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Zu "K10591" wurden 24 Artikel gefunden!
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Artikelnummer: NSJ-RQ7237
0.5mg/ml if reconstituted with 0.2ml sterile DI water. E3 ubiquitin-protein ligase NEDD4, also known as neural precursor cell expressed developmentally down-regulated protein 4 (NEDD4), is an enzyme that in humans is encoded by the NEDD4 gene. This gene is the founding member of the NEDD4 family of HECT ubiquitin...
Schlagworte: | Anti-Nedd4, Anti-NEDD-4, Anti-E3 ubiquitin-protein ligase NEDD4, Anti-HECT-type E3 ubiquitin transferase NEDD4,... |
Anwendung: | WB, IHC (paraffin), FC, Direct ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | mouse, rat |
755,00 €
Artikelnummer: BPS-80404
Human Nedd 4 (GenBank Accession No. NM_006154), amino-acids 150-end, with N-terminal DDDDK tag (FLAG) MW= 86 kDa, expressed in a Baculovirus infected Sf9 cell expression system.Useful in conjunction with E1 and E2 for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Schlagworte: | PIG53, NEDD4, NEDD-4, KIAA0093, E3 ubiquitin-protein ligase NEDD4, HECT-type E3 ubiquitin transferase NEDD4, Cell... |
Anwendung: | Enzyme kinetics, inhibitor screening |
MW: | 86 kD |
569,00 €
Artikelnummer: 600-401-B05S
Protein function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Involved in the pathway leading to the degradation of VEGFR- 2/KDFR, independently of its ubiquitin-ligase...
Schlagworte: | Anti-NEDD-4, EC=6.3.2.-, Anti-E3 ubiquitin-protein ligase NEDD4, Anti-Cell proliferation-inducing gene 53 protein,... |
Anwendung: | ELISA, IFM, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, horse, macaque |
ab 180,00 €
Artikelnummer: ARG55793.100
Protein function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Specifically ubiquitinates 'Lys-63' in target proteins (PubMed:23644597). Involved in the pathway leading to the...
Schlagworte: | Anti-PIG53, Anti-NEDD4, Anti-NEDD-4, Anti-KIAA0093, EC=6.3.2.-, Anti-E3 ubiquitin-protein ligase NEDD4, Anti-Cell... |
Anwendung: | WB, IHC (paraffin), FC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
584,00 €
Artikelnummer: A303-253A
Protein function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Specifically ubiquitinates 'Lys-63' in target proteins (PubMed:23644597). Involved in the pathway leading to the...
Schlagworte: | Anti-PIG53, Anti-NEDD4, Anti-NEDD-4, Anti-KIAA0093, Anti-E3 ubiquitin-protein ligase NEDD4, Anti-HECT-type E3 ubiquitin... |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: A303-254A
Protein function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Specifically ubiquitinates 'Lys-63' in target proteins (PubMed:23644597). Involved in the pathway leading to the...
Schlagworte: | Anti-PIG53, Anti-NEDD4, Anti-NEDD-4, Anti-KIAA0093, Anti-E3 ubiquitin-protein ligase NEDD4, Anti-HECT-type E3 ubiquitin... |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: NSJ-F52006-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Nedd4 is one of a group of mouse genes that show developmentally regulated expression in mouse embryonic brain. Nedd4 is expressed in various other embryonic tissues and persists in most adult tissues. Protein function: E3 ubiquitin-protein ligase which accepts ubiquitin...
Schlagworte: | Anti-NEDD4, Anti-PIG53, Anti-NEDD-4, Anti-KIAA0093, EC=6.3.2.-, Anti-E3 ubiquitin-protein ligase NEDD4, Anti-Cell... |
Anwendung: | WB, IHC, FC, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 326,00 €
Artikelnummer: E-AB-62147.120
This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT...
Schlagworte: | Anti-PIG53, Anti-NEDD4, Anti-NEDD-4, Anti-KIAA0093, Anti-E3 ubiquitin-protein ligase NEDD4, Anti-HECT-type E3 ubiquitin... |
Anwendung: | WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 198,00 €
Artikelnummer: Cay26139-5
Heclin is an inhibitor of HECT E3 ubiquitin ligases (IC50s = 6.8, 6.3, and 6.9 µM for Smurf2, Nedd4, and WWP1 HECT ligase domains, respectively). It inhibits autoubiquitination of Smurf2 in HEK293 cells expressing the human enzyme (IC50 = 9 µM) and reduces ubiquitination of Dishevelled 2 in HEK293 cells expressing...
Schlagworte: | N-(4-acetylphenyl)-3-(5-ethyl-2-furanyl)-2-propenamide |
Anwendung: | HECT-type E3 ubiquitin ligase inhibitor |
CAS | 890605-54-6 |
MW: | 283.3 D |
ab 43,00 €
Artikelnummer: G-CAB0552.100
Anwendung: | IHC, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 352,00 €
Artikelnummer: G-CAB4385.100
Protein function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Specifically ubiquitinates 'Lys-63' in target proteins (PubMed:23644597). Involved in the pathway leading to the...
Schlagworte: | Anti-PIG53, Anti-NEDD4, Anti-NEDD-4, Anti-KIAA0093, Anti-E3 ubiquitin-protein ligase NEDD4, Anti-HECT-type E3 ubiquitin... |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 352,00 €
Artikelnummer: ATA-HPA039883.100
Protein function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Specifically ubiquitinates 'Lys-63' in target proteins (PubMed:23644597). Involved in the pathway leading to the...
Schlagworte: | Anti-PIG53, Anti-NEDD4, Anti-NEDD-4, Anti-KIAA0093, Anti-E3 ubiquitin-protein ligase NEDD4, Anti-HECT-type E3 ubiquitin... |
Anwendung: | IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 300,00 €