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Anti-WRN
Anti-WRN

Artikelnummer: A300-239A-T

The protein product of the Werner's syndrome (WRN) gene is the Werner syndrome ATP-dependent helicase. WRN is part of the ReqQ family of helicases that unwind DNA in preparation for replication, transcription, and repair. WRN appears to play a versatile role in cellular processes including DNA replication,...
Schlagworte: Anti-WRN, Anti-RECQ3, Anti-RecQ3, EC=3.1.-.-, Anti-Exonuclease WRN, Anti-RecQ protein-like 2, Anti-DNA helicase, RecQ-like...
Anwendung: WB, IP
Wirt: Rabbit
Spezies-Reaktivität: human
164,00 €
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WRN Helicase Activity Assay Kit
WRN Helicase Activity Assay Kit

Artikelnummer: BPS-78852

The WRN Helicase Activity Assay is a fluorogenic assay designed for screening and profiling of WRN (Werner Syndrome ATP-dependent Helicase) antagonists/inhibitors by monitoring their effect on WRN-catalyzed DNA unwinding. WRN inhibitor NCGC00063279 is also included as a control. The DNA probe is conjugated on one...
Schlagworte: WRN, RECQ3, 3'-5' exonuclease, RecQ protein-like 2, ATP-dependent helicase, Werner syndrome protein, DNA helicase,...
Anwendung: Small molecule inhibitor / antagonist screening, HTS
Spezies-Reaktivität: human
1.753,00 €
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Anti-WRN
Anti-WRN

Artikelnummer: A300-238A

The protein product of the Werners syndrome (WRN) gene is the Werner syndrome ATP-dependent helicase. WRN is part of the ReqQ family of helicases that unwind DNA in preparation for replication, transcription, and repair. WRN appears to play a versatile role in cellular processes including DNA replication,...
Schlagworte: Anti-Werner syndrome protein variant
Anwendung: WB, IP
Wirt: Rabbit
Spezies-Reaktivität: human
ab 164,00 €
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Anti-WRN (IHC)
Anti-WRN (IHC)

Artikelnummer: IHC-00407-T

The protein product of the Werners syndrome (WRN) gene is the Werner syndrome ATP-dependent helicase. WRN is part of the ReqQ family of helicases that unwind DNA in preparation for replication, transcription, and repair. WRN appears to play a versatile role in cellular processes including DNA replication,...
Schlagworte: Anti-Werner syndrome protein variant
Anwendung: IHC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 164,00 €
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NSC 617145
NSC 617145

Artikelnummer: Cay21973-1

NSC 617145 is an inhibitor of WRN helicase (IC50 = 230 nM) that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependent manner. It is selective for WRN over BLM, FANCJ, ChlR1, RecQ, and UvrD helicases, only exhibiting 7% inhibition of RECQ1 at a concentration of 5 µM. NSC...
Schlagworte: 1,1'-(2,2-dimethyl-1,3-propanediyl)bis[3,4-dichloro-1H-pyrrole-2,5-dione
Anwendung: WRN inhibitor
CAS 203115-63-3
MW: 400 D
ab 46,00 €
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Anti-WRN
Anti-WRN

Artikelnummer: A300-239A

The protein product of the Werners syndrome (WRN) gene is the Werner syndrome ATP-dependent helicase. WRN is part of the ReqQ family of helicases that unwind DNA in preparation for replication, transcription, and repair. WRN appears to play a versatile role in cellular processes including DNA replication,...
Schlagworte: Anti-Werner syndrome protein variant
Anwendung: WB, IP
Wirt: Rabbit
Spezies-Reaktivität: human
588,00 €
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Anti-WRN
Anti-WRN

Artikelnummer: ARG59158.100

Protein function: Multifunctional enzyme that has both magnesium and ATP- dependent DNA-helicase activity and 3'->5' exonuclease activity towards double-stranded DNA with a 5'-overhang. Has no nuclease activity towards single-stranded DNA or blunt-ended double- stranded DNA. Binds preferentially to DNA substrates...
Schlagworte: Anti-WRN, Anti-RECQ3, Anti-RecQ3, EC=3.1.-.-, Anti-Exonuclease WRN, Anti-RecQ protein-like 2, Anti-DNA helicase, RecQ-like...
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human
624,00 €
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Anti-WRN
Anti-WRN

Artikelnummer: E-AB-53558.120

This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein contains a nuclear localization signal in the C-terminus and...
Schlagworte: Anti-WRN, Anti-RECQ3, Anti-RecQ3, EC=3.1.-.-, Anti-Exonuclease WRN, Anti-RecQ protein-like 2, Anti-DNA helicase, RecQ-like...
Anwendung: IHC, ELISA
Wirt: Rabbit
Spezies-Reaktivität: human
ab 71,00 €
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Anti-WRN
Anti-WRN

Artikelnummer: G-CAB6855.100

Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human
ab 352,00 €
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Anti-WRN
Anti-WRN

Artikelnummer: ATA-HPA028661.100

Protein function: Multifunctional enzyme that has both magnesium and ATP- dependent DNA-helicase activity and 3'->5' exonuclease activity towards double-stranded DNA with a 5'-overhang. Has no nuclease activity towards single-stranded DNA or blunt-ended double-stranded DNA. Binds preferentially to DNA substrates...
Schlagworte: Anti-WRN, Anti-RECQ3, Anti-RecQ3, EC=3.1.-.-, Anti-Exonuclease WRN, Anti-RecQ protein-like 2, Anti-DNA helicase, RecQ-like...
Anwendung: IHC, ICC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 300,00 €
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WRN, GST-Tag Recombinant
WRN, GST-Tag Recombinant

Artikelnummer: BPS-101264

Recombinant human WRN (Werner syndrome ATP-dependent helicase), encompassing amino acids 517-1093. This construct contains an N-terminal GST-tag followed by a Thrombin cleavage site. The recombinant protein was affinity purified.
Schlagworte: WRN, RECQ3, 3'-5' exonuclease, RecQ protein-like 2, ATP-dependent helicase, Werner syndrome protein, DNA helicase,...
Anwendung: Immunotherapy studies
Exprimiert in: insect cells
Ursprungsart: human
MW: 92 kD
474,00 €
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Anti-WRN
Anti-WRN

Artikelnummer: ELK-ES20223.100

Werner syndrome RecQ like helicase(WRN) Homo sapiens This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein...
Schlagworte: Anti-WRN, Anti-RECQ3, Anti-3'-5' exonuclease, Anti-RecQ protein-like 2, Anti-ATP-dependent helicase, Anti-Werner syndrome...
Anwendung: WB, ELISA
Wirt: Rabbit
Spezies-Reaktivität: human, rat, mouse,
ab 169,00 €
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