Zu "K11126" wurden 96 Artikel gefunden!
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NEU
360A (iodide)
Artikelnummer: Cay42501-10
360A is an inhibitor of telomerase (IC50 = 0. µM). It decreases the viability of in T98G glioma fibroblasts, CB193 astrocytoma and U-118 MG glioma cells, and primary human astrocytes (IC50s = 4. 3. 8. and 17. µM, respectively). 360A (5 µM) induces sister chromatid fusions and telomere loss in HeLa cervical cancer...
| Schlagworte: | 3,3'-[2,6-pyridinediylbis(carbonylimino)]bis[1-methyl-quinolinium, diiodide |
| Anwendung: | Telomerase inhibitor |
| CAS | 737763-37-0 |
| MW: | 703.3 D |
ab 259,00 €
Anti-Telomerase (hTERT Catalytic Unit)
Artikelnummer: 600-401-252
Protein function: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the...
| Schlagworte: | Anti-TP2, Anti-TERT, Anti-EST2, Anti-HEST2, EC=2.7.7.49, Anti-Telomerase catalytic subunit, Anti-Telomerase-associated... |
| Anwendung: | ELISA, IHC, IFM, IP, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 180,00 €
TERT Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-02186-100ug
Description: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the...
| Schlagworte: | HEST2, Telomerase-associated protein 2, Telomerase catalytic subunit, TERT, Telomerase reverse transcriptase |
| MW: | 22.7 kD |
ab 236,00 €
TRET Protein, Mouse, Recombinant (His & SUMO)
Artikelnummer: TGM-TMPH-02926-100ug
Description: TRET Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 54.1 kDa and the accession number is O70372.
| Schlagworte: | Tert, Telomerase reverse transcriptase, Telomerase catalytic subunit |
| MW: | 54.1 kD |
ab 359,00 €
6-Thio-2'-Deoxyguanosine
Artikelnummer: TGM-T6746-100mg
Description: 6-Thio-2'-Deoxyguanosine (beta-TGdR) is a nucleoside analog and telomerase substrate. Target: DNA/RNA Synthesis, Others. Smiles: Nc1nc(=S)c2ncn([C@H]3C[C@H](O)[C@@H](CO)O3)c2[nH]1. References: Mender I, et al. Cancer Discov. 2015, 5(1), 82-95.
| Schlagworte: | beta-TGdR, 6-Thio-dG |
| Anwendung: | Nucleoside analog, telomeric DNA damage inducer |
| CAS | 789-61-7 |
| MW: | 283.31 D |
ab 49,00 €
TMPyP4 tosylate
Artikelnummer: TGM-T13174-100mg
Description: TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and telomerase inhibitor that exhibits antitumor effects in osteosarcoma cell lines. Target: DNA/RNA Synthesis, Telomerase. Smiles:...
| Schlagworte: | TMP 1363 |
| Anwendung: | G-quadruplex stabilizer, telomerase inhibitor |
| CAS | 36951-72-1 |
| MW: | 1363.6 D |
ab 33,00 €
Cyclogalegenin
Artikelnummer: TGM-T3333-100mg
Description: Cyclogalegenin (Astramembrangenin) is able to elongate telomeres, resulting in increased lifespan of the animals. Target: Telomerase. Smiles: C[C@]12[C@]3([C@]4([C@]5(C4)[C@@]([C@@H](O)C3)(C(C)(C)[C@@H](O)CC5)[H])CC[C@]1(C)[C@]([C@@H](O)C2)([C@@]6(C)O[C@@H]([C@@](C)(C)O)CC6)[H])[H]. References: de Jesus...
| Schlagworte: | Cyclogalegigenin, Astramembrangenin, Cyclogalagenin, Cycloastragenol |
| Anwendung: | Reported telomerase activator |
| CAS | 84605-18-5 |
| MW: | 490.71 D |
ab 30,00 €
Costunolide
Artikelnummer: TGM-T2902-100mg
Description: Costunolide (Costus lactone) has anti-inflammatory and anti-oxidant properties and mediates apoptosis. Target: Endogenous Metabolite, Apoptosis, Telomerase. Smiles: [H][C@]12OC(=O)C(=C)[C@]1([H])CC\C(C)=C\CC\C(C)=C\2. References: Choi SH, et al, Cancer Lett, 2005, 227(2), 153-162.
| Schlagworte: | Costunolid, (+)-Costunolide, Costus lactone, NSC 106404 |
| Anwendung: | Apoptosis inducer |
| CAS | 553-21-9 |
| MW: | 232.32 D |
ab 49,00 €
beta-Rubromycin
Artikelnummer: TGM-T35428-1mg
Description: beta-Rubromycin is a bacterial metabolite originally isolated from Streptomyces that has diverse biological activities.1 It inhibits the growth of HMO2, KATO-III, and MCF-7 cells with GI50 values of 0.5, 0.84, and <0.1 µM, respectively. beta-rubromycin inhibits HIV-1 reverse transcriptase activity by...
| Anwendung: | Human telomerase inhibitor, HIV-1 reverse transcriptase inhibitor |
| CAS | 27267-70-5 |
| MW: | 536.445 D |
ab 214,00 €
MST-312
Artikelnummer: TGM-T41290-10mg
Description: MST-312 (Telomerase Inhibitor IX) is a derivative of green tea epigallocatechin gallate (EGCG). MST-312 is a telomerase inhibitor. MST-312 has research value in cancer, such as multiple myeloma (MM). Target: Telomerase. Smiles: Oc1cccc(C(=O)Nc2cccc(NC(=O)c3cccc(O)c3O)c2)c1O. References: Ameri Z, et al....
| Schlagworte: | Telomerase Inhibitor IX |
| Anwendung: | Telomerase inhibitor |
| CAS | 368449-04-1 |
| MW: | 380.35 D |
ab 31,00 €
RHPS4
Artikelnummer: TGM-T6967-100mg
Description: RHPS4 (RHPS 4 methosulfate) is a potent inhibitor of Telomerase at submicromolar. Target: Apoptosis, Telomerase. Smiles: COS([O-])(=O)=O.Cc1cc2n(C)c3ccc(F)cc3c3[n+](C)c4ccc(F)cc4c(c1)c23. References: Phatak P, et al. Br J Cancer. 2007, 96(8):1223-33.
| Schlagworte: | RHPS 4 methosulfate, NSC714187 |
| Anwendung: | Telomerase inhibitor |
| CAS | 390362-78-4 |
| MW: | 458.48 D |
ab 40,00 €
Anti-TERT
Artikelnummer: CSB-PA004257.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-TP2, Anti-TERT, Anti-EST2, Anti-HEST2, Anti-Telomerase catalytic subunit, Anti-Telomerase-associated protein 2,... |
| Anwendung: | ELISA, WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 126,00 €