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Anti-Telomerase (hTERT Catalytic Unit)
Anti-Telomerase (hTERT Catalytic Unit)

Artikelnummer: 600-401-252

Protein function: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the...
Schlagworte: Anti-TP2, Anti-TERT, Anti-EST2, Anti-HEST2, EC=2.7.7.49, Anti-Telomerase catalytic subunit, Anti-Telomerase-associated...
Anwendung: ELISA, IHC, IFM, IP, WB
Wirt: Rabbit
Spezies-Reaktivität: human
ab 180,00 €
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-10 %
Rabattaktion
Mouse TE (telomerase) ELISA Kit
Mouse TE (telomerase) ELISA Kit

Artikelnummer: ELK-ELK0407.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse TE. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse TE. Next,...
Schlagworte: Tert, EC=2.7.7.49, Telomerase catalytic subunit, Telomerase reverse transcriptase
Anwendung: ELISA
Spezies-Reaktivität: mouse
352,00 € ab 316,80 €
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-10 %
Rabattaktion
Human TERT (Telomerase Reverse Transcriptase) ELISA Kit
Human TERT (Telomerase Reverse Transcriptase) ELISA Kit

Artikelnummer: ELK-ELK3569.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human TERT. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TERT. Next,...
Schlagworte: TP2, TERT, EST2, HEST2, Telomerase catalytic subunit, Telomerase-associated protein 2, Telomerase reverse transcriptase
Anwendung: ELISA
Spezies-Reaktivität: human
365,00 € ab 328,50 €
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-10 %
Rabattaktion
Rat TERT (Telomerase Reverse Transcriptase) ELISA Kit
Rat TERT (Telomerase Reverse Transcriptase) ELISA Kit

Artikelnummer: ELK-ELK7049.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat TERT. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat TERT. Next,...
Schlagworte: EC=2.7.7.49, Telomerase catalytic subunit, Telomerase reverse transcriptase
Anwendung: ELISA
Spezies-Reaktivität: rat
365,00 € ab 328,50 €
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Costunolide
Costunolide

Artikelnummer: BPS-27745-2

Costunolide is a sesquiterpene lactone with anti-oxidant properties that is found in lettuce and other plants. It is widely used in many herbal medicines. Costunolide is a potent inducer of apoptosis, a potent anti-cancer agent, has anti-inflammatory, anti-viral, anti-fungal, antimycobacterial activity and has been...
Schlagworte: (+)-Costunolide, Costunolid, Costus lactone, NSC 106404,
Anwendung: Apoptosis inhibitor, anticancer agent
MW: 232.3 D
350,00 €
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Guanine-2'-deoxy-beta-L-ribofuranosyl-5'-O-triphosphate (sodium salt)
Guanine-2'-deoxy-beta-L-ribofuranosyl-5'-O-triphosphate...

Artikelnummer: Cay38465-2.5

Guanine-2'-deoxy-beta-L-ribofuranosyl-5'-O-triphosphate is an isomer of dGTP (Cay-35771) and an inhibitor of telomerase (Ki = 15 µM for the human enzyme).Formal Name: 2-amino-9-[2-deoxy-5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-beta-L-erythro-pentofuranosyl]-1,9-dihydro-6H-purin-6-one,...
Schlagworte: 2'-deoxy-L-GTP, L-2'-Deoxyguanosine 5'-triphosphate, beta-L-dGTP,...
Anwendung: dGTP isomer, telomerase inhibitor
MW: 595.1 D
477,00 €
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BIBR 1532
BIBR 1532

Artikelnummer: Cay16608-10

BIBR 1532 is a mixed-type non-competitive inhibitor of telomerase (IC50 = 93 nM) that has little effect on several mammalian DNA and RNA polymerases, bacterial DNA helicase, or HIV-1 reverse transcriptase. It specifically targets the telomerase reverse transcriptase catalytic subunit, TERT. Through its effects on...
Schlagworte: Telomerase Inhibitor X, 2-[[(2E)-3-(2-naphthalenyl)-1-oxo-2-buten-1-yl]amino]-benzoic acid
Anwendung: Telomerase / TERT inhibitor
CAS 321674-73-1
MW: 331.4 D
ab 43,00 €
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Gossypol-acetic acid
Gossypol-acetic acid

Artikelnummer: LKT-G5875.1

A potential male anti-fertility agent from cotton that exhibits a wide spectrum of toxicity. It was found to have cytotoxic effects on human cancer cell lines. It is a potent telomerase inhibitor.
Schlagworte: 1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1- methylethyl)(2,2'-binaphthalene)-8,8'-dicarboxaldehyde-acetic acid,...
Anwendung: Telomerase inhibitor
CAS 12542-36-8
MW: 578,61 D
ab 146,00 €
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-10 %
beta-Rubromycin
beta-Rubromycin

Artikelnummer: BVT-0251-M001

Antibiotic, HIV-1 reverse transcriptase inhibitor, Human telomerase inhibitor, Cytostatic against different tumor cell lines. Isolated from Streptomyces sp.
Schlagworte: Methyl-8,10'-dihydroxy-5,7-dimethoxy-4,9,9'-trioxo-4,4',9,9'-tetrahydro-3H,3'H-spiro[naphtho[2,3-b]furan-2,2'-pyrano[4,3-g...
Anwendung: Human telomerase inhibitor, HIV-1 reverse transcriptase inhibitor
CAS 27267-70-5
MW: 536,4 D
80,00 € ab 72,00 €
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TMPyP4 (tosylate)
TMPyP4 (tosylate)

Artikelnummer: Cay18474-50

TMPyP4 is a cationic porphyrin that intercalates into and stabilizes G-quadruplexes, which are formed by DNA and RNA sequences composed of blocks of guanine residues. In this way, TMPyP4 inhibits telomerase activity (IC50 = 50 µM), blocking the clonogenic growth and migration of cancer cells in culture and in vivo....
Schlagworte: TMP-1363, TMPyP4 4-methylbenzenesulfonate,...
Anwendung: G-quadruplex stabilizer, Telomerase inhibitor
CAS 36951-72-1
MW: 1363.6 D
ab 50,00 €
Bewerten
-10 %
gamma-Rubromycin
gamma-Rubromycin

Artikelnummer: BVT-0007-M001

Antibiotic, HIV-1 reverse transcriptase and human telomerase inhibitor, Antibacterial, Cytostatically active against different tumor cell lines. Isolated from Streptomyces sp.
Anwendung: Human telomerase inhibitor
CAS 27267-71-6
MW: 522,4 D
85,00 € ab 76,50 €
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Costunolide
Costunolide

Artikelnummer: Cay14743-1

Costunolide is a sesquiterpene lactone that is found naturally in certain plant extracts and in alternative medicine oils. It reduces growth (EC50 = 3-35 µM) and induces apoptosis in assorted cancer cell lines. Costunolide inhibits the activation of Akt (15 µM) in endometriotic epithelial cells and STAT3 activation...
Schlagworte: Costus lactone, Melampolide, NSC 106404, 3aS,4,5,8,9,11aR-hexahydro-6E,10E-dimethyl-3-methylene-cyclodeca[b]furan-2(3H)-one
Anwendung: Apoptosis inducer
CAS 553-21-9
MW: 232.3 D
ab 39,00 €
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