Zu "K10790" wurden 29 Artikel gefunden!
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NEU
Enzolution(R) TREX1 Assay System
Artikelnummer: BBL-3029-10K
The Enzolution(R) TREX1 Assay System is intended for use with the Transcreener(R) dAMP FP Assay Kit (Part #3028) to measure enzymatic activity for TREX1 (also known as Three Prime Repair Exonuclease 1). TREX1 is the major exonuclease responsible for degrading cytosolic DNA, and it plays an important role in...
| Schlagworte: | TREX1, Deoxyribonuclease III, 3'-5' exonuclease TREX1, Three-prime repair exonuclease 1 |
| Anwendung: | HTS, drug discovery, enzyme assays |
ab 626,00 €
NEU
Recombinant TREX1 Enzyme, Active, Human
Artikelnummer: BBL-2260
Active, human Three Prime Repair Exonculease 1 enzyme, His-tagged protein expressed and purified from baculovirus-infected insect cells. The enzyme has been thoroughly validated with Transcreener dAMP Exonculease Assay Kit. For specific activity, please refer to the Certificate of Analysis for each individual enzyme...
| Schlagworte: | TREX1, Deoxyribonuclease III, 3'-5' exonuclease TREX1, Three-prime repair exonuclease 1 |
| Anwendung: | HTS, drug discovery, enzyme assays |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
ab 341,00 €
NEU
Transcreener(R) dAMP FP Assay
Artikelnummer: BBL-3028-10K
The Transcreener(R) dAMP FP Assay is a far-red, competitive fluorescence polarization (FP) assay. The assay is designed to be used with exonuclease enzymes such as TREX1 (also known as Three Prime Repair Exonuclease 1), that produce the product dAMP (deoxyadenosine monophosphate, deoxyadenylic acid, or...
| Schlagworte: | Exonuclease Activity Assay, Exonuclease Inhibitor Screening Assay |
| Anwendung: | HTS, drug discovery, enzyme assays |
| Spezies-Reaktivität: | human |
ab 827,00 €
TREX1 Protein, Human, Recombinant (His & MBP)
Artikelnummer: TGM-TMPH-02201-10ug
Description: TREX1 Protein, Human, Recombinant (His & MBP) is expressed in Baculovirus insect cells with N-10xHis-MBP and C-6xHis tag. The predicted molecular weight is 83.6 kDa and the accession number is Q9NSU2.
| Schlagworte: | Three-prime repair exonuclease 1 , Deoxyribonuclease III (DNase III) , 3'-5' exonuclease TREX1 , TREX1 |
| MW: | 83.6 kD |
ab 166,00 €
Anti-Recombinant TREX1, clone A643
Artikelnummer: E-AN301927L.100
TREX1 is a broadly expressed 3' to 5' exonuclease that acts on single-stranded DNA (ssDNA) to negatively regulate the interferon-stimulatory DNA (ISD) response. In humans, there are three TREX1 isoforms generated through alternative splicing with predicted molecular weights of 32, 33, and 39 kDa. The transcript for...
| Schlagworte: | Anti-Trex1, Anti-3'-5' exonuclease TREX1, Anti-Three-prime repair exonuclease 1, Recombinant TREX1 Monoclonal Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 303,00 €
Anti-TRIM25
Artikelnummer: 600-401-FP1
Anti-TRIM25 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with TRIM25 from other sources has not been determined. Protein function: Major cellular 3'-to-5' DNA exonuclease which digests single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) with...
| Schlagworte: | Anti-TREX1, Anti-DNase III, EC=3.1.11.2, Anti-3'-5' exonuclease TREX1, Anti-Three-prime repair exonuclease 1 |
| Anwendung: | ELISA, IFM, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
848,00 €
Anti-TREX1
Artikelnummer: NSJ-R32336
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Three prime repair exonuclease 1 is an enzyme that in humans is encoded by the TREX1 gene. This gene encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA...
| Schlagworte: | Anti-TREX1, Anti-DNase III, EC=3.1.11.2, Anti-3'-5' exonuclease TREX1, Anti-Three-prime repair exonuclease 1, TREX1 Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
790,00 €
Anti-TREX1
Artikelnummer: ARG59391.100
Protein function: Major cellular 3'-to-5' DNA exonuclease which digests single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) with mismatched 3' termini. Prevents cell-intrinsic initiation of autoimmunity. Acts by metabolizing DNA fragments from endogenous retroelements, including L1, LTR and SINE elements....
| Schlagworte: | Anti-DNase III, EC=3.1.11.2, Anti-Deoxyribonuclease III, Anti-3'-5' exonuclease TREX1, Anti-Three-prime repair exonuclease 1 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
707,00 €
Anti-TREX1
Artikelnummer: ATA-HPA035437.100
Protein function: Major cellular 3'-to-5' DNA exonuclease which digests single- stranded DNA (ssDNA) and double-stranded DNA (dsDNA) with mismatched 3' termini. Prevents cell-intrinsic initiation of autoimmunity. Acts by metabolizing DNA fragments from endogenous retroelements, including L1, LTR and SINE elements....
| Schlagworte: | Anti-DNase III, EC=3.1.11.2, Anti-Deoxyribonuclease III, Anti-3'-5' exonuclease TREX1, Anti-Three-prime repair exonuclease 1 |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 246,00 €
Anti-TREX1
Artikelnummer: ATA-HPA046721.100
Protein function: Major cellular 3'-to-5' DNA exonuclease which digests single- stranded DNA (ssDNA) and double-stranded DNA (dsDNA) with mismatched 3' termini. Prevents cell-intrinsic initiation of autoimmunity. Acts by metabolizing DNA fragments from endogenous retroelements, including L1, LTR and SINE elements....
| Schlagworte: | Anti-DNase III, EC=3.1.11.2, Anti-Deoxyribonuclease III, Anti-3'-5' exonuclease TREX1, Anti-Three-prime repair exonuclease 1 |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 369,00 €
Three-prime repair exonuclease 1 (TREX1), human, recombinant
Artikelnummer: CSB-BP865133HUi2.1
Organism: Homo sapiens (Human). Source: Baculovirus. Expression Region: 1-369aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-MBP-tagged and C-terminal 6xHis-tagged. Target Protein Sequence: MGPGARRQGR IVQGRPEMCF CPPPTPLPPL RILTLGTHTP TPCSSPGSAA GTYPTMGSQA LPPGPMQTLI FFDMEATGLP FSQPKVTELC LLAVHRCALE...
| Schlagworte: | DNase III, EC=3.1.11.2, Deoxyribonuclease III, 3'-5' exonuclease TREX1, Three-prime repair exonuclease 1, Recombinant... |
| Anwendung: | Activity not tested |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
| MW: | 83.6 kD |
ab 489,00 €
Three-prime repair exonuclease 1 (Trex1), mouse, recombinant
Artikelnummer: CSB-EP821009MO.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 1-314aa. Protein Length: Full length. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: MGSQTLPHGH MQTLIFLDLE ATGLPSSRPE VTELCLLAVH RRALENTSIS QGHPPPVPRP PRVVDKLSLC IAPGKACSPG ASEITGLSKA ELEVQGRQRF DDNLAILLRA...
| Schlagworte: | 3'-5' exonuclease TREX1, Three-prime repair exonuclease 1, Recombinant Mouse Three-prime repair exonuclease 1 (Trex1) |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 41.1 kD |
ab 364,00 €