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Human NKCC1 (Na-K-Cl Cotransporter 1) ELISA Kit
Human NKCC1 (Na-K-Cl Cotransporter 1) ELISA Kit

Artikelnummer: ELK-ELK0483.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human NKCC1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human NKCC1. Next,...
Schlagworte: SLC12A2, Basolateral Na-K-Cl symporter, Solute carrier family 12 member 2, Bumetanide-sensitive...
Anwendung: ELISA
Spezies-Reaktivität: human
ab 365,00 €
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Furosemide
Furosemide

Artikelnummer: Cay26298-5

Furosemide (Cay-26298) is an analytical reference standard categorized as a diuretic. Formulations containing diuretics, including furosemide, have been misused in sports for weight reduction and as masking agents in humans and to prevent exercise-induced pulmonary hemorrhage in racehorses. This product is intended...
Schlagworte: Frusemide, NSC 269420, 5-(aminosulfonyl)-4-chloro-2-[(2-furanylmethyl)amino]-benzoic acid
Anwendung: Analytical reference standard, Diuretic, Na-K-Cl cotransporter inhibitor
CAS 54-31-9
MW: 330.7 D
ab 60,00 €
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Ethacrynic Acid
Ethacrynic Acid

Artikelnummer: Cay26299-50

Ethacrynic acid (Cay-26299) is an analytical reference standard categorized as a loop diuretic. Diuretics, including ethacrynic acid, have been used as masking agents in sports doping, including racehorse doping. This product is intended for use in analytical forensic applications. This product is also available as...
Schlagworte: MK-595, NSC 624008, NSC 85791, 2-[2,3-dichloro-4-(2-methylene-1-oxobutyl)phenoxy]-acetic acid
Anwendung: Analytical reference standard, Loop diuretic, Na-K-Cl cotransporter inhibitor
CAS 58-54-8
MW: 303.1 D
ab 60,00 €
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Anti-NKCC1 / SLC12A2, clone 6G7D2
Anti-NKCC1 / SLC12A2, clone 6G7D2

Artikelnummer: NSJ-RQ7382

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Solute carrier family 12 (sodium/potassium/chloride transporters), member 2, also known as NKCC1, is widely distributed throughout the body, especially in organs that secrete fluids, called exocrine glands. By fluorescence in situ hybridization, this gene is...
Schlagworte: Anti-SLC12A2, Anti-Basolateral Na-K-Cl symporter, Anti-Solute carrier family 12 member 2, Anti-Bumetanide-sensitive...
Anwendung: WB, IHC (paraffin)
Wirt: Mouse
Spezies-Reaktivität: human, mouse, rat
755,00 €
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Bumetanide
Bumetanide

Artikelnummer: Cay14630-1

Bumetanide is an inhibitor of Na-K-2Cl cotransporter 1 (NKCC1, IC50 = 0.68 µM). It is selective for NKCC1 over NKCC2 (IC50 = 4 µM). Bumetanide is an agonist of G protein-coupled receptor 35 (GPR35, EC50 = 10 µM). It also inhibits various carbonic anhydrases. Bumetanide (0.1 mg/kg) increases urine flow and sodium and...
Schlagworte: PF 1593, Ro 10-6338, 3-(aminosulfonyl)-5-(butylamino)-4-phenoxy-benzoic acid
Anwendung: NKCC1/2 inhibitor
CAS 28395-03-1
MW: 364.4 D
ab 60,00 €
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Furosemide-d5
Furosemide-d5

Artikelnummer: Cay31789-1

Furosemide-d5 is intended for use as an internal standard for the quantification of furosemide (Cay-17273) by GC- or LC-MS. Furosemide is a loop diuretic and an inhibitor of the Na+/K+/2Cl- (NKCC) cotransporters, NKCC1 and NKCC2 (Kis = ~10 µM for both). In vivo, furosemide (0.1 mg/kg, p.o.) increases diuresis in...
Schlagworte: Frusemide-d5, 4-chloro-2-(((furan-2-yl-d3)methyl-d2)amino)-5-sulfamoylbenzoic acid
Anwendung: GC-MS, LC-MS, quantification, internal standard, NKCC inhibitor
CAS 1189482-35-6
MW: 335.8 D
442,00 €
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Bumetanide
Bumetanide

