Zu "K10747" wurden 47 Artikel gefunden!
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Anti-DNA Ligase 1
Artikelnummer: A301-136A-T
Protein function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. [The UniProt Consortium]
| Schlagworte: | Anti-LIG1, Anti-DNA ligase 1, Anti-DNA ligase I, Anti-Polydeoxyribonucleotide synthase [ATP] 1 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
L189
Artikelnummer: Cay18374-10
L189 is a competitive inhibitor of DNA ligases I, III, and IV (IC50s = 5, 9, and 5 µM, respectively). It blocks DNA binding (Ki = 5 µM for DNA ligase I), increasing the cytotoxicity of DNA-damaging agents, including ionizing radiation. L189 preferentially inhibits the interaction of the ligase with damaged DNA,...
| Schlagworte: | 6-amino-2,3-dihydro-5-[(phenylmethylene)amino]-2-thioxo-4(1H)-pyrimidinone |
| Anwendung: | DNA ligase I, III, IV inhibitor |
| CAS | 64232-83-3 |
| MW: | 246.3 D |
ab 128,00 €
Anti-LIG1
Artikelnummer: ARG55337.100
Protein function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. [The UniProt Consortium]
| Schlagworte: | Anti-LIG1, EC=6.5.1.1, Anti-DNA ligase 1, Anti-DNA ligase I, Anti-Polydeoxyribonucleotide synthase [ATP] 1 |
| Anwendung: | WB, ICC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
707,00 €
Anti-LIG1 / DNA ligase I, Internal (near C-Terminus)
Artikelnummer: ARG64962.100
Protein function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. [The UniProt Consortium]
| Schlagworte: | Anti-LIG1, EC=6.5.1.1, Anti-DNA ligase 1, Anti-DNA ligase I, Anti-Polydeoxyribonucleotide synthase [ATP] 1 |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Anti-LIG1
Artikelnummer: NSJ-R35806-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: DNA ligase 1 Protein function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. [The UniProt Consortium]
| Schlagworte: | Anti-LIG1, EC=6.5.1.1, Anti-DNA ligase 1, Anti-DNA ligase I, Anti-Polydeoxyribonucleotide synthase [ATP] 1, LIG1 Antibody |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
L67
Artikelnummer: Cay22941-10
L67 is a competitive inhibitor of DNA ligases I and III (IC50s = 10 and 10 µM for human DNA ligase I and human ligase IIIbeta). It blocks DNA binding (Ki = 10 µM), increasing the cytotoxicity of DNA-damaging agents. It also inhibits mitochondrial DNA ligase IIIalpha and induces the production of reactive oxygen...
| Schlagworte: | N-(3,5-dibromo-4-methylphenyl)-glycine, 2-[(2-hydroxy-5-nitrophenyl)methylene]hydrazide |
| Anwendung: | DNA ligase I / III inhibitor |
| CAS | 325970-71-6 |
| MW: | 486.1 D |
ab 145,00 €
Anti-LIG1
Artikelnummer: E-AB-14958.120
This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents....
| Schlagworte: | Anti-LIG1, Anti-DNA ligase I, Anti-DNA ligase 1, Anti-Polydeoxyribonucleotide synthase [ATP] 1, LIG1 Polyclonal Antibody |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Anti-LIG1
Artikelnummer: ATA-HPA048071.100
Protein function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 98% and to rat: 95%
| Schlagworte: | Anti-LIG1, Anti-DNA ligase 1, Anti-DNA ligase I, Anti-Polydeoxyribonucleotide synthase [ATP] 1 |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
Anti-LIG1
Artikelnummer: ATA-HPA041431.100
Protein function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 86% and to rat: 87%
| Schlagworte: | Anti-LIG1, Anti-DNA ligase 1, Anti-DNA ligase I, Anti-Polydeoxyribonucleotide synthase [ATP] 1 |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
L82-G17
Artikelnummer: Cay41041-10
L82-G17 is an uncompetitive inhibitor of DNA ligase I. It increases the retention of DNA ligase I, but not DNA ligase III, on nicked DNA-coated beads in a cell-free assay, as well as decreases the proliferation of HeLa cells when used at a concentration of 20 µM.Formal Name:...
| Schlagworte: | 4-chloro-5-(2-(3-hydroxybenzylidene)hydrazineyl)pyridazin-3(2H)-one |
| Anwendung: | DNA ligase I inhibitor |
| CAS | 92285-87-5 |
| MW: | 264.7 D |
ab 186,00 €
DNA ligase 1 (LIG1), human, recombinant
Artikelnummer: CSB-EP012930HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-919aa. Protein Length: Full Length. Tag Info: N-terminal GST-tagged. Target Protein Sequence: MQRSIMSFFH PKKEGKAKKP EKEASNSSRE TEPPPKAALK EWNGVVSESD SPVKRPGRKA ARVLGSEGEE EDEALSPAKG QKPALDCSQV SPPRPATSPE NNASLSDTSP MDSSPSGIPK RRTARKQLPK RTIQEVLEEQ...
| Schlagworte: | LIG1, DNA ligase 1, DNA ligase I, Polydeoxyribonucleotide synthase [ATP] 1, Recombinant Human DNA ligase 1 (LIG1) |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 128.7 kD |
ab 219,00 €
Anti-LIG1
Artikelnummer: CSB-PA002165.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-LIG1, Anti-DNA ligase I, Anti-DNA ligase 1, Anti-Polydeoxyribonucleotide synthase [ATP] 1, DNA ligase 1 antibody, DNA... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 126,00 €