Zu "K10580" wurden 35 Artikel gefunden!
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NSC697923
Artikelnummer: TGM-T6611-100mg
Description: NSC-697923 (2-[(4-methylphenyl)sulfonyl]-5-nitrofuran), a potent inhibitor of UBE2N (ubiquitin-conjugating enzyme E2 N, Ubc13), exhibits its role in inducing cell death in neuroblastoma (NB) cells through two distinct mechanisms. In p53 wild-type NB cells, NSC-697923 promotes the nuclear importation of...
| Schlagworte: | 2-[(4-methylphenyl)sulfonyl]-5-nitrofuran |
| Anwendung: | Ubc13-Uev1A inhibitor |
| CAS | 343351-67-7 |
| MW: | 267.26 D |
ab 40,00 €
NSC697923
Artikelnummer: AG-CR1-3519-M005
Synthetic. Selective Ub-conjugating enzyme (E2) complex Ubc13-Uev1A inhibitor. Inhibits the formation of the Ubc13~Ub conjugate. NF-kappaB activation inhibitor. Inhibits proliferation and survival of ABC-DLBCL and GCB-DLBCL (diffuse large B cell lymphoma) cells.
| Schlagworte: | 2-(4-Methylphenyl)sulfonyl-5-nitrofuran |
| Anwendung: | Ubc13-Uev1A inhibitor |
| CAS | 343351-67-7 |
| MW: | 267,3 D |
ab 28,00 €
UbcH13 (UBE2N), active, human recombinant, N-terminal...
Artikelnummer: BPS-80323
UbcH13, also known als UBE2N, amino acids 2-end, with N-terminal His-tag, expressed in E.coli. UbcH13 is an E2 conjugating enzyme.
| Schlagworte: | BLU, UBE2N, Ubc13, UbcH13, Ubiquitin-protein ligase N, Ubiquitin carrier protein N, Ubiquitin-conjugating enzyme E2 N, E2... |
| Anwendung: | Enzyme kinetics, inhibitor screening, profiling |
| MW: | 17.6 kD |
378,00 €
Anti-UBC13 (Ubiquitin-conjugating enzyme E2 N)
Artikelnummer: 600-101-342
Protein function: The UBE2V1-UBE2N and UBE2V2-UBE2N heterodimers catalyze the synthesis of non-canonical 'Lys-63'-linked polyubiquitin chains. This type of polyubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of...
| Schlagworte: | Anti-BLU, Anti-UBE2N, Anti-Ubc13, Anti-UbcH13, EC=6.3.2.19, Anti-Ubiquitin-protein ligase N, Anti-Ubiquitin carrier... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
719,00 €
NSC697923
Artikelnummer: BPS-27765-1
NSC697923 is a cell-permeable and selective inhibitor of the Ub-conjugating enzyme (E2) complex Ubc13-Uev1A. It is believed to act by disrupting formation of the Ubc13:Ub conjugate. Shown to inhibit proliferation and survival of certain B-cell lymphoma cells.
| Schlagworte: | 2-(4-Methylphenyl)sulfonyl-5-nitrofuran, |
| Anwendung: | Cell-permeable Ubc13-Uev1A inhibitor |
| MW: | 267.3 D |
ab 303,00 €
NSC 697923
Artikelnummer: Cay15346-1
NSC 697923 is a selective inhibitor of the E2 ubiquitin-conjugating enzyme Ubc13 when heterodimerized with Uev1A, blocking polyubiquitin chain formation at concentrations of 0.5 to 2 µM in vitro. It also inhibits NF-kappaB activation by PMA and other agonists, presumably through its effects on Ubc13. NSC 697923...
| Schlagworte: | 2-[(4-methylphenyl)sulfonyl]-5-nitro-furan |
| Anwendung: | Ubc13 inhibitor |
| CAS | 343351-67-7 |
| MW: | 267.3 D |
ab 32,00 €
UBCH13 TR-FRET Assay Kit
Artikelnummer: BPS-79741
UBCH13 is a noncanonical ubiquitin conjugating enzyme (E2) that has been implicated in a variety of cellular signaling processes due to its ability to catalyze the formation of lysine 63-linked polyubiquitin chains on various substrates. In particular, UBCH13 is required for signaling by a variety of receptors...
| Schlagworte: | UBE2N, HEL-S-71, UBC13, UBCHBEN, UBC13, UbcH-ben, ubiquitin conjugating enzyme E2 N, |
| Anwendung: | Drug discovery, HTS |
| Spezies-Reaktivität: | human |
1.628,00 €
Anti-UBE2N
Artikelnummer: E-AB-53571.120
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s....
| Schlagworte: | Anti-BLU, Anti-Ubc13, Anti-UBE2N, Anti-UbcH13, Anti-Ubiquitin-protein ligase N, Anti-Ubiquitin carrier protein N, Anti-E2... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Anti-UBE2N / UBC13
Artikelnummer: ARG43183.100
Protein function: The UBE2V1-UBE2N and UBE2V2-UBE2N heterodimers catalyze the synthesis of non-canonical 'Lys-63'-linked polyubiquitin chains. This type of polyubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of...
| Schlagworte: | Anti-BLU, Anti-UBE2N, Anti-Ubc13, Anti-Ubc13, Anti-UbcH13, Anti-UbcH13, Anti-Ubiquitin-protein ligase N,... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
658,00 €
Anti-UBE2N / UBC13
Artikelnummer: ARG43191.50
Protein function: The UBE2V1-UBE2N and UBE2V2-UBE2N heterodimers catalyze the synthesis of non-canonical 'Lys-63'-linked polyubiquitin chains. This type of polyubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of...
| Schlagworte: | Anti-BLU, Anti-UBE2N, Anti-Ubc13, Anti-Ubc13, Anti-UbcH13, Anti-UbcH13, Anti-Ubiquitin-protein ligase N,... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
625,00 €
Anti-UBE2N
Artikelnummer: ATA-HPA044976.100
Protein function: The UBE2V1-UBE2N and UBE2V2-UBE2N heterodimers catalyze the synthesis of non-canonical 'Lys-63'-linked polyubiquitin chains. This type of polyubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of...
| Schlagworte: | Anti-BLU, Anti-Ubc13, Anti-UBE2N, Anti-UbcH13, Anti-Ubiquitin-protein ligase N, Anti-Ubiquitin carrier protein N,... |
| Anwendung: | ICC, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 320,00 €
Anti-UBE2N / Ubc13
Artikelnummer: NSJ-RQ7424
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Ubiquitin-conjugating enzyme E2 N is a protein that in humans is encoded by the UBE2N gene. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at...
| Schlagworte: | Anti-BLU, Anti-Ubc13, Anti-UBE2N, Anti-UbcH13, Anti-Ubiquitin-protein ligase N, Anti-Ubiquitin carrier protein N,... |
| Anwendung: | WB, IF, FC, IHC (paraffin), Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
772,00 €