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Zu "K10247" wurden 24 Artikel gefunden!
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Artikelnummer: Cay36142-1
ELOVL1-22 is an inhibitor of ELOVL fatty acid elongase 1 (ELOVL1). It reduces lysohexacosanoylphosphatidylcholine (LPC(C26:0)) synthesis in HEK293 cells (IC50 = 400 pM), a marker of ELOVL1 inhibition, and is selective for ELOVL1 over ELOVL4, -6, and -7 (IC50s = >50 µM for all), as well as a panel of 34 receptors at...
| Schlagworte: | (S)-4-(6-((1S,3R)-3-(1H-pyrazol-1-yl)cyclobutoxy)pyrimidin-4-yl)-2-phenylmorpholine |
| Anwendung: | ELOVL1 inhibitor |
| MW: | 377.4 D |
ab 147,00 €
Artikelnummer: G-HUFI01259.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Artikelnummer: E-AB-11189.120
Elongation of very long chain fatty acid-like (ELOVL) proteins 1-6 are members of the ELO family of proteins, which play an important role in tissue-specific biosynthesis of very long chain fatty acids and sphingolipids. The ELOVL proteins act as catalysts in fatty acid elongation reduction and localize to the...
| Schlagworte: | Anti-SSC1, Anti-CGI-88, Anti-ELOVL FA elongase 1, Anti-ELOVL fatty acid elongase 1, Anti-3-keto acyl-CoA synthase ELOVL1,... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 89,00 €
Artikelnummer: ATA-HPA056557.100
Protein function: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle (PubMed:29496980, PubMed:30487246). This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty...
| Schlagworte: | Anti-SSC1, Anti-CGI-88, Anti-ELOVL FA elongase 1, Anti-ELOVL fatty acid elongase 1, Anti-3-keto acyl-CoA synthase ELOVL1,... |
| Anwendung: | ICC, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 246,00 €
Artikelnummer: ELK-ELK4667.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ELOVL1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ELOVL1....
| Schlagworte: | SSC1, CGI-88, ELOVL FA elongase 1, ELOVL fatty acid elongase 1, 3-keto acyl-CoA synthase ELOVL1, Very long chain... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 374,00 €
Artikelnummer: CSB-PA002321.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-SSC1, Anti-CGI-88, Anti-ELOVL FA elongase 1, Anti-ELOVL fatty acid elongase 1, Anti-3-keto acyl-CoA synthase ELOVL1,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 126,00 €
Artikelnummer: CSB-PA262320.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-SSC1, Anti-CGI-88, Anti-ELOVL FA elongase 1, Anti-ELOVL fatty acid elongase 1, Anti-3-keto acyl-CoA synthase ELOVL1,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
284,00 €
Artikelnummer: CSB-PA934646.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: ELOVL1. Antigen Species: Human
| Schlagworte: | Anti-SSC1, Anti-CGI-88, Anti-ELOVL FA elongase 1, Anti-ELOVL fatty acid elongase 1, Anti-3-keto acyl-CoA synthase ELOVL1,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 167,00 €
Artikelnummer: CSB-PA939360.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: ELOVL1. Antigen Species: Human
| Schlagworte: | Anti-SSC1, Anti-CGI-88, Anti-ELOVL FA elongase 1, Anti-ELOVL fatty acid elongase 1, Anti-3-keto acyl-CoA synthase ELOVL1,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 167,00 €
Artikelnummer: TGM-T9578-100mg
Description: ELOVL1-IN-1 (1-(2-Fluorophenyl)-N-(1-(2-fluoropyridin-4-YL)-1H-pyrazol-3-YL)cyclopropane-1-carboxamide) is an ELOVL1 inhibitor. ELOVL1-IN-1 can reduce the levels of very long chain fatty acids. ELOVL1-IN-1 can be used in the study of adrenoleukodystrophy (ALD). Target: Others. Smiles:...
| Schlagworte: | 1-(2-Fluorophenyl)-N-(1-(2-fluoropyridin-4-YL)-1H-pyrazol-3-YL)cyclopropane-1-carboxamide |
| Anwendung: | ELOVL1 inhibitor |
| CAS | 2227482-41-7 |
| MW: | 340.33 D |
ab 128,00 €
Artikelnummer: G-AEKE08562.96
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ELOVL1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ELOVL1....
| Schlagworte: | ELOVL1, ELOVL fatty acid elongase 1, 3-keto acyl-CoA synthase ELOVL1, Very long chain fatty acid elongase 1, Very long... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
694,00 €
Artikelnummer: Cay35323-1
ELOVL1-27 is an inhibitor of ELOVL fatty acid elongase 1 (ELOVL1, IC50 = 900 nM). It reduces lysohexacosanoylphosphatidylcholine (LPC(C26:0)) synthesis in HEK293 cells (IC50 = 13 nM), as well as in primary fibroblasts isolated from patients with cerebral adrenoleukodystrophy (CALD) or adrenomyeloneuropathy (AMN,...
| Schlagworte: | 1-(2-fluorophenyl)-N-[1-(2-fluoro-4-pyridinyl)-1H-pyrazol-3-yl]-cyclopropanecarboxamide |
| Anwendung: | ELOVL1 inhibitor |
| CAS | 2227482-41-7 |
| MW: | 340.3 D |
ab 147,00 €