Zu "K10684" wurden 61 Artikel gefunden!
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Anti-SAE1 Monoclonal Antibody
Artikelnummer: E-AN200081P.100
SAE1 belongs to the ubiquitin-activating E1 family. It is a heterodimer that acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It functions as a UBLI E1 ligase mediating the ATP-dependent activation of UBL1. SAE1 binds with UBLE1A and UBLE1B to form a heterodimer which can bind UBL1. SAE1 also...
| Schlagworte: | SAE1, AOS1, SAE1 Monoclonal Antibody |
| Anwendung: | ICC/IF |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
389,00 €
Anacardic Acid monoene
Artikelnummer: Cay18422-1
Extracts of the leaves and fruit of Ginkgo plants have long been used in traditional medicine and have multiple potential therapeutic applications, including ameliorating dementia. However, ginkgolic acids, 2-hydroxy-6-alkylbenzoic acids related to anacardic acids, may be deleterious components in these extracts....
| Schlagworte: | Anacardic Acid 15:1, Ginkgolic Acid I, Ginkogolic Acid C15:1, 2-hydroxy-6-(8Z)-8-pentadecenyl-benzoic acid |
| Anwendung: | SUMOylation inhibitor |
| CAS | 22910-60-7 |
| MW: | 346.5 D |
ab 93,00 €
Anti-phospho-SUMO Activating Enzyme E1 (SAE1) (Ser185)
Artikelnummer: 600-401-B24
Protein function: The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. [The UniProt Consortium]
| Schlagworte: | Anti-phospho-AOS1, Anti-phospho-SAE1, Anti-phospho-SUMO-activating enzyme subunit 1, Anti-phospho-Ubiquitin-like... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 180,00 €
COH000
Artikelnummer: Cay34906-5
COH000 is an inhibitor of SUMO-activating enzyme (SAE, IC50 = 0.2 µM), a heterodimer composed of SAE1 and SAE2. It is selective for SAE over ubiquitin-activating enzyme (UAE) and NEDD8-activating enzyme (NAE) at 10 µM. COH000 induces degradation of SAE2 in HCT116 human colon cancer cells. COH000 (10 mg/kg) induces...
| Schlagworte: | (1R,4S)-1-[(1R)-2-(4-methylphenyl)-1-(phenylamino)ethyl]-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylic acid,... |
| Anwendung: | SUMO-activating enzyme inhibitor |
| CAS | 1534358-79-6 |
| MW: | 419.5 D |
ab 99,00 €
ML-792
Artikelnummer: TGM-T16102-2mg
Description: ML-792 is a specific small ubiquitin-like modifier (SUMO)-activating enzyme (SAE) inhibitor. Compared with NAE/NEDD8 and UAE/ubiquitin (IC50s of 32 µM and >100 µM, respectively), ML-792 is an effective and selective inhibitor of SAE/SUMO1 and SAE/SUMO2 in enzymatic assays (IC50s of 3 and 11 nM,...
| Anwendung: | SUMO-activating enzyme inhibitor |
| CAS | 1644342-14-2 |
| MW: | 551.41 D |
ab 79,00 €
Anti-SAE1 / AOS1, C-terminal
Artikelnummer: ARG63368.100
Protein function: The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. [The UniProt Consortium]
| Schlagworte: | Anti-SAE1, Anti-AOS1 |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Anti-SAE1
Artikelnummer: A302-924A
Protein function: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. [The UniProt Consortium]
| Schlagworte: | Anti-AOS1, Anti-SAE1 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Human SAE1 ELISA Kit
Artikelnummer: G-HUFI01924.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Anti-SUMO Activating Enzyme E1
Artikelnummer: 200-401-913
Protein function: The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. [The UniProt Consortium]
| Schlagworte: | Anti-AOS1, Anti-SAE1, Anti-SUMO-activating enzyme subunit 1, Anti-Ubiquitin-like 1-activating enzyme E1A |
| Anwendung: | ELISA, IFM, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
812,00 €
Anti-SUMO Activating Enzyme E1 (SAE1)
Artikelnummer: 600-401-C51
This purified antibody is directed against human SUMO Activating Enzyme E1 protein. The product was purified from monospecific antiserum by affinity chromatography. This antibody is specific for human SAE1 protein. A BLAST analysis using the sequence of the immunizing peptide was used to suggest that this antibody...
| Schlagworte: | Anti-SAE1, Anti-AOS1, Anti-SUMO-activating enzyme subunit 1, Anti-Ubiquitin-like 1-activating enzyme E1A |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, bovine, mouse, rat, dog |
733,00 €
Anti-SUMO Activating Enzyme E1 (SAE1)
Artikelnummer: 600-401-C51S
This purified antibody is directed against human SUMO Activating Enzyme E1 protein. The product was purified from monospecific antiserum by affinity chromatography. This antibody is specific for human SAE1 protein. A BLAST analysis using the sequence of the immunizing peptide was used to suggest that this antibody...
| Schlagworte: | Anti-SAE1, Anti-AOS1, Anti-SUMO-activating enzyme subunit 1, Anti-Ubiquitin-like 1-activating enzyme E1A |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, bovine, mouse, rat, dog |
180,00 €
Anti-SAE1
Artikelnummer: NSJ-R34751-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: SUMO1 activating enzyme subunit 1, AOS1 Protein function: The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins...
| Schlagworte: | Anti-SAE1, Anti-AOS1, SAE1 Antibody |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €