- Suchergebnis für K10799
Cookie-Einstellungen
Diese Website benutzt Cookies, die für den technischen Betrieb der Website erforderlich sind und stets gesetzt werden. Andere Cookies, die den Komfort bei Benutzung dieser Website erhöhen, der Direktwerbung dienen oder die Interaktion mit anderen Websites und sozialen Netzwerken vereinfachen sollen, werden nur mit Ihrer Zustimmung gesetzt.
Konfiguration
Technisch erforderlich
Diese Cookies sind für die Grundfunktionen des Shops notwendig.
"Alle Cookies ablehnen" Cookie
"Alle Cookies annehmen" Cookie
Ausgewählter Shop
CSRF-Token
Cookie-Einstellungen
FACT-Finder Tracking
Individuelle Preise
Kundenspezifisches Caching
Session
Währungswechsel
Komfortfunktionen
Diese Cookies werden genutzt um das Einkaufserlebnis noch ansprechender zu gestalten, beispielsweise für die Wiedererkennung des Besuchers.
Facebook-Seite in der rechten Blog - Sidebar anzeigen
Merkzettel
Statistik & Tracking
Endgeräteerkennung
Kauf- und Surfverhalten mit Google Tag Manager
Partnerprogramm
Zu "K10799" wurden 67 Artikel gefunden!
Filter schließen
Filtern nach:
Für die Filterung wurden keine Ergebnisse gefunden!
Artikelnummer: ELK-ELK3071.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human TNKS1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TNKS1. Next,...
Schlagworte: | TANK1, ARTD5, TNKS-1, Tankyrase-1, Tankyrase I, Poly [ADP-ribose] polymerase 5A, Poly [ADP-ribose] polymerase tankyrase-1,... |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: Cay13596-1
The Wnt signaling pathway is integral to normal biological processes and inappropriately active in many cancers. It is regulated through degradation of the downstream effector beta-catenin via a complex consisting of the tumor suppressor APC, axin, and glycogen synthase kinase 3 (GSK3). Axin is the...
Schlagworte: | 3,5,7,8-tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one |
Anwendung: | TNKS inhibitor |
CAS | 284028-89-3 |
MW: | 312.3 D |
ab 20,00 €
Artikelnummer: A302-398A
Protein function: Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation (PARsylation) of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction...
Schlagworte: | Anti-TNKS, Anti-ARTD5, Anti-TANK1, Anti-TNKS-1, Anti-PARP5A, EC=2.4.2.30, Anti-Tankyrase-1, Anti-Tankyrase I, Anti-Poly... |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: Cay14440-5
The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species. PJ-34 is an inhibitor of PARPs which can be used in cells or in animals. It binds and inhibits the PARP tankyrase1 (IC50 = 1 µM). PJ-34 also...
Schlagworte: | N-(5,6-dihydro-6-oxo-2-phenanthridinyl)-2-(dimethylamino)-acetamide, monohydrochloride |
Anwendung: | PARP inhibitor |
CAS | 344458-15-7 |
MW: | 331.8 D |
ab 50,00 €
Artikelnummer: A302-399A-T
Protein function: Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation (PARsylation) of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction...
Schlagworte: | Anti-TNKS, Anti-ARTD5, Anti-TANK1, Anti-TNKS-1, Anti-PARP5A, EC=2.4.2.30, Anti-Tankyrase-1, Anti-Tankyrase I, Anti-Poly... |
Anwendung: | WB, IP, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: BPS-80504
TNKS1 (TRF1-interacting ankyrin-related ADP-ribose polymerase 1), also known as PARP5A, TANK1, or tanykyrase-1 (GenBank Accession No. NM_003747), a.a. 1000-1328(end), with N-terminal GST-tag, MW=62.5 kDa, expressed in Sf9 cells via a baculovirus expression system. Autoribosylation reaction is conducted in wells...
