Zu "K10900" wurden 59 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
WRN Protein, Human, Recombinant (aa 500-946, His & MBP)
Artikelnummer: TGM-TMPH-03817-100ug
Description: WRN Protein, Human, Recombinant (aa 500-946, His & MBP) is expressed in E. coli with N-MBP, C-6xHis. The accession number is Q14191.
| Schlagworte: | RECQL2 , WRN , Werner syndrome protein , RecQ protein-like 2 , Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN ,... |
| MW: | 94.6 kD |
ab 93,00 €
GSK_WRN4
Artikelnummer: Cay45316-1
A covalent inhibitor of WRN (IC50 = 25 nM), inhibits tumor growth and increases the intratumoral levels of the DNA damage markers p21, phosphorylated gammaH2AX, and phosphorylated KAP-1 in an SW48 mouse xenograft model at 300 mg/kg. SMILES: O=S(C=C[C@H]1NC(C2=CC=C(NC2=O)C3CCCCC3)=O)(C1)=O. InChi Code:...
| Schlagworte: | 6-cyclohexyl-N-[(3R)-2,3-dihydro-1,1-dioxido-3-thienyl]-1,2-dihydro-2-oxo-3-pyridinecarboxamide |
| Anwendung: | Covalent WRN (RECQL2/RECQ3) inhibitor |
| CAS | 2923008-66-4 |
| MW: | 336.41 D |
ab 730,00 €
WRN Inhibitor 8
Artikelnummer: Cay43724-1
WRN inhibitor 8 is an inhibitor of the DNA helicase Werner syndrome protein (WRN, IC50 = 48.3 nM). It inhibits the growth of HCT116 and SW480 colorectal cancer cells (GI50s = 0.01699 and 13.64 µM, respectively). SMILES FC(F)(C1CC1)C2=NC=C(C(OC3=CC=CC=C3)=N2)C(N[C@H](/C=C/S(=O)(C)=O)C4CC4)=O InChi Code...
| Schlagworte: | 2-(cyclopropyldifluoromethyl)-N-[(1S,2E)-1-cyclopropyl-3-(methylsulfonyl)-2-propen-1-yl]-4-phenoxy-5-pyrimidinecarboxamide |
| Anwendung: | WRN inhibitor |
| CAS | 3026502-95-1 |
| MW: | 463.5 D |
ab 223,00 €
Anti-WRN
Artikelnummer: A300-238A
The protein product of the Werners syndrome (WRN) gene is the Werner syndrome ATP-dependent helicase. WRN is part of the ReqQ family of helicases that unwind DNA in preparation for replication, transcription, and repair. WRN appears to play a versatile role in cellular processes including DNA replication,...
| Schlagworte: | Anti-Werner syndrome protein variant |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-WRN (IHC)
Artikelnummer: IHC-00407-T
The protein product of the Werners syndrome (WRN) gene is the Werner syndrome ATP-dependent helicase. WRN is part of the ReqQ family of helicases that unwind DNA in preparation for replication, transcription, and repair. WRN appears to play a versatile role in cellular processes including DNA replication,...
| Schlagworte: | Anti-Werner syndrome protein variant |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
NSC 617145
Artikelnummer: Cay21973-1
NSC 617145 is an inhibitor of WRN helicase (IC50 = 230 nM) that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependent manner. It is selective for WRN over BLM, FANCJ, ChlR1, RecQ, and UvrD helicases, only exhibiting 7% inhibition of RECQ1 at a concentration of 5 µM. NSC...
| Schlagworte: | 1,1'-(2,2-dimethyl-1,3-propanediyl)bis[3,4-dichloro-1H-pyrrole-2,5-dione |
| Anwendung: | WRN inhibitor |
| CAS | 203115-63-3 |
| MW: | 400 D |
ab 54,00 €
Anti-WRN
Artikelnummer: A300-239A
The protein product of the Werners syndrome (WRN) gene is the Werner syndrome ATP-dependent helicase. WRN is part of the ReqQ family of helicases that unwind DNA in preparation for replication, transcription, and repair. WRN appears to play a versatile role in cellular processes including DNA replication,...
| Schlagworte: | Anti-Werner syndrome protein variant |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
586,00 €
Anti-WRN
Artikelnummer: ARG59158.100
Protein function: Multifunctional enzyme that has both magnesium and ATP- dependent DNA-helicase activity and 3'->5' exonuclease activity towards double-stranded DNA with a 5'-overhang. Has no nuclease activity towards single-stranded DNA or blunt-ended double- stranded DNA. Binds preferentially to DNA substrates...
| Schlagworte: | Anti-WRN, Anti-RECQ3, Anti-RecQ3, EC=3.1.-.-, Anti-Exonuclease WRN, Anti-RecQ protein-like 2, Anti-DNA helicase, RecQ-like... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
707,00 €
Anti-WRN
Artikelnummer: E-AB-53558.120
This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein contains a nuclear localization signal in the C-terminus and...
| Schlagworte: | Anti-WRN, Anti-RECQ3, Anti-RecQ3, EC=3.1.-.-, Anti-Exonuclease WRN, Anti-RecQ protein-like 2, Anti-DNA helicase, RecQ-like... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 89,00 €
Anti-WRN
Artikelnummer: ATA-HPA028661.100
Protein function: Multifunctional enzyme that has both magnesium and ATP- dependent DNA-helicase activity and 3'->5' exonuclease activity towards double-stranded DNA with a 5'-overhang. Has no nuclease activity towards single-stranded DNA or blunt-ended double-stranded DNA. Binds preferentially to DNA substrates...
| Schlagworte: | Anti-WRN, Anti-RECQ3, Anti-RecQ3, EC=3.1.-.-, Anti-Exonuclease WRN, Anti-RecQ protein-like 2, Anti-DNA helicase, RecQ-like... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
WRN, GST-Tag Recombinant
Artikelnummer: BPS-101264
Recombinant human WRN (Werner syndrome ATP-dependent helicase), encompassing amino acids 517-1093. This construct contains an N-terminal GST-tag followed by a Thrombin cleavage site. The recombinant protein was affinity purified.
| Schlagworte: | WRN, RECQ3, 3'-5' exonuclease, RecQ protein-like 2, ATP-dependent helicase, Werner syndrome protein, DNA helicase,... |
| Anwendung: | Immunotherapy studies |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 92 kD |
483,00 €
Anti-WRN
Artikelnummer: A300-239A-T
The protein product of the Werner's syndrome (WRN) gene is the Werner syndrome ATP-dependent helicase. WRN is part of the ReqQ family of helicases that unwind DNA in preparation for replication, transcription, and repair. WRN appears to play a versatile role in cellular processes including DNA replication,...
| Schlagworte: | Anti-WRN, Anti-RECQ3, Anti-RecQ3, EC=3.1.-.-, Anti-Exonuclease WRN, Anti-RecQ protein-like 2, Anti-DNA helicase, RecQ-like... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
165,00 €