Zu "K10685" wurden 23 Artikel gefunden!
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Anti-UBA2 / SUMO-activating enzyme subunit 2 / SAE2,...
Artikelnummer: NSJ-RQ5505
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Ubiquitin-like 1-activating enzyme E1B (UBLE1B) also known as SUMO-activating enzyme subunit 2 (SAE2) is an enzyme that in humans is encoded by the UBA2 gene. Posttranslational modification of proteins by the addition of the small protein SUMO, or sumoylation,...
| Schlagworte: | Anti-SAE2, Anti-UBA2, Anti-HRIHFB2115, EC=2.3.2.-, Anti-SUMO-activating enzyme subunit 2, Anti-Ubiquitin-like 1-activating... |
| Anwendung: | WB, FC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat |
755,00 €
TAK-981
Artikelnummer: Cay32741-1
TAK-981 is an inhibitor of SUMO-activating enzyme (SAE, IC50 = in vitro. TAK-981 upregulates the expression of IFN-regulated genes in the blood and tumor tissue in an A20 syngeneic lymphoma mouse model. It also decreases intratumor levels of SUMOlyated proteins and reduces tumor growth in the same model.Formal Name:...
| Schlagworte: | [(1R,2S,4R)-4-[[5-[[4-[(1R)-7-chloro-1,2,3,4-tetrahydro-1-isoquinolinyl]-5-methyl-2-thienyl]carbonyl]-4-pyrimidinyl]amino]... |
| Anwendung: | SUMO-activating enzyme (SAE) inhibitor |
| CAS | 1858276-04-6 |
| MW: | 578.1 D |
ab 92,00 €
Anti-SAE2
Artikelnummer: A302-925A
Protein function: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. [The UniProt Consortium]
| Schlagworte: | Anti-UBA2, Anti-SAE2, Anti-HRIHFB2115, EC=2.3.2.-, Anti-SUMO-activating enzyme subunit 2, Anti-Ubiquitin-like 1-activating... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 164,00 €
Anti-SAE2
Artikelnummer: A302-926A
Protein function: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. [The UniProt Consortium]
| Schlagworte: | Anti-UBA2, Anti-SAE2, Anti-HRIHFB2115, EC=2.3.2.-, Anti-SUMO-activating enzyme subunit 2, Anti-Ubiquitin-like 1-activating... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 164,00 €
Anti-SAE2
Artikelnummer: 600-401-ED6
Anti-SAE2 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with SAE2 from other sources has not been determined. Protein function: The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO...
| Schlagworte: | Anti-UBA2, Anti-SAE2, EC=6.3.2.-, Anti-HRIHFB2115, Anti-SUMO-activating enzyme subunit 2, Anti-Ubiquitin-like 1-activating... |
| Anwendung: | ELISA, IFM, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
684,00 €
Anti-UBA2 / SUMO-activating enzyme subunit 2 / SAE2
Artikelnummer: NSJ-RQ4241
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Ubiquitin-like 1-activating enzyme E1B (UBLE1B) also known as SUMO-activating enzyme subunit 2 (SAE2) is an enzyme that in humans is encoded by the UBA2 gene. Posttranslational modification of proteins by the addition of the small protein SUMO, or sumoylation,...
| Schlagworte: | Anti-UBA2, Anti-SAE2, EC=2.3.2.-, Anti-HRIHFB2115, Anti-SUMO-activating enzyme subunit 2, Anti-Ubiquitin-like 1-activating... |
| Anwendung: | WB, IHC (paraffin), IF/ICC, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
755,00 €
Anti-UBA2 / SAE2
Artikelnummer: ARG59199.50
Protein function: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. [The UniProt Consortium]
| Schlagworte: | Anti-UBA2, Anti-SAE2, Anti-HRIHFB2115, EC=2.3.2.-, Anti-SUMO-activating enzyme subunit 2, Anti-Ubiquitin-like 1-activating... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
520,00 €
Anti-UBA2 / SAE2
Artikelnummer: ARG59243.100
Protein function: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. [The UniProt Consortium]
| Schlagworte: | Anti-UBA2, Anti-SAE2, Anti-HRIHFB2115, EC=2.3.2.-, Anti-SUMO-activating enzyme subunit 2, Anti-Ubiquitin-like 1-activating... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
624,00 €
Anti-UBA2
Artikelnummer: G-CAB17342.100
WB 1:500 - 1:1000. Protein function: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. [The UniProt...
| Schlagworte: | Anti-SAE2, Anti-UBA2, EC=2.3.2.-, Anti-HRIHFB2115, Anti-SUMO-activating enzyme subunit 2, Anti-Ubiquitin-like 1-activating... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | rat |
ab 352,00 €
Anti-UBA2
Artikelnummer: ATA-HPA041436.100
Protein function: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. [The UniProt Consortium] Buffer: 40%...
| Schlagworte: | Anti-SAE2, Anti-UBA2, EC=2.3.2.-, Anti-HRIHFB2115, Anti-SUMO-activating enzyme subunit 2, Anti-Ubiquitin-like 1-activating... |
| Anwendung: | ICC, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 335,00 €
ML-792
Artikelnummer: Cay36820-25
ML-792 is an inhibitor of SUMO-activating enzyme (SAE, IC50s = 0.003 and 0.011 µM with small ubiquitin-related modifier 1 (SUMO-1) or SUMO-2, respectively, as the ubiquitin-like proteins). It is selective for SAE over NEDD8-activating enzyme (NAE) and ubiquitin-activating enzyme (UAE, IC50s = 32 and >100 µM,...
| Schlagworte: | sulfamic acid,... |
| Anwendung: | SUMO-activating enzyme inhibitor |
| CAS | 1644342-14-2 |
| MW: | 551.4 D |
ab 204,00 €
Anti-UBA2
Artikelnummer: ELK-ES3661.100
Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1, MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et...
| Schlagworte: | Anti-UBA2, Anti-SAE2, Anti-HRIHFB2115, EC=2.3.2.-, Anti-SUMO-activating enzyme subunit 2, Anti-Ubiquitin-like 1-activating... |
| Anwendung: | WB, IHC, IF, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat, mouse, |
ab 169,00 €