Zu "K11121" wurden 16 Artikel gefunden!
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Splitomycin
Artikelnummer: AG-CR1-0088-M001
Potent cell permeable and selective inhibitor of yeast NAD-dependent histone deacetylase (HDAC) Sir2p. Displays higher activity in vivo than in vitro. Sensitizes mammalian cells to a variety of DNA-damaging agents by abrogating Sir2p activity on p53. Acts by either altering or blocking access to the acetylated...
| Schlagworte: | 1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one, 1-Naphthalen propanoic acid |
| Anwendung: | HDAC inhibitor |
| CAS | 5690-03-9 |
| MW: | 198,2 D |
ab 33,00 €
Splitomicin
Artikelnummer: Cay13168-10
Sir2p, the product of the SIR2 gene, is a conserved NAD+-dependent histone deacetylase (HDAC) involved in the regulation of the lifespan in yeast. It plays roles in silencing gene expression and negatively regulates the initiation of DNA replication. Splitomicin is a small molecule inhibitor of Sir2p histone...
| Schlagworte: | 1-Naphthalenepropanoic Acid, 1,2-dihydro-3H-naphtho[2,1-b]pyran-3-one |
| Anwendung: | SIR2p inhibitor |
| CAS | 5690-03-9 |
| MW: | 198.2 D |
ab 51,00 €
Splitomicin
Artikelnummer: LKT-S6247.10
Splitomicin is a cell-permeable lactone that acts as an inhibitor of sirtuins 1 and 2 (SIRT1, SIRT2), sirtuins are considered class III histone deacetylases (HDACs). Splitomicin displays anti-inflammatory, antioxidative, and antithrombotic activities. In vitro, splitomicin promotes translocation of FOXO3a,...
| Anwendung: | SIRT1 / SIRT2 inhibitor |
| CAS | 5690-03-9 |
| MW: | 198.22 D |
ab 94,00 €
Splitomicin
Artikelnummer: TGM-T6678-5mg
Description: Splitomicin (1-Naphthalenepropanoic Acid) (IC50 of 60 µM), a specific inhibitor of NAD(+)-dependent histone deacetylase Sir2p, displays a high activity in a cell-based assay. Target: Sirtuin, HDAC. Smiles: O=C1CCc2c(O1)ccc1ccccc21. References: Bedalov A, et al. Proc Natl Acad Sci U S A. 2001, 98(26),...
| Schlagworte: | 1-Naphthalenepropanoic Acid |
| Anwendung: | HDAC inhibitor |
| CAS | 5690-03-9 |
| MW: | 198.22 D |
39,00 €
NEU
Anti-SIR2
Artikelnummer: CSB-PA758736XA01DOT.100
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Schlagworte: | Anti-SIR2, Anti-AEL013C, Anti-Regulatory protein SIR2, Anti-Silent information regulator 2, Anti-NAD-dependent histone... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) |
1.529,00 €
Anti-HST4
Artikelnummer: CSB-PA345310XA01SVG.100
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Schlagworte: | Anti-HST4, Anti-YDR191W, Anti-YD9346.03, Anti-Homologous to SIR2 protein 4, Anti-Regulatory protein SIR2 homolog 4,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
ab 1.529,00 €
Anti-HST2
Artikelnummer: CSB-PA345697XA01SVG.100
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Schlagworte: | Anti-HST2, Anti-LPA2C, Anti-YPL015C, Anti-Homologous to SIR2 protein 2, Anti-Regulatory protein SIR2 homolog 2,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
ab 1.529,00 €
Anti-HST1
Artikelnummer: CSB-PA346102XA01SVG.100
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Schlagworte: | Anti-HST1, Anti-YOL068C, Anti-Homologous to SIR2 protein 1, Anti-Regulatory protein SIR2 homolog 1, Anti-NAD-dependent... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
ab 1.529,00 €
Anti-SIR2
Artikelnummer: CSB-PA361922XA01SVG.100
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Schlagworte: | Anti-SIR2, Anti-MAR1, Anti-D2714, Anti-YDL042C, Anti-Regulatory protein SIR2, Anti-Silent information regulator 2,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
ab 1.529,00 €
Anti-HST3
Artikelnummer: CSB-PA346476XA01SVG.100
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Schlagworte: | Anti-HST3, Anti-YOR025W, Anti-OR26.15, Anti-Homologous to SIR2 protein 3, Anti-Regulatory protein SIR2 homolog 3,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
ab 1.529,00 €
Anti-sir2
Artikelnummer: CSB-PA528484XA01SXV.100
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Schlagworte: | Anti-sir2, Anti-SPBC16D10.07c, Anti-Regulatory protein sir2, Anti-Silent information regulator 2, Anti-NAD-dependent... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
ab 1.529,00 €