Schlagworte: | ARTD5, TANK1, TNKS-1, Tankyrase-1, Tankyrase I, Poly [ADP-ribose] polymerase 5A, Poly [ADP-ribose] polymerase tankyrase-1,... |
Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
Exprimiert in: | Baculovirus |
Ursprungsart: | human |
MW: | 62.5 kD |
759,00 €
Artikelnummer: BPS-80505
TNKS2 (TRF1-interacting ankyrin-related ADP-ribose polymerase 2), also known as PARP5B/C, tanykyrase-2, or TNKL (GenBank Accession No. NM_025235), a.a. 667-1166(end), with N-terminal GST-tag, MW=80.5 kDa, expressed in Sf9 cells via a baculovirus expressio
Schlagworte: | TANK2, ARTD6, TNKS-2, Tankyrase-2, Tankyrase II, Tankyrase-like protein, Tankyrase-related protein, Poly [ADP-ribose]... |
Anwendung: | Enzyme kinetics, inhibitor screening |
MW: | 80.5 kD |
759,00 €
Artikelnummer: LKT-X0384.5
Tankyrase inhibitor.
Schlagworte: | 2-[4-(trifluoromethyl)phenyl]-7,8-dihydro-5H-thiino[4,3-d]pyrimidin-4-ol |
Anwendung: | Tankyrase inhibitor |
CAS | 284028-89-3 |
MW: | 312.31 D |
ab 94,00 €
Artikelnummer: Cay22934-1
G007-LK is an inhibitor of the tankyrases TNKS1 and TNKS2 (IC50s = 46 and 25 nM, respectively). It is selective for TNKS1 and TNKS2 over a panel of 90 kinases, 16 phosphatases, and 73 G protein-coupled receptors (GPCRs) when used at a concentration of 10 µM. G007-LK inhibits colony formation of COLO 320 DM and SW403...
Schlagworte: | Tankyrase 1/2 Inhibitor VI,... |
Anwendung: | TNKS / TNKS2 inhibitor |
CAS | 1380672-07-0 |
MW: | 530 D |
ab 43,00 €
Artikelnummer: Cay16260-5
JW 55 is an inhibitor of the PARP domain of tankyrases (TNKS) 1 and 2 (IC50s = 1.9 and 0.83 µM, respectively). By inhibiting TNKS1/2, JW 55 stabilizes Axin2 and increases degradation of beta-catenin, inhibiting the beta-catenin signaling pathway (IC50 = 470 nM). It has been shown to decrease canonical Wnt signaling...
Schlagworte: | Tankyrase 1/2 Inhibitor IV,... |
Anwendung: | Wnt/beta-catenin signaling inhibitor, Tankyrase inhibitor |
CAS | 664993-53-7 |
MW: | 434.5 D |
ab 92,00 €
Artikelnummer: Cay19898-1
AZ 6102 is an inhibitor of tankyrases (TNKS) 1 and 2 with IC50 values of 3 and 1 nM, respectively. It demonstrates 100-fold selectivity for TNKS1/2 over PARP1, PARP2, and PARP6 (IC50s = 2, 0.5, and >3 µM, respectively). By inhibiting TNKS1/2, AZ6120 has been shown to inhibit Wnt signaling in DLD-1 cells with an IC50...
Schlagworte: | rel-2-[4-[6-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-4-methyl-3-pyridinyl]phenyl]-3,7-dihydro-7-methyl-4H-pyrrolo[2,3-d]pyrimi... |
Anwendung: | TNKS1/2 inhibitor |
CAS | 1645286-75-4 |
MW: | 428.5 D |
ab 50,00 €
Artikelnummer: Cay19930-5
NVP-TNKS656 is an orally bioavailable inhibitor of tankyrase 2 (TNKS2, IC50 = 6 nM). It is selective for TNKS2 over poly(ADP-ribose) polymerase (PARP) 1 and 2 (IC50s = >19 and 32 nM, respectively). NVP-TNKS656 inhibits Wnt ligand-induced signaling with an IC50 value of 3.5 nM in an HEK293 cell reporter assay. In...
Schlagworte: | N-(cyclopropylmethyl)-4-(4-methoxybenzoyl)-N-[(3,5,7,8-tetrahydro-4-oxo-4H-pyrano[4,3-d]pyrimidin-2-yl)methyl]-1-piperidin... |
Anwendung: | Tankyrase inhibitor |
CAS | 1419949-20-4 |
MW: | 494.6 D |
ab 77,00 €