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Zu "K11126" wurden 66 Artikel gefunden!
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Artikelnummer: 600-401-252
Protein function: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the...
Schlagworte: | Anti-TP2, Anti-TERT, Anti-EST2, Anti-HEST2, EC=2.7.7.49, Anti-Telomerase catalytic subunit, Anti-Telomerase-associated... |
Anwendung: | ELISA, IHC, IFM, IP, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 180,00 €
-10 %
Rabattaktion
Artikelnummer: ELK-ELK0407.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse TE. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse TE. Next,...
Schlagworte: | Tert, EC=2.7.7.49, Telomerase catalytic subunit, Telomerase reverse transcriptase |
Anwendung: | ELISA |
Spezies-Reaktivität: | mouse |
352,00 €
ab 316,80 €
-10 %
Rabattaktion
Artikelnummer: ELK-ELK3569.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human TERT. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TERT. Next,...
Schlagworte: | TP2, TERT, EST2, HEST2, Telomerase catalytic subunit, Telomerase-associated protein 2, Telomerase reverse transcriptase |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
365,00 €
ab 328,50 €
-10 %
Rabattaktion
Artikelnummer: ELK-ELK7049.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat TERT. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat TERT. Next,...
Schlagworte: | EC=2.7.7.49, Telomerase catalytic subunit, Telomerase reverse transcriptase |
Anwendung: | ELISA |
Spezies-Reaktivität: | rat |
365,00 €
ab 328,50 €
Artikelnummer: BPS-27745-2
Costunolide is a sesquiterpene lactone with anti-oxidant properties that is found in lettuce and other plants. It is widely used in many herbal medicines. Costunolide is a potent inducer of apoptosis, a potent anti-cancer agent, has anti-inflammatory, anti-viral, anti-fungal, antimycobacterial activity and has been...
Schlagworte: | (+)-Costunolide, Costunolid, Costus lactone, NSC 106404, |
Anwendung: | Apoptosis inhibitor, anticancer agent |
MW: | 232.3 D |
350,00 €
Artikelnummer: Cay38465-2.5
Guanine-2'-deoxy-beta-L-ribofuranosyl-5'-O-triphosphate is an isomer of dGTP (Cay-35771) and an inhibitor of telomerase (Ki = 15 µM for the human enzyme).Formal Name: 2-amino-9-[2-deoxy-5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-beta-L-erythro-pentofuranosyl]-1,9-dihydro-6H-purin-6-one,...
Schlagworte: | 2'-deoxy-L-GTP, L-2'-Deoxyguanosine 5'-triphosphate, beta-L-dGTP,... |
Anwendung: | dGTP isomer, telomerase inhibitor |
MW: | 595.1 D |
477,00 €
Artikelnummer: Cay16608-10
BIBR 1532 is a mixed-type non-competitive inhibitor of telomerase (IC50 = 93 nM) that has little effect on several mammalian DNA and RNA polymerases, bacterial DNA helicase, or HIV-1 reverse transcriptase. It specifically targets the telomerase reverse transcriptase catalytic subunit, TERT. Through its effects on...
Schlagworte: | Telomerase Inhibitor X, 2-[[(2E)-3-(2-naphthalenyl)-1-oxo-2-buten-1-yl]amino]-benzoic acid |
Anwendung: | Telomerase / TERT inhibitor |
CAS | 321674-73-1 |
MW: | 331.4 D |
ab 43,00 €
Artikelnummer: LKT-G5875.1
A potential male anti-fertility agent from cotton that exhibits a wide spectrum of toxicity. It was found to have cytotoxic effects on human cancer cell lines. It is a potent telomerase inhibitor.
Schlagworte: | 1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1- methylethyl)(2,2'-binaphthalene)-8,8'-dicarboxaldehyde-acetic acid,... |
Anwendung: | Telomerase inhibitor |
CAS | 12542-36-8 |
MW: | 578,61 D |
ab 146,00 €
-10 %
Artikelnummer: BVT-0251-M001
Antibiotic, HIV-1 reverse transcriptase inhibitor, Human telomerase inhibitor, Cytostatic against different tumor cell lines. Isolated from Streptomyces sp.
Schlagworte: | Methyl-8,10'-dihydroxy-5,7-dimethoxy-4,9,9'-trioxo-4,4',9,9'-tetrahydro-3H,3'H-spiro[naphtho[2,3-b]furan-2,2'-pyrano[4,3-g... |
Anwendung: | Human telomerase inhibitor, HIV-1 reverse transcriptase inhibitor |
CAS | 27267-70-5 |
MW: | 536,4 D |
80,00 €
ab 72,00 €
Artikelnummer: Cay18474-50
TMPyP4 is a cationic porphyrin that intercalates into and stabilizes G-quadruplexes, which are formed by DNA and RNA sequences composed of blocks of guanine residues. In this way, TMPyP4 inhibits telomerase activity (IC50 = 50 µM), blocking the clonogenic growth and migration of cancer cells in culture and in vivo....
Schlagworte: | TMP-1363, TMPyP4 4-methylbenzenesulfonate,... |
Anwendung: | G-quadruplex stabilizer, Telomerase inhibitor |
CAS | 36951-72-1 |
MW: | 1363.6 D |
ab 50,00 €
-10 %
Artikelnummer: BVT-0007-M001
Antibiotic, HIV-1 reverse transcriptase and human telomerase inhibitor, Antibacterial, Cytostatically active against different tumor cell lines. Isolated from Streptomyces sp.
Anwendung: | Human telomerase inhibitor |
CAS | 27267-71-6 |
MW: | 522,4 D |
85,00 €
ab 76,50 €
Artikelnummer: Cay14743-1
Costunolide is a sesquiterpene lactone that is found naturally in certain plant extracts and in alternative medicine oils. It reduces growth (EC50 = 3-35 µM) and induces apoptosis in assorted cancer cell lines. Costunolide inhibits the activation of Akt (15 µM) in endometriotic epithelial cells and STAT3 activation...
Schlagworte: | Costus lactone, Melampolide, NSC 106404, 3aS,4,5,8,9,11aR-hexahydro-6E,10E-dimethyl-3-methylene-cyclodeca[b]furan-2(3H)-one |
Anwendung: | Apoptosis inducer |
CAS | 553-21-9 |
MW: | 232.3 D |
ab 39,00 €