EIA |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
Human DGAT2 (Diacylglycerol-O-Acyltransferase Homolog 2)...
Artikelnummer: ELK-ELK3251.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human DGAT2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human DGAT2. Next,...
| Schlagworte: | ARAT, HMFN1045, Diglyceride acyltransferase 2, Retinol O-fatty-acyltransferase, Diacylglycerol O-acyltransferase 2,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 374,00 €
PF-06424439 methanesulfonate
Artikelnummer: TGM-T12425-100mg
Description: PF-06424439 methanesulfonate, an orally administered, potent, and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM, demonstrates slow reversibility and time-dependent inhibition. It operates in a noncompetitive manner relative to the acyl-CoA substrate,...
| Anwendung: | DGAT2 inhibitor |
| CAS | 1469284-79-4 |
| MW: | 536.05 D |
ab 38,00 €
Ervogastat
Artikelnummer: TGM-T9186-100mg
Description: Ervogastat (PF-06865571) is a potent and well-tolerated diacylglycerol acyltransferase 2 inhibitor. Ervogastat reduces steatosis and hepatic triglyceride levels in non-alcoholic steatohepatitis (NASH). Target: Transferase. Smiles: O(C1=CC(C=2N=CC(C(N[C@H]3CCOC3)=O)=CN2)=CN=C1)C4=C(OCC)C=CC=N4....
| Schlagworte: | PF-06865571 |
| Anwendung: | DGAT-2 inhibitor |
| CAS | 2186700-33-2 |
| MW: | 407.42 D |
ab 124,00 €
Human DGAT2 (Diacylglycerol-O-Acyltransferase Homolog 2)...
Artikelnummer: G-AEKE07477.96
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human DGAT2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human DGAT2. Next,...
| Schlagworte: | DGAT2, Diglyceride acyltransferase 2, Diacylglycerol O-acyltransferase 2, Acyl-CoA retinol O-fatty-acyltransferase |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
694,00 €
Anti-DGAT2
Artikelnummer: ELK-ES9588.50
This gene encodes one of two enzymes which catalyzes the final reaction in the synthesis of triglycerides in which diacylglycerol is covalently bound to long chain fatty acyl-CoAs. The encoded protein catalyzes this reaction at low concentrations of magnesium chloride while the other enzyme has high activity at high...
| Schlagworte: | Anti-ARAT, Anti-HMFN1045, Anti-Diglyceride acyltransferase 2, Anti-Retinol O-fatty-acyltransferase, Anti-Diacylglycerol... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 173,00 €
Anti-DGAT2, NT (DGAT2, Diacylglycerol O-acyltransferase...
Artikelnummer: 034598.200
Acyl-CoA:diacylglycerol acyltransferase, or DGAT (EC 2.3.1.20), is responsible for the synthesis of triglycerides. It catalyzes a reaction in which diacylglycerol is covalently joined to long chain fatty acyl-CoAs. Applications: Suitable for use in Western Blot and ELISA. Other applications have not been tested. ,...
| Schlagworte: | Anti-ARAT, Anti-DGAT2, Anti-HMFN1045, EC=2.3.1.76, EC=2.3.1.20, Anti-Diglyceride acyltransferase 2, Anti-Retinol... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
865,00 €
Diacylglycerol-O-Acyltransferase Homolog 2 (DGAT2)...
Artikelnummer: 024655.96
Diacylglycerol-O-Acyltransferase Homolog 2 (DGAT2) BioAssay(TM) ELISA Kit (Human) is a sandwich enzyme immunoassay for the in vitro quantitative measurement of human DGAT2 in tissue homogenates and other biological fluids. Detection Range: 13.7-10,000pg/ml, Sensitivity: 7.1pg/ml, Storage and Stability: Desiccation...
| Schlagworte: | ARAT, DGAT2, HMFN1045, EC=2.3.1.76, EC=2.3.1.20, Diglyceride acyltransferase 2, Retinol O-fatty-acyltransferase,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
1.128,00 €
Rat DGAT2 (Diacylglycerol O-acyltransferase 2) ELISA Kit
Artikelnummer: G-AEFI00856.96
ELISA Type: Sandwich ELISA, Double Antibody. Detection Range: 31.25-2000µg/mL. Sensitivity: 18.75µg/mL. Sample Types: Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples. Protein function: Essential acyltransferase that catalyzes the terminal and only committed step in...
| Schlagworte: | ARAT, HMFN1045, Diglyceride acyltransferase 2, Retinol O-fatty-acyltransferase, Diacylglycerol O-acyltransferase 2,... |
| Anwendung: | Sandwich ELISA, Double Antibody |
| Spezies-Reaktivität: | rat |
698,00 €
DGAT2 (Vector pENTR223.1, Accession No. BC015234)
Artikelnummer: CSB-CL850407HU.10
Length: 1167 Sequence: atgaagaccc tcatagccgc ctactccggg gtcctgcgcg gcgagcgtca ggccgaggct gaccggagcc agcgctctca cggaggacct gcgctgtcgc gcgaggggtc tgggagatgg ggcactggat ccagcatcct ctccgccctc caggacctct tctctgtcac ctggctcaat aggtccaagg tggaaaagca gctacaggtc atctcagtgc tccagtgggt cctgtccttc cttgtactgg gagtggcctg...
| Schlagworte: | ARAT, HMFN1045, Diglyceride acyltransferase 2, Retinol O-fatty-acyltransferase, Diacylglycerol O-acyltransferase 2,... |
| Anwendung: | Molecular biology, clone |
| Spezies-Reaktivität: | human |
176,00 €