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Zu "K10605" wurden 104 Artikel gefunden!
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Artikelnummer: A700-319
BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity....
Schlagworte: | Anti-Breast cancer type 1 susceptibility protein homolog |
Anwendung: | WB, IP, FC |
Wirt: | Rabbit |
Spezies-Reaktivität: | mouse |
ab 172,00 €
Artikelnummer: A300-000A-T
BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity....
Schlagworte: | Anti-BRCA1, Anti-RNF53, Anti-RING finger protein 53, Anti-RING-type E3 ubiquitin transferase BRCA1, Anti-Breast cancer... |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
164,00 €
Artikelnummer: A300-003A-T
BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity....
Schlagworte: | Anti-phospho-BRCA1, Anti-phospho-RNF53, Anti-phospho-RING finger protein 53, Anti-phospho-RING-type E3 ubiquitin... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
164,00 €
Artikelnummer: A300-004A-T
BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity....
Schlagworte: | Anti-phospho-BRCA1, Anti-phospho-RNF53, Anti-phospho-RING finger protein 53, Anti-phospho-RING-type E3 ubiquitin... |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
164,00 €
Artikelnummer: NSJ-RQ7150
0.5mg/ml if reconstituted with 0.2ml sterile DI water. BRCA1, mapped to 17q21.3, is also known as BRCC1. This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage...
Schlagworte: | Anti-RNF53, Anti-BRCA1, Anti-RING finger protein 53, Anti-RING-type E3 ubiquitin transferase BRCA1, Anti-Breast cancer... |
Anwendung: | WB, FC, Direct ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
755,00 €
Artikelnummer: ELK-ELK1904.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human BRCA1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human BRCA1. Next,...
Schlagworte: | BRCA1, RNF53, RING finger protein 53, RING-type E3 ubiquitin transferase BRCA1, Breast cancer type 1 susceptibility protein |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: A300-000A
Protein function: E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3...
Schlagworte: | Anti-BRCA1, Anti-RNF53, Anti-RING finger protein 53, Anti-RING-type E3 ubiquitin transferase BRCA1, Anti-Breast cancer... |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
588,00 €
Artikelnummer: A300-001A
Protein function: E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3...
Schlagworte: | Anti-phospho-BRCA1, Anti-phospho-RNF53, Anti-phospho-RING finger protein 53, Anti-phospho-RING-type E3 ubiquitin... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: A301-378A-T
Protein function: E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3...
Schlagworte: | Anti-BRCA1, Anti-RNF53, Anti-RING finger protein 53, Anti-RING-type E3 ubiquitin transferase BRCA1, Anti-Breast cancer... |
Anwendung: | IP, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: A300-008A-T
Protein function: E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3...
Schlagworte: | Anti-phospho-BRCA1, Anti-phospho-RNF53, Anti-phospho-RING finger protein 53, Anti-phospho-RING-type E3 ubiquitin... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: Cay14167-100
The BRCA1 C-terminal (BRCT) domain is a modular unit of ~100 amino acids that folds independently and recognizes linear phosphoserine or phosphothreonine regions to mediate protein-protein and protein-DNA interactions. BRCT domains were initially recognized in the C-terminal region of the breast cancer protein...
Schlagworte: | BRCA1, RNF53, RING finger protein 53, RING finger protein 53, RING-type E3 ubiquitin transferase BRCA1, RING-type E3... |
Anwendung: | Binding assays |
Exprimiert in: | E.coli |
MW: | 53,3 kD |
642,00 €
Artikelnummer: ARG51129.100
Protein function: E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3...
Schlagworte: | Anti-RNF53, Anti-BRCA1, Anti-RING finger protein 53, Anti-RING-type E3 ubiquitin transferase BRCA1, Anti-Breast cancer... |
Anwendung: | ICC, IF, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 436,00 €