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Zu "K10900" wurden 26 Artikel gefunden!
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Artikelnummer: A300-239A-T
The protein product of the Werner's syndrome (WRN) gene is the Werner syndrome ATP-dependent helicase. WRN is part of the ReqQ family of helicases that unwind DNA in preparation for replication, transcription, and repair. WRN appears to play a versatile role in cellular processes including DNA replication,...
Schlagworte: | Anti-WRN, Anti-RECQ3, Anti-RecQ3, EC=3.1.-.-, Anti-Exonuclease WRN, Anti-RecQ protein-like 2, Anti-DNA helicase, RecQ-like... |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
164,00 €
Artikelnummer: BPS-78852
The WRN Helicase Activity Assay is a fluorogenic assay designed for screening and profiling of WRN (Werner Syndrome ATP-dependent Helicase) antagonists/inhibitors by monitoring their effect on WRN-catalyzed DNA unwinding. WRN inhibitor NCGC00063279 is also included as a control. The DNA probe is conjugated on one...
Schlagworte: | WRN, RECQ3, 3'-5' exonuclease, RecQ protein-like 2, ATP-dependent helicase, Werner syndrome protein, DNA helicase,... |
Anwendung: | Small molecule inhibitor / antagonist screening, HTS |
Spezies-Reaktivität: | human |
1.753,00 €
Artikelnummer: A300-238A
The protein product of the Werners syndrome (WRN) gene is the Werner syndrome ATP-dependent helicase. WRN is part of the ReqQ family of helicases that unwind DNA in preparation for replication, transcription, and repair. WRN appears to play a versatile role in cellular processes including DNA replication,...
Schlagworte: | Anti-Werner syndrome protein variant |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: IHC-00407-T
The protein product of the Werners syndrome (WRN) gene is the Werner syndrome ATP-dependent helicase. WRN is part of the ReqQ family of helicases that unwind DNA in preparation for replication, transcription, and repair. WRN appears to play a versatile role in cellular processes including DNA replication,...
Schlagworte: | Anti-Werner syndrome protein variant |
Anwendung: | IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: Cay21973-1
NSC 617145 is an inhibitor of WRN helicase (IC50 = 230 nM) that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependent manner. It is selective for WRN over BLM, FANCJ, ChlR1, RecQ, and UvrD helicases, only exhibiting 7% inhibition of RECQ1 at a concentration of 5 µM. NSC...
Schlagworte: | 1,1'-(2,2-dimethyl-1,3-propanediyl)bis[3,4-dichloro-1H-pyrrole-2,5-dione |
Anwendung: | WRN inhibitor |
CAS | 203115-63-3 |
MW: | 400 D |
ab 46,00 €
Artikelnummer: A300-239A
The protein product of the Werners syndrome (WRN) gene is the Werner syndrome ATP-dependent helicase. WRN is part of the ReqQ family of helicases that unwind DNA in preparation for replication, transcription, and repair. WRN appears to play a versatile role in cellular processes including DNA replication,...
Schlagworte: | Anti-Werner syndrome protein variant |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
588,00 €
Artikelnummer: ARG59158.100
Protein function: Multifunctional enzyme that has both magnesium and ATP- dependent DNA-helicase activity and 3'->5' exonuclease activity towards double-stranded DNA with a 5'-overhang. Has no nuclease activity towards single-stranded DNA or blunt-ended double- stranded DNA. Binds preferentially to DNA substrates...
Schlagworte: | Anti-WRN, Anti-RECQ3, Anti-RecQ3, EC=3.1.-.-, Anti-Exonuclease WRN, Anti-RecQ protein-like 2, Anti-DNA helicase, RecQ-like... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
624,00 €
Artikelnummer: E-AB-53558.120
This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein contains a nuclear localization signal in the C-terminus and...
Schlagworte: | Anti-WRN, Anti-RECQ3, Anti-RecQ3, EC=3.1.-.-, Anti-Exonuclease WRN, Anti-RecQ protein-like 2, Anti-DNA helicase, RecQ-like... |
Anwendung: | IHC, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 71,00 €
Artikelnummer: G-CAB6855.100
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 352,00 €
Artikelnummer: ATA-HPA028661.100
Protein function: Multifunctional enzyme that has both magnesium and ATP- dependent DNA-helicase activity and 3'->5' exonuclease activity towards double-stranded DNA with a 5'-overhang. Has no nuclease activity towards single-stranded DNA or blunt-ended double-stranded DNA. Binds preferentially to DNA substrates...
Schlagworte: | Anti-WRN, Anti-RECQ3, Anti-RecQ3, EC=3.1.-.-, Anti-Exonuclease WRN, Anti-RecQ protein-like 2, Anti-DNA helicase, RecQ-like... |
Anwendung: | IHC, ICC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 300,00 €
Artikelnummer: BPS-101264
Recombinant human WRN (Werner syndrome ATP-dependent helicase), encompassing amino acids 517-1093. This construct contains an N-terminal GST-tag followed by a Thrombin cleavage site. The recombinant protein was affinity purified.
Schlagworte: | WRN, RECQ3, 3'-5' exonuclease, RecQ protein-like 2, ATP-dependent helicase, Werner syndrome protein, DNA helicase,... |
Anwendung: | Immunotherapy studies |
Exprimiert in: | insect cells |
Ursprungsart: | human |
MW: | 92 kD |
474,00 €
Artikelnummer: ELK-ES20223.100
Werner syndrome RecQ like helicase(WRN) Homo sapiens This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein...
Schlagworte: | Anti-WRN, Anti-RECQ3, Anti-3'-5' exonuclease, Anti-RecQ protein-like 2, Anti-ATP-dependent helicase, Anti-Werner syndrome... |
Anwendung: | WB, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, rat, mouse, |
ab 169,00 €