Artikelnummer: LKT-B8248.250

Bumetanide binds to Na-K-Cl co-transporter and inhibits its action.
Anwendung: Metabolic studies
CAS 28395-03-1
MW: 364,42 D
ab 149,00 €
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Furosemide
Furosemide

Artikelnummer: Cay17273-1

Furosemide is a loop diuretic and an inhibitor of the Na+/K+/2Cl- (NKCC) cotransporters, NKCC1 and NKCC2 (Kis = ~10 µM for both). In vivo, furosemide (0.1 mg/kg, p.o.) increases diuresis in beagle dogs. Furosemide (30 mg/kg) reduces ventricular collagen deposition and fibrosis in a rat model of dilated...
Schlagworte: Frusemide, 5-(aminosulfonyl)-4-chloro-2-[(2-furanylmethyl)amino]-benzoic acid
Anwendung: NKCC inhibitor
CAS 54-31-9
MW: 330.7 D
ab 43,00 €
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Bumetanide-d5
Bumetanide-d5

Artikelnummer: Cay26773-500

Bumetanide-d5 is intended for use as an internal standard for the quantification of bumetanide (Cay-14630) by GC- or LC-MS. Bumetanide is an inhibitor of Na-K-2Cl cotransporter 1 (NKCC1, IC50 = 0.68 µM). It is selective for NKCC1 over NKCC2 (IC50 = 4 µM). Bumetanide is an agonist of G protein-coupled receptor 35...
Schlagworte: 3-(aminosulfonyl)-5-(butylamino)-4-phenoxy-d5-benzoic acid
Anwendung: GC-MS, LC-MS, Quantification, Internal standard, Na-K-Cl cotransporter inhibitor
CAS 1216739-35-3
MW: 369.4 D
ab 147,00 €
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Torasemide-d7
Torasemide-d7

Artikelnummer: Cay26790-500

Torasemide-d7 is intended for use as an internal standard for the quantification of torasemide by GC- or LC-MS. Torasemide is a loop diuretic. In vivo, torasemide (6 mg/kg) increases fractional potassium, sodium, and chloride excretion and increases urine flow in rats. Formulations containing torsemide have been...
Schlagworte: Torsemide-d7, N-[[(1-methylethyl-d7)amino]carbonyl]-4-[(3-methylphenyl)amino]-3-pyridinesulfonamide
Anwendung: GC-MS, LC-MS, Quantification, Internal standard, Diuretic, Na-K-Cl cotransporter inhibitor
CAS 1189375-06-1
MW: 355.5 D
ab 125,00 €
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Bumetanide
Bumetanide

Artikelnummer: AG-CR1-3543-G005

Bumetanide is a loop diuretic that is clinically used to treat congestive heart failure. Bumetanide also exhibits anxiolytic, neuroprotective and anti-epileptic/anticonvulsant activities. Bumetanide induces hyperpolarization in kidney cells, increasing whole-cell conductance and intracellular Ca2+ levels. Bumetanide...
Schlagworte: PF-1593, Ro 10-6338, 3-(Aminosulfonyl)-5-(butylamino)-4-phenoxybenzoic acid
Anwendung: Na-K-Cl cotransporter inhibitor
CAS 28395-03-1
MW: 364,4 D
ab 33,00 €
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Anti-SLC12A2, Internal
Anti-SLC12A2, Internal

Artikelnummer: ARG65201.100

Protein function: Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume. [The UniProt Consortium]
Schlagworte: Anti-NKCC1, Anti-SLC12A2, Anti-Basolateral Na-K-Cl symporter, Anti-Solute carrier family 12 member 2,...
Anwendung: ELISA, IHC (paraffin)
Wirt: Goat
Spezies-Reaktivität: human
784,00 €
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