Zu "K10951" wurden 45 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
Furosemide-d5
Artikelnummer: Cay31789-1
Furosemide-d5 is intended for use as an internal standard for the quantification of furosemide (Cay-17273) by GC- or LC-MS. Furosemide is a loop diuretic and an inhibitor of the Na+/K+/2Cl- (NKCC) cotransporters, NKCC1 and NKCC2 (Kis = ~10 µM for both). In vivo, furosemide (0.1 mg/kg, p.o.) increases diuresis in...
| Schlagworte: | Frusemide-d5, 4-chloro-2-(((furan-2-yl-d3)methyl-d2)amino)-5-sulfamoylbenzoic acid |
| Anwendung: | GC-MS, LC-MS, quantification, internal standard, NKCC inhibitor |
| CAS | 1189482-35-6 |
| MW: | 335.8 D |
489,00 €
Bumetanide
Artikelnummer: Cay14630-1
Bumetanide is an inhibitor of Na-K-2Cl cotransporter 1 (NKCC1, IC50 = 0.68 µM). It is selective for NKCC1 over NKCC2 (IC50 = 4 µM). Bumetanide is an agonist of G protein-coupled receptor 35 (GPR35, EC50 = 10 µM). It also inhibits various carbonic anhydrases. Bumetanide (0.1 mg/kg) increases urine flow and sodium and...
| Schlagworte: | PF 1593, Ro 10-6338, 3-(aminosulfonyl)-5-(butylamino)-4-phenoxy-benzoic acid |
| Anwendung: | NKCC1/2 inhibitor |
| CAS | 28395-03-1 |
| MW: | 364.4 D |
ab 67,00 €
Bumetanide
Artikelnummer: LKT-B8248.250
Bumetanide binds to Na-K-Cl co-transporter and inhibits its action.
| Anwendung: | Metabolic studies |
| CAS | 28395-03-1 |
| MW: | 364,42 D |
ab 157,00 €
Torasemide-d7
Artikelnummer: Cay26790-500
Torasemide-d7 is intended for use as an internal standard for the quantification of torasemide by GC- or LC-MS. Torasemide is a loop diuretic. In vivo, torasemide (6 mg/kg) increases fractional potassium, sodium, and chloride excretion and increases urine flow in rats. Formulations containing torsemide have been...
| Schlagworte: | Torsemide-d7, N-[[(1-methylethyl-d7)amino]carbonyl]-4-[(3-methylphenyl)amino]-3-pyridinesulfonamide |
| Anwendung: | GC-MS, LC-MS, quantification, internal standard, diuretic, Na-K-Cl cotransporter inhibitor |
| CAS | 1189375-06-1 |
| MW: | 355.5 D |
ab 139,00 €
Furosemide
Artikelnummer: Cay17273-1
Furosemide is a loop diuretic and an inhibitor of the Na+/K+/2Cl- (NKCC) cotransporters, NKCC1 and NKCC2 (Kis = ~10 µM for both). In vivo, furosemide (0.1 mg/kg, p.o.) increases diuresis in beagle dogs. Furosemide (30 mg/kg) reduces ventricular collagen deposition and fibrosis in a rat model of dilated...
| Schlagworte: | Frusemide, 5-(aminosulfonyl)-4-chloro-2-[(2-furanylmethyl)amino]-benzoic acid |
| Anwendung: | NKCC inhibitor |
| CAS | 54-31-9 |
| MW: | 330.7 D |
ab 49,00 €
Bumetanide-d5
Artikelnummer: Cay26773-500
Bumetanide-d5 is intended for use as an internal standard for the quantification of bumetanide (Cay-14630) by GC- or LC-MS. Bumetanide is an inhibitor of Na-K-2Cl cotransporter 1 (NKCC1, IC50 = 0.68 µM). It is selective for NKCC1 over NKCC2 (IC50 = 4 µM). Bumetanide is an agonist of G protein-coupled receptor 35...
| Schlagworte: | 3-(aminosulfonyl)-5-(butylamino)-4-phenoxy-d5-benzoic acid |
| Anwendung: | GC-MS, LC-MS, quantification, internal standard, Na-K-Cl cotransporter inhibitor |
| CAS | 1216739-35-3 |
| MW: | 369.4 D |
ab 163,00 €
Bumetanide
Artikelnummer: AG-CR1-3543-G005
Bumetanide is a loop diuretic that is clinically used to treat congestive heart failure. Bumetanide also exhibits anxiolytic, neuroprotective and anti-epileptic/anticonvulsant activities. Bumetanide induces hyperpolarization in kidney cells, increasing whole-cell conductance and intracellular Ca2+ levels. Bumetanide...
| Schlagworte: | PF-1593, Ro 10-6338, 3-(Aminosulfonyl)-5-(butylamino)-4-phenoxybenzoic acid |
| Anwendung: | Na-K-Cl cotransporter inhibitor |
| CAS | 28395-03-1 |
| MW: | 364,4 D |
ab 33,00 €
Anti-SLC12A2, Internal
Artikelnummer: ARG65201.100
Protein function: Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume. [The UniProt Consortium]
| Schlagworte: | Anti-NKCC1, Anti-SLC12A2, Anti-Basolateral Na-K-Cl symporter, Anti-Solute carrier family 12 member 2,... |
| Anwendung: | ELISA, IHC (paraffin) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Anti-NKCC1 SLC12A2
Artikelnummer: NSJ-R31290
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Solute carrier family 12 (sodium/potassium/chloride transporters), member 2, also known as NKCC1 (Na-K-Cl Cotransporter 1), is widely distributed throughout the body, especially in organs that secrete fluids, called exocrine glands. By fluorescence in situ...
| Schlagworte: | Anti-BSC2, Anti-hNKCC1, Anti-SLC12A2, Anti-Na-K-2Cl cotransporter 1, Anti-Basolateral Na-K-Cl symporter, Anti-Solute... |
| Anwendung: | WB, IHC (paraffin), IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-SLC12A2
Artikelnummer: NSJ-R34763-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Solute carrier family 12 (sodium/potassium/chloride transporters), member 2 Protein function: Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital...
| Schlagworte: | Anti-NKCC1, Anti-SLC12A2, Anti-Basolateral Na-K-Cl symporter, Anti-Solute carrier family 12 member 2,... |
| Anwendung: | IHC, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
Anti-SLC12A2
Artikelnummer: ATA-HPA020130.100
Protein function: Cation-chloride cotransporter which mediates the electroneutral transport of chloride, potassium and/or sodium ions across the membrane. Plays a vital role in the regulation of ionic balance and cell volume. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added...
| Schlagworte: | Anti-NKCC1, Anti-SLC12A2, Anti-Basolateral Na-K-Cl symporter, Anti-Solute carrier family 12 member 2,... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
Anti-SLC12A2
Artikelnummer: ATA-HPA063697.100
Protein function: Cation-chloride cotransporter which mediates the electroneutral transport of chloride, potassium and/or sodium ions across the membrane. Plays a vital role in the regulation of ionic balance and cell volume. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added...
| Schlagworte: | Anti-NKCC1, Anti-SLC12A2, Anti-Basolateral Na-K-Cl symporter, Anti-Solute carrier family 12 member 2,... |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €